Pathophysiology of preeclampsia-the role of autophagy treated with cytokines
Project/Area Number |
21791546
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Obstetrics and gynecology
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Research Institution | University of Toyama |
Principal Investigator |
NAKASHIMA Akitoshi University of Toyama, 大学院・医学薬学研究部, 助教 (00436792)
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Project Period (FY) |
2009 – 2010
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Project Status |
Completed (Fiscal Year 2010)
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Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | 生殖医学 / オートファジー / 妊娠 / 妊娠高血圧症候群 / サイトカイン / 可溶型エンドグリン / 妊娠免疫 / 妊娠高血圧候群 / 低酸素 |
Research Abstract |
A decrease of extravillous trophoblast invasion was correlated with the inhibition of autophagy by soluble endoglin, which increases in serum in preeclamsia patients. This result could suggest the correlation between autophagy and pathophysiology of preeclampsia.
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Report
(3 results)
Research Products
(24 results)
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[Journal Article] A role for IL-17 in induction of an inflammation at the fetomaternal interface in preterm labour2010
Author(s)
Ito M, Nakashima A, Hidaka T, Bac ND, Ina S, Yoneda S, Shiozaki A, Sumi S, Tsuneyama K, Nikaido T, Saito S.J
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Journal Title
Reprod Immunol. 84
Pages: 75-85
Related Report
Peer Reviewed
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