Development of the crude drug combination denture adhesive with improvement saliva secretion effect

• Project/Area Number: 21791899
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Prosthetic dentistry
• Research Institution: Tohoku University
• Principal Investigator: HONG Guang 東北大学, 大学院・歯学研究科, 助教 (70363083)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 義歯安定剤 / 口腔乾燥症 / 生薬成分 / AQP5

Research Abstract

This research aimed at development of the crude drug combination denture adhesive with improvement saliva secretion effect. The significant differences were found among different materials in initial viscocity and adhesive strength of denture adhesive. The values of adhesive strength increased after immersing significantly in each material. Sericin can improved the surface wattability of materials. And the crude drug influenced distribution of AQP5 in salivary duct membrane of parotid positively. The results was suggest that the development of the crude drug combination denture adhesive with improvement saliva secretion effect is possible.

Research Products

• [Journal Article] The dynamic viscoelasticity and plasticizer leachability of tissue conditioners (2012)
  • Author(s): G. Hong, T. Maeda, H. Murata, K. Sasaki
  • Journal Title: Gerodontology Volume: (in press)
  • Peer Reviewed
• [Journal Article] Durability of peel bond of resilient denture liners to acrylic denture base resin (2012)
  • Author(s): T. Maeda, G. Hong, S. Sadamori, T. Hamada, Y. Akagawa
  • Journal Title: J Prosthodont Res Volume: 56 Pages: 136-141
  • NAID: 130004546632
  • Peer Reviewed
• [Journal Article] The dynamic viscoelasticity and water absorption characteristics of soft acrylic resin materials containing adipates and maleate plasticizer (2012)
  • Author(s): G. Hong, H. Tsuka, T. Maeda, Y. Akagawa, K. Sasaki
  • Journal Title: Dent Mater J Volume: 31 Pages: 139-149
  • NAID: 10030128563
  • Peer Reviewed
• [Journal Article] The influence of surface treatment of acrylic denture base resin on peel bond strength between resilient denture liners (2012)
  • Author(s): WQ Wang, G. Hong, M. Dilinuer, T. Hamada, K. Sasaki
  • Journal Title: Interface Oral Health Science 2011 Volume: 1 Pages: 285-287
  • Peer Reviewed
• [Journal Article] The surface wettability of trial acrylic denture base resins (2012)
  • Author(s): M. Dilinuer, G. Hong, WQ Wang, T. Hamada, K. Sasaki
  • Journal Title: Interface Oral Health Science 2011 Volume: 1 Pages: 252-254
  • Peer Reviewed
• [Journal Article] The dynamic viscoelasticity and plasticizer leachability of tissue conditioners (2012)
  • Author(s): G.Hong, T.Maeda, H.Murata, K.Sasaki
  • Journal Title: Gerodontology Volume: (未定)(In press)
  • Peer Reviewed
• [Journal Article] Durability of peel bond of resilient denture liners to acrylic denture base resin (2012)
  • Author(s): T.Maeda, G.Hong, S.Sadamori, T.Hamada, Y.Akagawa
