Intranasal Administration of Autoantigenic Peptide /Poly (I:C) Enhanced protective efficacy to Diabetes induced by Alum-adjuvant Treatment in NOD Mice
Project/Area Number |
21790874
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Metabolomics
|
Research Institution | Nagasaki University |
Principal Investigator |
NAKAMURA Kan Nagasaki University, 病院, 医員 (70530426)
|
Project Period (FY) |
2009 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | 1型糖尿病 / 粘膜免疫 / 抗原特異的免疫寛容療法 |
Research Abstract |
Combination of single subQ-B:9-23/Alum and intranasal-B:9-23/Poly(I:C) less developed diabetes compared to the mice with single subQ-B:9-23/Alum alone or control mice up to 48 age-weeks (P<0.05).
|
Report
(3 results)
Research Products
(13 results)