The elastic properties of maxillofacial and oral region assessed by scanning acoustic microscopy

• Project/Area Number: 21791875
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Prosthetic dentistry
• Research Institution: Tohoku University
• Principal Investigator: HATORI Kouki Tohoku University, 大学院・歯学研究科, 助教 (40372320)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: 超音波顕微鏡 / 組織弾性 / 定量評価 / 下顎頭軟骨 / 歯根膜 / コラーゲン性タンパク / アグリカン / 架橋構造 / 音速変化 / 免疫組織学的観察 / I型コラーゲン / III型コラーゲン / 弾性変化 / II型コラーゲン / X型コラーゲン / 咬合力

Research Abstract

Scanning acoustic microscopy (SAM) enables us to assess the tissue elasticity based on the propagation of sound speed. The aim of this study is to elucidate the change of the elasticity of mandibular condylar cartilage (MCC) and periodontal ligaments (PDL) by using SAM. SAM clearly visualized two-dimensional distribution of the sound speed changes of MCC and PDL. The sound speed of MCC and PDL increased significantly in the course of development. Collagens and Aggrecan were expressed in the MCC and PDL. SAM is a powerful tool for evaluating the elasticity and its distribution in tissues. These results suggested that the change of tissues was induced by morphological development such as the production and/or cross-link of collagens, and the functional development such as occlusal construction.

Research Products

• [Journal Article] Distribution of Type A and B Synoviocytes in the Adhesive and Shortened Synovial Membrane during Immobilization of the Knee Joint in Rats (2010)
  • Author(s): Akira Ando, Yoshihiro Hagiwara, Yoshito Onoda, Kouki Hatori, Hideaki Suda, Eiji Itoi
  • Journal Title: Tohoku Journal of Experimental Medicine 221(12) Pages: 161-168
  • NAID: 10027084874
  • Peer Reviewed
• [Presentation] Evaluation of Cartilage-Bone Complex Assessed by High Frequency Ultrasound Imaging System (2010)
  • Author(s): Yoshihiro Hagiwara, Akira Ando, Yoshifumi Saijo, Yoshito Onoda, Hideaki Suda, Kouki Hatori, Eiichi Chimoto, Eiji Itoi
  • Organizer: The 56th Annual Meeting of the Orthopaedic Research Society.
  • Place of Presentation: Ernest N.Morial Convention Center. New Orleans, Lousiana, USA.
• [Presentation] Adhesions and Shortening of Synovial Membrane in Immobilized Rat Knee Joints (2010)
  • Author(s): Akira Ando, Yoshihiro Hagiwara, Yoshito Onoda, Kouki Hatori, Hideaki Suda, Eiichi Chimoto, Eiji Itoi
  • Organizer: The 56th Annual Meeting of the Orthopaedic Research Society.
  • Place of Presentation: Ernest N.Morial Convention Center. New Orleans, Lousiana, USA.
• [Presentation] Expression Patterns of Collagen Types I and III in the Capsule of a Rat Knee Contracture Model (2010)
  • Author(s): Yoshito Onoda, Yoshihiro Hagiwara, Akira Ando, Hiroyuki Matsui, Kouki Hatori, Hideaki Suda, Eiichi Chimoto, Eiji Itoi
  • Organizer: The 56th Annual Meeting of the Orthopaedic Research Society.
  • Place of Presentation: Ernest N.Morial Convention Center. New Orleans, Lousiana, USA.
• [Presentation] 超音波顕微鏡を利用したラット下顎頭軟骨弾性の経時的変化 (2009)
  • Author(s): 羽鳥弘毅, 萩原嘉廣, 西條芳文, 安藤晃, 伊奈慶典, 安藤浩二, 白石成, 佐藤奨, 佐々木啓一
  • Organizer: 平成21年度社団法人日本補綴歯科学会東北・北海道支部総会ならびに学術大会 平成21年度社団法人日本補綴歯科学会東北・北海道支部総会ならびに学術大会プログラム・講演内容抄録集21
  • Place of Presentation: 岩手県歯科医師会館8020プラザ,岩手県盛岡市
• [Presentation] 超音波顕微鏡を利用したラット下顎頭軟骨の経時的変化 (2009)
  • Author(s): 羽鳥弘毅, 萩原嘉廣, 西條芳文, 安藤晃, 伊奈慶典, 安藤浩二, 白石成, 佐藤奨, 佐々木啓一
  • Organizer: 社団法人日本補綴歯科学会東北・北海道支部総会ならびに学術大会
  • Place of Presentation: 岩手県歯科医師会館8020プラザ(岩手県)
• [Remarks] ホームページ等