  • Journal Title: J Prosthodont Res Volume: (未定)(In press)
  • NAID: 130004546632
  • Peer Reviewed
• [Journal Article] ディスプレイスメントレオメーターによる長期用軟質義歯裏装材の硬化挙動の評価 (2011)
  • Author(s): 洪光, 濱田泰三
  • Journal Title: 東北大歯誌 Volume: 29 Pages: 55-59
  • Peer Reviewed
• [Journal Article] The initial viscosity and adhesive strength of cream-type denture adhesives and oral moisturs (2011)
  • Author(s): G.Hong, H.Tsuka, MS.Dilinuer, WQ.Wang, K.Sasaki
  • Journal Title: Asian Pac J Dent Volume: 11 Pages: 45-50
  • Peer Reviewed
• [Journal Article] A questionnaire survey of dental students in Japan, China and Indonesia about denture cleansers (2010)
  • Author(s): G. Hong, YA. Li, YM. Lian, S. Sadamori, T. Hamada, H. Murata
  • Journal Title: Int Chin J Dent Volume: 10 Pages: 51-56
  • Peer Reviewed
• [Journal Article] The effect of denture adhesive on bite force until denture dislodgement using a Gnathometer (2010)
  • Author(s): G. Hong, T. Maeda, T. Hamada
  • Journal Title: Int Chin J Dent Volume: 10 Pages: 41-45
  • Peer Reviewed
• [Journal Article] Comparison of their recognition about the denture cleansers among Japanese, Chinese and Indonesian dentists (2010)
  • Author(s): G. Hong, YA. Li, YM. Lian, S. Sadamori, T. Hamada, H. Murata
  • Journal Title: Int Chin J Dent Volume: 10 Pages: 29-34
  • Peer Reviewed
• [Journal Article] Effect of PMMA polymer on the dynamic viscoelasticity and plasticizer leachability of PEMA-based tissue conditioners (2010)
  • Author(s): G. Hong, T. Maeda, Y. A. Li, S. Sadamori, T. Hamada
  • Journal Title: Dent Mater J Volume: 29 Pages: 374-380
  • NAID: 10026564712
  • Peer Reviewed
• [Journal Article] The influence of Sericin solution on wettability and antifungal effect of resin surface (2010)
  • Author(s): G. Hong, T. Hamada, T. Maeda, S. Yuda, H. Yamada
  • Journal Title: Interface Oral Health Science 2009 Volume: 1 Pages: 291-292
  • Peer Reviewed
• [Journal Article] Effect of PMMA polymer on the dynamic viscoelasticity and plasticizer leachability of PEMA-based tissue conditioners (2010)
  • Author(s): G.Hong, T.Maeda, Y.A.Li, S.Sadamori, T.Hamada
  • Journal Title: Dent Mater J (未定, Accept)
  • NAID: 10026564712
  • Peer Reviewed
• [Journal Article] The influence of Sericin solution on wettability and antifungal effect of resin surface (2010)
  • Author(s): G Hong, T.Hamada, T.Maeda, S.Yuda, H.Yamada
  • Journal Title: Interface Oral Health Science 2009 1(In press)
  • Peer Reviewed
• [Presentation] 架橋剤の添加が義歯床用アクリルレジンの表面ぬれおよび曲げ強さに及ぼす影響 (2012)
  • Author(s): ディリヌル・マイマイティサウット, 洪光, 王維奇, 佐々木啓一
  • Organizer: 第4回日本義歯ケア学会学術大会
  • Place of Presentation: 長崎
  • Year and Date: 2012-01-28
• [Presentation] 架橋剤の添加が義歯床用アクリルレジンの表面ぬれおよび曲げ強さに及ぼす影響 (2012)
  • Author(s): ディリヌル・マイマイティサウット, 洪光, 王維奇, 佐々木啓一
  • Organizer: 第4回日本義歯ケア学会学術大会
  • Place of Presentation: 長崎市
  • Year and Date: 2012-01-28
