| Budget Amount *help |
¥2,808,000 (Direct Cost: ¥2,160,000、Indirect Cost: ¥648,000)
Fiscal Year 2010: ¥1,313,000 (Direct Cost: ¥1,010,000、Indirect Cost: ¥303,000)
Fiscal Year 2009: ¥1,495,000 (Direct Cost: ¥1,150,000、Indirect Cost: ¥345,000)
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| Research Abstract |
We found that sensory organs play important roles in life span regulation in the nematode C. elegans. We previously reported that intermittent fasting (IF), a kind of dietary restriction, extends the life span of C. elegans by more than 60%. We found that mutant strains with various defects in sensory organ development responded to IF to a lesser extent than wild type animals. The results show that sensory perception mediates IF-induced longevity.
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