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Basic Study on Stereotactic Body Radiation Therapy for Centrally Located Lung Cancer

Research Project

Project/Area Number 21791188
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Radiation science
Research InstitutionKyoto University

Principal Investigator

MATSUO Yukinori  Kyoto University, 医学研究科, 助教 (80456897)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywords体幹部定位放射線治療 / 肺癌 / 癌 / 放射線 / 定位放射線治療
Research Abstract

Stereotactic body radiation therapy (SBRT) is an important treatment option for inoperable patients with early-stage lung cancer. Application of SBRT for centrally located lung cancer was limited. I conducted basic studies on SBRT for central tumors. Following issues were evaluated : dose-response relationship in local control, tumor motion during the treatment, differences between dose-calculation algorithms, and accuracies of body fixation in SBRT for the lung. After that, I played a role in making a multi-institutional trial of SBRT for central tumor.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (42 results)

All 2011 2010 2009 Other

All Journal Article (24 results) (of which Peer Reviewed: 21 results) Presentation (15 results) Book (3 results)

  • [Journal Article] Prognostic factors in stereotactic body radiotherapy for non-small-cell lung cancer.2011

    • Author(s)
      Matsuo Y, Shibuya K, Nagata Y, Takayama K, Norihisa Y, Mizowaki T, Narabayashi M, Sakanaka K, Hiraoka M.
    • Journal Title

      Int J Radiat Oncol Biol Phys. 79

      Pages: 1104-1111

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Prognostic factors in stereotactic body radiotherapy for non-small-cell lung cancer.2011

    • Author(s)
      Matsuo Y, Shibuya K, Nagata Y, Takayama K, Norihisa Y, Mizowaki T, Narabayashi M, Sakanaka K, Hiraoka M.
    • Journal Title

      Int J Radiat Oncol Biol Phys.

      Volume: 79 Pages: 1104-11

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Positional reproducibility of pancreatic tumors under end-exhalation breath-hold conditions using a visual feedback technique.2011

    • Author(s)
      Nakamura M, Shibuya K, Shiinoki T, Matsuo Y, Nakamura A, Nakata M, Sawada A, Mizowaki T, Hiraoka M.
    • Journal Title

      Int J Radiat Oncol Biol Phys.

      Volume: (In press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of FDG-PET images after stereotactic body radiation therapy for lung cancer.2010

    • Author(s)
      Matsuo Y, Nakamoto Y, Nagata Y, Shibuya K, Takayama K, Norihisa Y, Narabayashi M, Mizowaki T, Saga T, Higashi T, Togashi K, Hiraoka M.
    • Journal Title

      Radiother Oncol. 97

      Pages: 200-204

    • NAID

      120002674607

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Salvage lung resection for non-small cell lung cancer after stereotactic body radiotherapy in initially operable patients.2010

    • Author(s)
      Chen F, Matsuo Y, Yoshizawa A, Sato T, Sakai H, Bando T, Okubo K, Shibuya K, Date H.
    • Journal Title

      J Thorac Oncol. 5

      Pages: 1999-2002

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Stereotactic body radiation therapy for lung cancer: achievements and perspectives.2010

    • Author(s)
      Hiraoka M, Matsuo Y, Takayama K.
    • Journal Title

      Jpn J Clin Oncol. 40

      Pages: 846-854

    • Related Report
      2010 Final Research Report
  • [Journal Article] Impact of multileaf collimator width on intraprostatic dose painting plans for dominant intraprostatic lesion of prostate cancer.2010

    • Author(s)
      Abe E, Mizowaki T, Norihisa Y, Narita Y, Matsuo Y, Narabayashi M, Nagata Y, Hiraoka M.
    • Journal Title

      J Appl Clin Med Phys. 11

      Pages: 3193-3193

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of FDG-PET images after stereotactic body radiation therapy for lung cancer.2010

    • Author(s)
      Matsuo Y, Nakamoto Y, Nagata Y, Shibuya K, Takayama K, Norihisa Y, Narabayashi M, Mizowaki T, Saga T, Higashi T, Togashi K, Hiraoka M.
    • Journal Title

      Radiother Oncol.

      Volume: 97 Pages: 200-4

    • NAID

      120002674607

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Salvage lung resection for non-small cell lung cancer after stereotactic body radiotherapy in initially operable patients.2010

    • Author(s)
      Chen F, Matsuo Y, Yoshizawa A, Sato T, Sakai H, Bando T, Okubo K, Shibuya K, Date H.
    • Journal Title

      J Thorac Oncol.

      Volume: 5 Pages: 1999-2002

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Stereotactic body radiation therapy for lung cancer : achievements and perspectives.2010

    • Author(s)
      Hiraoka M, Matsuo Y, Takayama K.
    • Journal Title

      Jpn J Clin Oncol.

      Volume: 40 Pages: 846-54

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of multileaf collimator width on intraprostatic dose painting plans for dominant intraprostatic lesion of prostate cancer.2010

    • Author(s)
      Abe E, Mizowaki T, Norihisa Y, Narita Y, Matsuo Y, Narabayashi M, Nagata Y, Hiraoka M.
    • Journal Title

      J Appl Clin Med Phys.

