An fMRI study of the relationship mastication and brain function.

• Project/Area Number: 21792084
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Orthodontic/Pediatric dentistry
• Research Institution: Kyushu University
• Principal Investigator: YASUNAGA Atsushi Kyushu University, 大学病院, 医員 (80515990)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2009: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
• Keywords: 咬合 / fMRI / 歯列矯正 / PRIP / f MRI

Research Abstract

So far, people say and think that " Mastication"is good for proceed to keep memory and prevent for forgetfulness. And there are many reports which have revealed the part of activation when human masiticate. This time, based on these reports, our findings indicate that the physiological meaning of the part of teeth alighenment and the relationships between occlusion and brain function.

Research Products

• [Journal Article] PRIP分子を介したGABAA受容体のエンドサイトーシス調節機構の解明研究 (2007)
  • Author(s): 安永敦, 兼松隆, 平田雅人
  • Journal Title: 九州大学テーシス
• [Journal Article] Modulation of GABAA Receptor Phosphorylation and Membrane Trafficking by Phospholipase C-related Inactive Protein/Protein Phosphatase 1 and 2A Signaling Complex Underlying Brain-derived Neurotrophic Factor-dependent Regulation of GABAergic Inhibition (2006)
  • Author(s): Takashi Kanematsu, Atsushi Yasunaga, Yoshito Mizoguchi, Akiko Kuratani,Josef T.Kittler, Jasmina N.Jovanovic, Kei Takenaka, Keiichi I.Nakayama,Kiyoko Fukami, Tadaomi Takenawa, Stephen J.Moss, Junichi Nabekura, Masato Hirata
  • Journal Title: J.Biol.Chem. 281 Pages: 22180-22189
• [Journal Article] PRIP, a Ins(1,4,5)P3 binding protein, is a key molecule for GABAA receptor de-phosphorylation (2005)
  • Author(s): 安永敦, 兼松隆, 平田雅人
  • Journal Title: 第17回歯科基礎医学会大会
• [Journal Article] PRIP, a Ins(1,4,5)P3 binding protein, mediates GABAA receptor endocytosis, 4thJapan-Korea Conference on Signal Transduction for Young Scientists. (2005)
  • Author(s): Yasunaga A, Kanematsu T, Hirata M
  • Journal Title: Pohang, Korea
• [Journal Article] Alteration of BDNF-induced modulation of GABA signaling in hippocampal cell of PRIR-KO mice (2004)
  • Author(s): 兼松隆, 安永敦, 平田雅人
  • Journal Title: 第77回日本生化学会大会
• [Journal Article] Possible involvement of GABARAP in GABAA receptor cell surface expression, 3rd Japan-Korea Conference on Signal Transduction for Young Scientists. (2004)
  • Author(s): Yasunaga A,Terunuma M,Kanematsu T,Hirata M
  • Journal Title: Pohang, Korea