Effect of periodontal treatment on oral indigenous microbiota

• Project/Area Number: 21890187
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Social dentistry
• Research Institution: Kyushu University
• Principal Investigator: TAKESHITA Toru Kyushu University, 歯学研究院, 助教 (50546471)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000); Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: 口腔フローラ / 16SrRNA / T-RFLP / 歯周治療 / 16S rRNA遺伝子 / 歯周炎 / SRP / FMD

Research Abstract

This investigation clarified that bacterial community structure in saliva is more similar to that of tongue coating rather than that of supragingival plaque. In addition, it revealed that bacterial community structure of saliva is stable in dental and periodontal treatment, while bacterial composition in supragingival plaque greatly alters. It is suggested that a novel treatment approach is needed for the improvement of bacterial community structure of saliva.

Research Products

• [Journal Article] Relationship between oral malodor and the global composition of indigenous bacterial populations in saliva. (2010)
  • Author(s): Takeshita T, Suzuki N, Nakano Y, Shimazaki Y, Yoneda M, Hirofuji T, Yamashita Y.
  • Journal Title: Appl Environ Microbiol 76 Pages: 2804-2814
  • Peer Reviewed
• [Journal Article] Relationship between oral malodor and the global composition of indigenous bacterial populations in saliva (2010)
  • Author(s): Takeshita T., et al.
  • Journal Title: Applied and Environmental Microbiology Volume: 76(9) Pages: 2806-2814
  • Peer Reviewed
• [Journal Article] Relationship between oral malodor and the global composition of indigenous bacterial populations in saliva (2010)
  • Author(s): Takeshita T, et al.
  • Journal Title: Applied and Environmental Microbiology 76(In press)
  • Peer Reviewed
• [Presentation] Tongue microbiota is disturbed in elderly adults fed by tube (2010)
  • Author(s): Takeshita, et al.
  • Organizer: 第58回国際歯科研究学会(JADR)総会・学術大会
  • Place of Presentation: 北九州市
  • Year and Date: 2010-11-21
• [Presentation] Sizing error in the T-RFLP analysis of 16S rRNA gene is dependent on the bacterial species. (2010)
  • Author(s): Takeshita T, Kishikawa S, Yamashita Y.
  • Organizer: International symposium of Microbial Ecology
  • Place of Presentation: Seattle,U.S.
  • Year and Date: 2010-08-23
• [Presentation] Sizing error in the T-RFLP analysis of 16S rRNA gene is dependent on the bacterial species (2010)
  • Author(s): Takeshita, et al.
  • Organizer: 13th International Symposium of Microbial Ecology
  • Place of Presentation: Seattle, US
  • Year and Date: 2010-08-23
• [Presentation] 唾液中に認められる細菌種の由来についての検討 (2010)
  • Author(s): 竹下徹、山中渉、山下喜久
  • Organizer: 第83回日本細菌学会総会
  • Place of Presentation: 横浜市
  • Year and Date: 2010-03-27
• [Presentation] 口腔フローラの構成の評価とその可能性 (2009)
  • Author(s): 竹下徹
  • Organizer: 口腔衛生学会
  • Place of Presentation: 岐阜
  • Year and Date: 2009-10-09