• [Presentation] Application of Sericin powder to the prosthetic materials (2011)
  • Author(s): G. Hong
  • Organizer: The 7th Congress of Chinese Dental Materials
  • Place of Presentation: 北京, 中国
  • Year and Date: 2011-12-12
• [Presentation] Application of Sericin powder to the prosthetic materials (2011)
  • Author(s): G.Hong
  • Organizer: The 7th Congress of Chinese Dental Materials
  • Place of Presentation: Beijing, China(招待講演)
  • Year and Date: 2011-12-12
• [Presentation] he influence of silicone remover on the peel bond strength of resilient denture liners to a denture base resin (2011)
  • Author(s): G. Hong, WQ. Wang, M. Dilinuer, H. Kanetaka, K. Sasaki
  • Organizer: AAP's 7th Biennial Meeting
  • Place of Presentation: 上海, 中国
  • Year and Date: 2011-10-29
• [Presentation] The influence of silicone remover on the peel bond strength of resilient denture liners to a denture base resin (2011)
  • Author(s): G.Hong, WQ.Wang, M.Dilinuer, H.Kanetaka, K.Sasaki
  • Organizer: AAP's 7th Biennial Meeting
  • Place of Presentation: Shanghai, China
  • Year and Date: 2011-10-29
• [Presentation] シトロフレックス可塑剤含有試作ティッシュコンディショナーの動的粘弾性について (2011)
  • Author(s): 王維奇, 洪光, ディリヌル・マイマイティサウット, 佐々木啓一
  • Organizer: 平成23年度日本補綴歯科学会東北・北海道支部、関越支部、東関東支部合同大会
  • Place of Presentation: 新潟
  • Year and Date: 2011-09-24
• [Presentation] シトロフレックス可塑剤含有試作ティッシュコンディショナーの動的粘弾性について (2011)
  • Author(s): 王維奇, 洪光, ディリヌル・マイマイティサウット, 佐々木啓一
  • Organizer: 平成23年度日本補綴歯科学会東北・北海道支部、関越支部、東関東支部合同大会
  • Place of Presentation: 新潟市
  • Year and Date: 2011-09-24
• [Presentation] Influence of sericin powder on the water absorption characteristics of tissue conditioners (2011)
  • Author(s): G. Hong, M. Dilinuer, K. Sasaki, T. Hamada, XY. Zhao
  • Organizer: International Dental Materials Congress 2011
  • Place of Presentation: ソウル, 韓国
  • Year and Date: 2011-05-28
• [Presentation] Influence of sericin powder on the water absorption characteristics of tissue conditioners (2011)
  • Author(s): G.Hong, M.Dilinuer, K.Sasaki, T.Hamada, XY.Zhao
  • Organizer: International Dental Materials Congress 2011
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2011-05-28
• [Presentation] クリームタイプ義歯安定剤および口腔内保湿剤の初期粘度および粘着強さ (2011)
  • Author(s): 洪光, ディリヌルマイマイティサウット1, 濱田泰三, 佐々木啓一
  • Organizer: 第120回日本補綴歯科学会学術大会
  • Place of Presentation: 広島
  • Year and Date: 2011-05-21
• [Presentation] 試作義歯床用アクリルレジンの曲げ強さおよび色調安定性について (2011)
  • Author(s): ディリヌル・マイマイティサウット, 洪光, 佐々木啓一, 濱田泰三
  • Organizer: 第120回日本補綴歯科学会学術大会
  • Place of Presentation: 広島
  • Year and Date: 2011-05-21
• [Presentation] クリームタイプ義歯安定剤および口腔内保湿剤の初期粘度および粘着強さ (2011)
  • Author(s): 洪光, ディリヌルマイマイティサウット, 濱田泰三, 佐々木啓一
  • Organizer: 第120回日本補綴歯科学会学術大会
  • Place of Presentation: 広島市
  • Year and Date: 2011-05-21
• [Presentation] 試作義歯床用アクリルレジンの曲げ強さおよび色調安定性について (2011)
  • Author(s): ディリヌル・マイマイティサウット, 洪光, 佐々木啓一, 濱田泰三
  • Organizer: 第120回日本補綴歯科学会学術大会
  • Place of Presentation: 広島市