      Volume: 11 Pages: 3193-3193

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 京都大学におけるIMRT2009

    • Author(s)
      松尾幸憲, 他
    • Journal Title

      臨床放射線 54

      Pages: 590-595

    • Related Report
      2010 Final Research Report
  • [Journal Article] Measurement of Interfraction Variations in Position and Size of Target Volumes in Stereotactic Body Radiotherapy for Lung Cancer.2009

    • Author(s)
      Matsugi K, Narita Y, Sawada A, Nakamura M, Miyabe Y, Matsuo Y, Narabayashi M, Norihisa Y, Mizowaki T, Hiraoka M.
    • Journal Title

      Int J Radiat Oncol Biol Phys 75

      Pages: 543-548

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Survey of Stereotactic Body Radiation Therapy in Japan by the Japan 3-D Conformal External Beam Radiotherapy Group.2009

    • Author(s)
      Nagata Y, Hiraoka M, Mizowaki T, Narita Y, Matsuo Y, Norihisa Y, Onishi H, Shirato H.
    • Journal Title

      Int J Radiat Oncol Biol Phys. 75

      Pages: 343-347

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of Audio Coaching on Correlation of Abdominal Displacement With Lung Tumor Motion.2009

    • Author(s)
      Nakamura M, Narita Y, Matsuo Y, Narabayashi M, Nakata M, Sawada A, Mizowaki T, Nagata Y, Hiraoka M.
    • Journal Title

      Int J Radiat Oncol Biol Phys 75

      Pages: 558-563

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] New algorithm to simulate organ movement and deformation for four-dimensional dose calculation based on a three-dimensional CT and fluoroscopy of the thorax.2009

    • Author(s)
      Miyabe Y, Narita Y, Mizowaki T, Matsuo Y, Takayama K, Takahashi K, Kaneko S, Kawada N, Maruhashi A, Hiraoka M.
    • Journal Title

      Med Phys 36

      Pages: 4328-4339

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Impact of motion velocity on four-dimensional target volumes: a phantom study.2009

    • Author(s)
      Nakamura M, Narita Y, Sawada A, Matsugi K, Nakata M, Matsuo Y, Mizowaki T, Hiraoka M.
    • Journal Title

      Med Phys. 36

      Pages: 1610-1617

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 京都大学におけるIMRT2009

    • Author(s)
      松尾幸憲, 他
    • Journal Title

      臨床放射線 54巻

      Pages: 590-595

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Measurement of Interfraction Variations in Position and Size of Target Volumes in Stereotactic Body Radiotherapy for Lung Cancer2009

    • Author(s)
      Matsugi K, Narita Y, Sawada A, Nakamura M, Miyabe Y, Matsuo Y, Narabayashi M, Norihisa Y, Mizowaki T, Hiraoka M
    • Journal Title

      Int J Radiat Oncol Biol Phys 75

      Pages: 543-548

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Survey of Stereotactic Body Radiation Therapy in Japan by the Japan 3-D Conformal External Beam Radiotherapy Group2009

    • Author(s)
      Nagata Y, Hiraoka M, Mizowaki T, Narita Y, Matsuo Y, Norihisa Y, Onishi H, Shirato H
    • Journal Title

      Int J Radiat Oncol Biol Phys 75

      Pages: 343-347

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of Audio Coaching on Correlation of Abdominal Displacement With Lung Tumor Motion2009

    • Author(s)
      Nakamura M, Narita Y, Matsuo Y, Narabayashi M, Nakata M, Sawada A, Mizowaki T, Nagata Y, Hiraoka M
    • Journal Title

      Int J Radiat Oncol Biol Phys 75

      Pages: 558-563

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] New algorithm to simulate organ movement and deformation for four-dimensional dose calculation based on a three-dimensional CT and fluoroscopy of the thorax2009

    • Author(s)
      Miyabe Y, Narita Y, Mizowaki T, Matsuo Y, Takayama K, Takahashi K, Kaneko S, Kawada N, Maruhashi A, Hiraoka M
    • Journal Title

      Med Phys 36

      Pages: 4328-4339

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of motion velocity on four-dimensional target volumes : a phantom study.2009

    • Author(s)
      Nakamura M, Narita Y, Sawada A, Matsugi K, Nakata M, Matsuo Y, Mizowaki T, Hiraoka M
    • Journal Title

      Med Phys 36

      Pages: 1610-1617

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Positional reproducibility of pancreatic tumors under end-exhalation breath-hold conditions using a visual feedback technique.

