| Project/Area Number |
21791935
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | The Nippon Dental University |
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Principal Investigator |
HAGA Maiko The Nippon Dental University, 新潟生命歯学部, 助教 (60535219)
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| Project Period (FY) |
2009 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | インプラント / 骨結合 / 細胞・組織 / 歯学 |
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| Research Abstract |
The osteocytic function appears to be associated with bone remodeling. We have already reported histological aspects of bone remodeling around implants, which showed a chronological replacement of damaged immature bone into compact one. Based on these previous reports, this study aimed to examine histological alternation of osteocytes around implants during bone remodeling by using rats as model animals. The bone remodeling gradually replaced the irregular distribution of osteocytes in the immature bone at the early stage into the regular arrangement in the compact bone by 3 months after implantation. The results of this study on osteocytes and their molecules indicate that osteocytes would serve as a local regulator of bone remodeling around implants.
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