| Project/Area Number |
21791198
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Radiation science
|
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| Research Institution | The University of Tokushima |
|---|
Principal Investigator |
UTO Yoshihiro The University of Tokushima, 大学院・ソシオテクノサイエンス研究部, 准教授 (20304553)
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| Project Period (FY) |
2009 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | 発育鶏卵 / 放射線増感剤 / 固形腫瘍 / 低酸素細胞放射線増感剤 / グルコース / 腫瘍移植鶏卵 / 薬物動態 |
|---|
| Research Abstract |
Chick embryo have been used as alternative experimental animals in various research fields, including virology, immunology, toxicology, oncology, and embryology. In this research, we developed the screening system of in vivo radiosensitizing activity of etanidazole as a radiosensitizer using tumor-bearing chick embryo. Moreover, we succeeded the evaluation of pharmacokinetic property of etanidazole using this model.
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