    • Author(s)
      Nakamura M, Shibuya K, Shiinoki T, Matsuo Y, Nakamura A, Nakata M, Sawada A, Mizowaki T, Hiraoka M.
    • Journal Title

      Int J Radiat Oncol Biol Phys. (in press)

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Presentation] MHI-TM2000(Vero)を用いた動体追尾照射の実施に向けた取り組み2011

    • Author(s)
      松尾幸憲
    • Organizer
      第23回日本高精度放射線外部照射研究会
    • Place of Presentation
      秋葉原コンベンションホール(東京)
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 肺定位放射線治療における線量計算アルゴリズムの肺線量指標への影響および放射線肺臓炎との関連に関する検討2010

    • Author(s)
      松尾幸憲
    • Organizer
      第21回日本高精度放射線外部照射研究会
    • Place of Presentation
      くまもと県民交流館パレア
    • Year and Date
      2010-01-30
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] Evaluation of Dose-Volume Metrics Associated with Local Recurrence after Stereotactic Body Radiation Therapy for Lung Cancer.2010

    • Author(s)
      Matsuo Y
    • Organizer
      Chicago Multidisciplinary Symposium in Thoracic Oncology
    • Place of Presentation
      Hilton Chicago(米国シカゴ)
    • Related Report
      2010 Final Research Report
  • [Presentation] 肺癌定位放射線治療後の局所制御に関連する線量体積因子の検討2010

    • Author(s)
      松尾幸憲
    • Organizer
      日本放射線腫瘍学会第23回学術大会
    • Place of Presentation
      東京ベイ舞浜ホテルクラブリゾート(浦安)
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 京都大学における肺定位放射線治療の高度化~放射線腫瘍医の立場から~2010

    • Author(s)
      松尾幸憲
    • Organizer
      日本放射線腫瘍学会第23回学術大会
    • Place of Presentation
      東京ベイ舞浜ホテルクラブリゾート(浦安)
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] Analysis of Dose-volume Metrics Associated with Radiation Pneumonitis after Stereotactic Body Radiotherapy for Lung Cancer.2010

    • Author(s)
      Matsuo Y
    • Organizer
      52nd Annual Meeting of the American Society for Radiation Oncology
    • Place of Presentation
      San Diego Convention Center (米国サンディエゴ)
    • Related Report
      2010 Final Research Report
  • [Presentation] Stereotactic Body Radiotherapy for Non-Small Cell Lung Cancer: Kyoto University Experience.2010

    • Author(s)
      Matsuo Y
    • Organizer
      9th International Conference of the Asian Clinical Oncology Society
    • Place of Presentation
      岐阜グランドホテル(岐阜)
    • Related Report
      2010 Final Research Report
  • [Presentation] Stereotactic Body Radiotherapy for Non-Small Cell Lung Cancer : Kyoto University Experience2010

    • Author(s)
      Matsuo Y
    • Organizer
      the 9th International Conference of the Asian Clinical Oncology Society
    • Place of Presentation
      岐阜グランドホテル(岐阜)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Analysis of Dose-volume Metrics Associated with Radiation Pneumonitis after Stereotactic Body Radiotherapy for Lung Cancer2010

    • Author(s)
      Matsuo Y.
    • Organizer
      52^<nd> Annual Meeting of the American Society for Radiation Oncology
    • Place of Presentation
      San Diego Convention Center(米国サンディエゴ)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Evaluation of Dose-Volume Metrics Associated with Local Recurrence after Stereotactic Body Radiation Therapy for Lung Cancer2010

    • Author(s)
      Matsuo Y.
    • Organizer
      Chicago Multidisciplinary Symposium in Thoracic Oncology
    • Place of Presentation
      Hilton Chicago(米国シカゴ)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 肺定位放射線治療の適応と課題:T2腫瘍について2009

    • Author(s)
      松尾幸憲
    • Organizer
      日本放射線腫瘍学会第22回学術大会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2009-09-17
    • Related Report
      2010 Final Research Report
  • [Presentation] 肺定位放射線治療の適応と課題:T2腫瘍について2009

    • Author(s)
      松尾幸憲
    • Organizer
      日本放射線腫瘍学会 第22回学術大会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2009-09-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] 原発性肺癌に対する定位放射線治療における予後因子の検討2009

    • Author(s)
      松尾幸憲
    • Organizer
      第68回日本医学放射線学会総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-04-17
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] Local Recurrence in Long-term Survivors after Stereotactic Body Radiation Therapy for Lung Cancer.2009

    • Author(s)
      Matsuo Y
    • Organizer
      ASTRO's 51st Annual Meeting
    • Place of Presentation
      シカゴ、米国
    • Related Report
      2010 Final Research Report
  • [Presentation] Local Recurrence in Long-term Survivors after Stereotactic Body Radiation Therapy for Lung Cancer2009

    • Author(s)
      Yukinori Matsuo
    • Organizer
      ASTRO's 51st Annual Meeting
    • Place of Presentation
      シカゴ、米国
    • Related Report
      2009 Annual Research Report
  • [Book] State of the Art2011

    • Author(s)
      Matsuo Y, Shibuya K, Narabayashi M,Hiraoka M.Springer
    • Publisher
      Shaped Beam Radiosurgery
    • Related Report
      2010 Final Research Report
  • [Book] Shaped Beam Radiosurgery : State of the Art2011

    • Author(s)
      Matsuo Y, Shibuya K, Narabayashi M, Hiraoka M.
    • Publisher
      Springer
    • Related Report
      2010 Annual Research Report
  • [Book] がん・放射線療法20102010

    • Author(s)
      松尾幸憲
    • Publisher
      篠原出版新社
    • Related Report
      2010 Annual Research Report 2010 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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