Near-infrared topography to detect liver congestion area and tumor location

• Project/Area Number: 21791271
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Digestive surgery
• Research Institution: The University of Tokyo
• Principal Investigator: KANEKO Junichi The University of Tokyo, 医学部附属病院, 特任講師 (50328118)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2009: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
• Keywords: 肝臓外科学 / 蛍光薬剤 / 近赤外光 / トポグラフィ / 近赤外光トポグラフィ / 肝腫瘍 / インドシアニングリーン

Research Abstract

We confirmed an indocyanine green fluorescent of liver tumor after an indocyanine green injection. The fuorescent medical agent facilitated a performance of near-infrared topography to detect liver congestion area and tumor location. Furthermore, we made a fluorescent mouse model using diethylnitrosamine-induced liver tumor. We found correlation between near-infrared light and a fluorescent liver tumor.

Research Products

• [Journal Article] Application of fluorescent cholangiography to single-incision laparoscopic cholecystectomy. (2011)
  • Author(s): Ishizawa T, Kaneko J, Inoue Y, Takemura N, Seyama Y, Aoki T, Beck Y, Sugawara Y, Hasegawa K, Harada N, Ijichi M, Kusaka K, Shibasaki M, Bandai Y, Kokudo N.
  • Journal Title: Surg Endosc (Epub ahead of print)
  • Peer Reviewed
• [Journal Article] Discrepancy between estimated and actual weight of partial liver graft from living donors. (2011)
  • Author(s): Satou S, Sugawara Y, Tamura S, Yamashiki N, Kaneko J, Aoki T, Hasegawa K, Beck Y, Makuuchi M, Kokudo N.
  • Journal Title: J Hepatobiliary Pancreat Sci. (Epub ahead of print)
  • NAID: 10029287771
  • Peer Reviewed
• [Journal Article] Single artery reconstruction in left liver transplantation. (2011)
  • Author(s): Sugawara Y, Tamura S, Kaneko J, Iida T, Mihara M, Makuuchi M, Koshima I, Kokudo N.
  • Journal Title: Surgery. 149(6) Pages: 841-845
  • Peer Reviewed
• [Journal Article] Living Donor Liver Transplantations in HIV-and Hepatitis C Virus-Coinfected Hemophiliacs : Experience in a Single Center. (2011)
  • Author(s): Tsukada K, Sugawara Y, Kaneko J, Tamura S, Tachikawa N, Morisawa Y, Okugawa S, Kikuchi Y, Oka S, Kimura S, Yatomi Y, Makuuchi M, Kokudo N, Koike K.
  • Journal Title: Transplantation. 91(11) Pages: 1261-1264
  • Peer Reviewed
• [Journal Article] Hepatobiliary Surgery Guided by a Novel Fluorescent Imaging Technique for Visualizing Hepatic Arteries, Bile Ducts, and Liver Cancers on Color Images. (2011)
  • Author(s): Kawaguchi Y, Ishizawa T, Masuda K, Sato S, Kaneko J, Aoki T, Beck Y, Sugawara Y, Hasegawa K, Kokudo N.
  • Journal Title: J Am Coll Surg Volume: (in press(掲載確定))
  • Peer Reviewed
• [Journal Article] Application of fluorescent cholangiography to single-incision laparoscopic cholecystectomy. (2011)
  • Author(s): Ishizawa T, Kaneko J, Inoue Y, Takemura N, Seyama Y, Aoki T, Beck Y, Sugawara Y, Hasegawa K, Harada N, Ijichi M, Kusaka K, Shibasaki M, Bandai Y, Kokudo N.
  • Journal Title: Surg Endosc Volume: (in press(掲載確定))
  • Peer Reviewed
• [Journal Article] Discrepancy between estimated and actual weight of partial liver graft from living donors. (2011)
  • Author(s): Satou S, Sugawara Y, Tamura S, Yamashiki N, Kaneko J, Aoki T, Hasegawa K, Beck Y, Makuuchi M, Kokudo N.
  • Journal Title: J Hepatobiliary Pancreat Sci. Volume: (in press(掲載確定))
  • NAID: 10029287771
  • Peer Reviewed
• [Journal Article] Sarcomatous change of hepatocellular carcinoma in a patient undergoing living donor liver transplantation. (2010)
  • Author(s): Kaneko J, Sugawara Y, Togashi J, Tamura S, Motoi R, Fukayama M, Kokudo N.
  • Journal Title: Biosci Trends. 4(5) Pages: 279-282
  • Peer Reviewed
• [Journal Article] Fluorescent cholangiography illuminating the biliary tree during laparoscopic cholecystectomy. (2010)
  • Author(s): Ishizawa T, Bandai Y, Ijichi M, Kaneko J, Hasegawa K, Kokudo N.
  • Journal Title: Br J Surg. 97(9) Pages: 1369-1377
  • Peer Reviewed
• [Journal Article] Indocyanine green(ICG)蛍光観察による肝切除 (2010)
  • Author(s): 金子順一、石沢武彰、國土典宏
  • Journal Title: 臨床外科 65 Pages: 642-649
• [Journal Article] Discrepancy between estimated and actual weight of partial liver graft from living donors. (2010)
  • Author(s): Kaneko J, Sugawara Y, Togashi J, Tamura S, Motoi R, Fukayama M, Kokudo N.
  • Journal Title: Biosci Trends Volume: 4 Pages: 279-282
  • NAID: 10029287771
  • Peer Reviewed
• [Journal Article] Indocyanine green (ICG)蛍光観察による肝切除 (2010)
  • Author(s): 金子順一
  • Journal Title: 臨床外科 Volume: 65 Pages: 642-649
• [Journal Article] Hepatobiliary Surgery Guided by a Novel Fluorescent Imaging Technique for Visualizing Hepatic Arteries, Bile Ducts, and Liver Cancers on Color Images.
  • Author(s): Kawaguchi Y, Ishizawa T, Masuda K, Sato S, Kaneko J, Aoki T, Beck Y, Sugawara Y, Hasegawa K, Kokudo N.
  • Journal Title: J Am Coll Surg. 212(6)
  • Peer Reviewed
• [Presentation] (2011)
  • Author(s): 金子順一、石沢武彰、増田晃一、宮田陽一、河口義邦、山下俊、佐藤彰一、有田淳一、青木琢、別宮好文、菅原寧彦、長谷川潔、國土典宏
  • Organizer: 第111回日本外科学会定期学術集会(震災のため紙上開催)
  • Place of Presentation: (日本外科学会雑誌への抄録掲載)
  • Year and Date: 2011-05-26
• [Presentation] ICG蛍光法による手術ナビゲーションを応用した肝切除 (2011)
  • Author(s): 金子順一
  • Organizer: 第111回日本外科学会定期学術集会
  • Place of Presentation: (日本外科学会雑誌への抄録掲載(震災のため紙上開催))
  • Year and Date: 2011-05-26
• [Presentation] 腹腔鏡下肝切除におけるインドシアニングリーン蛍光硬性鏡の有用性 (2009)
  • Author(s): 金子順一、石沢武彰、清水篤志、脊山泰治、長谷川潔、別宮好文、新田浩幸、若林剛、國土典宏
  • Organizer: 第3回肝臓内視鏡外科研究会
  • Place of Presentation: 新宿
  • Year and Date: 2009-12-03
• [Remarks] ホームページ等
  • URL: http://www.h.u-tokyo.ac.jp/transplant/
• [Remarks]
  • URL: http://www.h.u-tokyo.ac.jp/transplant/
• [Remarks]
  • URL: http://www.h.u-tokyo.ac.jp/transplant/