  • Year and Date: 2011-05-21
• [Presentation] The latest progress of development of denture lining materials and the process of International Standardization (2010)
  • Author(s): G. Hong
  • Organizer: The 1st Global Congress of Chinese Dentists
  • Place of Presentation: 厦門、中国
  • Year and Date: 2010-12-03
• [Presentation] The latest progress of development of denture lining materials and the process of International Standardization (2010)
  • Author(s): G.Hong
  • Organizer: The 1st Global Congress of Chinese Dentists
  • Place of Presentation: Xia'men, China
  • Year and Date: 2010-12-03
• [Presentation] 義歯床用アクリルレジンの組成が親水性におよぼす影響 (2010)
  • Author(s): ディリヌルマイマイティサウット, 洪光, 佐々木啓一, 濱田泰三
  • Organizer: 平成22年度日本補綴歯科学会東北・北海道支部学術大会
  • Place of Presentation: 札幌
  • Year and Date: 2010-10-24
• [Presentation] 義歯床用アクリルレジンの組成が親水性におよぼす影響 (2010)
  • Author(s): ディリヌルマイマイティサウット, 洪光, 佐々木啓一, 濱田泰三
  • Organizer: 平成22年度日本補綴歯科学会 東北・北海道支部学術大会
  • Place of Presentation: 札幌
  • Year and Date: 2010-10-24
• [Presentation] セリシンパウダーがティッシュコンディショナーの表面ぬれおよび動的粘弾性に及ぼす影響 (2010)
  • Author(s): 洪光, ディリヌルマイマイティサウット, 濱田泰三, 佐々木啓一
  • Organizer: 第119回日本補綴歯科学会学術大会
  • Place of Presentation: 東京
  • Year and Date: 2010-06-12
• [Presentation] セリシンパウダーが試作粘膜調整材の動的粘弾性に及ぼす影響 (2010)
  • Author(s): 洪光, ディリヌルマイマイティサウット, 濱田泰三, 佐々木啓一
  • Organizer: セリシンパウダーが試作粘膜調整材の動的粘弾性に及ぼす影響
  • Place of Presentation: 東京
  • Year and Date: 2010-04-18
• [Presentation] セリシンパウダーが試作粘膜調整材の動的粘弾性に及ぼす影響 (2010)
  • Author(s): 洪光,ディリヌルマイマイティサウット, 濱田泰三, 佐々木啓一
  • Organizer: 第55回日本歯科理工学会学術講演会
  • Place of Presentation: 東京
  • Year and Date: 2010-04-18
• [Presentation] 試作ティッシュコンディショナーの表面ぬれについて (2009)
  • Author(s): 洪光, 濱田泰三
  • Organizer: 平成21年日本補綴歯科学会東北・北海道支部会
  • Place of Presentation: 盛岡
  • Year and Date: 2009-10-25
• [Presentation] Influence of Component on Viscoelasticity of Tissue Conditioner (2009)
  • Author(s): G. Hong, T. Hamada
  • Organizer: 2_<nd> Meeting of the IADR PAPF
  • Place of Presentation: 武漢, 中国
  • Year and Date: 2009-09-23
• [Presentation] Influence of Component on Viscoelasticity of Tissue Conditioner (2009)
  • Author(s): 洪光, 濱田泰三
  • Organizer: 2^<nd> Meeting of the IADR PAPF
  • Place of Presentation: 武漢・中国
  • Year and Date: 2009-09-23
• [Presentation] 試作クリームタイプ義歯安定剤の理工学的性質について (2009)
  • Author(s): 洪光, 濱田泰三
  • Organizer: 第55回東北大学歯学会
  • Place of Presentation: 仙台
  • Year and Date: 2009-06-26
• [Book] Interface Oral Health Science 2011 (2012)
  • Author(s): WQ Wang, G.Hong, M.Dilinuer, T.Hamada, K.Sasaki
  • Publisher: Springer
• [Book] Interface Oral Health Science 2011 (2012)
  • Author(s): M.Dilinuer, G.Hong, WQ Wang, T.Hamada, K.Sasaki
  • Publisher: Springer
• [Book] 義歯のケア-歯科衛生士のための副読本 (2010)
  • Author(s): 濱田泰三, 洪光, 村田比呂司, 水口俊介, 細井紀雄, 鈴木哲也
  • Publisher: デンタルダイヤモンド社東京
• [Book] 義歯のケア-歯科衛生士のための副読本 (2010)
  • Author(s): 濱田泰三, 洪光, 村田比呂司, 水口俊介, 細井紀雄, 鈴木哲也, ら
  • Publisher: デンタルダイヤモンド社