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A histological investigation of biological stability of the bone surrounding a titanium implant

Research Project

Project/Area Number 21791935
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Dental engineering/Regenerative dentistry
Research InstitutionThe Nippon Dental University

Principal Investigator

HAGA Maiko  The Nippon Dental University, 新潟生命歯学部, 助教 (60535219)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywordsインプラント / 骨結合 / 細胞・組織 / 歯学
Research Abstract

The osteocytic function appears to be associated with bone remodeling. We have already reported histological aspects of bone remodeling around implants, which showed a chronological replacement of damaged immature bone into compact one. Based on these previous reports, this study aimed to examine histological alternation of osteocytes around implants during bone remodeling by using rats as model animals. The bone remodeling gradually replaced the irregular distribution of osteocytes in the immature bone at the early stage into the regular arrangement in the compact bone by 3 months after implantation. The results of this study on osteocytes and their molecules indicate that osteocytes would serve as a local regulator of bone remodeling around implants.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (14 results)

All 2011 2010 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (12 results)

  • [Journal Article] A morphological analysis on the osteocytic lacunar canalicular system in bone surrounding dental implants2011

    • Author(s)
      Maiko Haga, Kayoko Nozawa-Inoue, Minqi Li, Kimimitsu Oda, Sumio Yoshie, Norio Amizuka, Takeyasu Maeda
    • Journal Title

      The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology 印刷中

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] A morphological analysis on the osteocytic lacunar canalicular system in bone surrounding dental implants

    • Author(s)
      Maiko Haga
    • Journal Title

      The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Histological alternation of osteocytes around dental implants2011

    • Author(s)
      羽下麻衣子, 野澤-井上佳世子, 李敏啓, 吉江紀夫, 網塚憲生, 前田健康
    • Organizer
      第88回日本生理学会大会/第116回日本解剖学会総会・全国学術集会合同大会(予定であったが、震災によりJournal of Physiological Sciences誌による誌上開催に変更)
    • Place of Presentation
      .
    • Year and Date
      2011-03-29
    • Related Report
      2010 Final Research Report
  • [Presentation] 歯科インプラント周囲における骨細胞・骨細管系の組織化学的変化2010

    • Author(s)
      羽下麻衣子, 野澤-井上佳世子, 李敏啓, 吉江紀夫, 網塚憲生, 前田健康
    • Organizer
      第52回歯科基礎医学会学術大会・総会
    • Place of Presentation
      タワーホール船堀,船堀
    • Year and Date
      2010-09-21
    • Related Report
      2010 Final Research Report
  • [Presentation] 歯科インプラント周囲における骨細胞・骨細管系の組織化学的変化2010

    • Author(s)
      羽下麻衣子
    • Organizer
      第52回歯科基礎医学会学術大会・総会
    • Place of Presentation
      タワーホール船堀, 船堀
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Property of Injured Bone around Implants Caused by Cavity Preparation2010

    • Author(s)
      Maiko Haga, Kayoko Nozawa-Inoue, Sumio Yoshie, Takeyasu Maeda
    • Organizer
      88th General Session and Exhibition of International Association for Dental Research
    • Place of Presentation
      Barcelona, Spain.
    • Year and Date
      2010-07-16
    • Related Report
      2010 Final Research Report
  • [Presentation] Property of Injured Bone around Implants Caused by Cavity Preparation2010

    • Author(s)
      Maiko Haga
    • Organizer
      88th General Session and Exhibition of International Association for Dental Research
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2010-07-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] 骨窩洞形成により傷害を受けた骨の性質2010

    • Author(s)
      羽下麻衣子, 野澤-井上佳世子, 吉江紀夫, 前田健康
    • Organizer
      第115回日本解剖学会総会・全国学術大会
    • Place of Presentation
      岩手県県民会館,岩手
    • Year and Date
      2010-03-30
    • Related Report
      2010 Final Research Report
  • [Presentation] 骨窩洞形成により傷害を受けた骨の性質2010

    • Author(s)
      羽下麻衣子
    • Organizer
      第115回日本解剖学会総会・全国学術集会
    • Place of Presentation
      岩手県民会館
    • Year and Date
      2010-03-30
    • Related Report
      2009 Annual Research Report
  • [Presentation] Long-term response of the bone to the titanium implant in the rat maxilla.2010

    • Author(s)
      Maiko Haga, Kayoko Nozawa-Inoue, Minqi Li, Sumio Yoshie, Norio Amizuka, Takeyasu Maeda
    • Organizer
      The 6th Congress of the Asian Academy of Osseointegration
    • Place of Presentation
      Seoul, Republic of Korea.
    • Related Report
      2010 Final Research Report
  • [Presentation] 歯科インプラント周囲骨の骨改造と骨細胞における組織化学的検索2010

    • Author(s)
      羽下麻衣子, 李敏啓, 吉江紀夫
    • Organizer
      第28回日本骨代謝学会学術集会
    • Place of Presentation
      京王プラザホテル,東京
    • Related Report
      2010 Final Research Report
  • [Presentation] Long-term response of the bone to the titanium implant in the rat maxilla2010

    • Author(s)
      Maiko Haga
    • Organizer
      The 6th Congress of the Asian Academy of Osseointegration
    • Place of Presentation
      Seoul, Republic of Korea
    • Related Report
      2010 Annual Research Report
  • [Presentation] 歯科インプラント周囲骨の骨改造と骨細胞における組織化学的検索2010

    • Author(s)
      羽下麻衣子
    • Organizer
      第28回日本骨代謝学会学術集会
    • Place of Presentation
      京王プラザホテル, 東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] Histological alternation of osteocytes around dental implants

    • Author(s)
      羽下麻衣子
    • Organizer
      第88回日本生理学会大会/第116回日本解剖学会総会・全国学術集会合同大会
    • Place of Presentation
      2011年3月29日予定であったが、震災にとりJournal of Physiological Sciences誌による誌上開催に変更
    • Related Report
      2010 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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