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Adaptations of the central nervous system and skeletal muscle following resistance training

Research Project

Project/Area Number 21H03335
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Review Section Basic Section 59020:Sports sciences-related
Research InstitutionRitsumeikan University

Principal Investigator

Maeo Sumiaki  立命館大学, スポーツ健康科学部, 助教 (60774586)

Co-Investigator(Kenkyū-buntansha) 金久 博昭  鹿屋体育大学, 学長, 学長 (50161188)
Project Period (FY) 2021-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000)
Fiscal Year 2023: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2022: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2021: ¥12,090,000 (Direct Cost: ¥9,300,000、Indirect Cost: ¥2,790,000)
Keywordsレジスタンストレーニング / 運動単位 / 高密度筋電図 / 筋力 / 筋量 / 筋線維 / 筋原線維 / 筋肥大 / 中枢神経系 / 骨格筋 / 動員数 / 皮下脂肪厚 / 筋横断面積 / 筋線維横断面積 / 伝導速度
Outline of Research at the Start

本研究では、神経・筋生理学分野における種々の研究手法、主に経頭蓋磁気刺激、高密度表面筋電図、筋バイオプシー法を用い、筋力トレーニングに伴う中枢神経系および骨格筋の適応を明らかにすることを目指す。より具体的には、トレーニングが皮質脊髄路の興奮性や抑制性、運動単位の振る舞い、ならびに筋線維や筋原線維の量・構造的特性に及ぼす影響を検証し、さらにそれらと筋力との関連性を明らかにすることを目的とする。

Outline of Final Research Achievements

This study examined potential adaptations of the central nervous system and skeletal muscle following resistance training by comparing long-term resistance trained and untrained individuals.
For the central nervous system, we used high-density surface electromyography (HD-sEMG) to investigate the influence of anatomical and neural factors on the quality of HD-sEMG signals, as well as motor unit behaviour during low/moderate muscle contractions and also during rapid contractions. For the skeletal muscle, we used MRI and muscle biopsy techniques to identify characteristics of whole muscle, muscle fibre, and myofibrils of resistance trained and untrained individuals. By combining the HD-sEMG and biopsy techniques, we also validated non-invasive estimation of muscle fibre size from HD-sEMG signals, more specifically from motor unit conduction velocity.

Academic Significance and Societal Importance of the Research Achievements

筋に抵抗をかけるレジスタンストレーニングは、筋量や筋力を高め、日常生活における生活の質やアスリートの運動パフォーマンスの向上に貢献する。本研究により、長期的にトレーニングを実施している鍛錬者と非鍛錬者の中枢神経系および骨格筋の特性の違いや、研究遂行上の方法論について、新たな知見が得られた。本研究の成果は、今後より直接的な縦断研究(トレーニング介入実験)を実施するうえで重要な情報となり、さらに、トレーニングやリハビリテーションの現場においても活用されるものとなると期待できる。

Report

(4 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Annual Research Report
  • 2021 Annual Research Report
  • Research Products

    (15 results)

All 2024 2023 2022 2021 Other

All Int'l Joint Research (10 results) Journal Article (5 results) (of which Int'l Joint Research: 5 results,  Peer Reviewed: 5 results,  Open Access: 3 results)

  • [Int'l Joint Research] Loughborough University/Imperial College London/Queen Mary University(英国)

    • Related Report
      2023 Annual Research Report
  • [Int'l Joint Research] University of Padua(イタリア)

    • Related Report
      2023 Annual Research Report
  • [Int'l Joint Research] University of Maryland/Louisiana State University(米国)

    • Related Report
      2023 Annual Research Report
  • [Int'l Joint Research] University of Maribor(スロベニア)

    • Related Report
      2023 Annual Research Report
  • [Int'l Joint Research] Friedrich-Alexander University(ドイツ)

    • Related Report
      2023 Annual Research Report
  • [Int'l Joint Research] Loughborough University/Imperial College London/Queen Mary University of London(英国)

    • Related Report
      2022 Annual Research Report
  • [Int'l Joint Research] Friedrich-Alexander-University(ドイツ)

    • Related Report
      2022 Annual Research Report
  • [Int'l Joint Research] University of Padua(イタリア)

    • Related Report
      2022 Annual Research Report
  • [Int'l Joint Research] University of Maryland(米国)

    • Related Report
      2022 Annual Research Report
  • [Int'l Joint Research] ラフバラ大学/インペリアル・カレッジ・ロンドン(英国)

    • Related Report
      2021 Annual Research Report
  • [Journal Article] Long-term resistance trained human muscles have more fibres, more myofibrils and tighter myofilament packing than untrained2024

    • Author(s)
      Sumiaki Maeo, Thomas G. Balshaw, Benjamin Marz, Zhaoxia Zhou, Bill Haug, Neil R. W. Martin, Nicola Maffulli, Jonathan P. Folland
    • Journal Title

      Medicine & Science in Sports & Exercise

      Volume: -

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Non‐invasive estimation of muscle fibre size from high‐density electromyography2023

    • Author(s)
      Casolo Andrea、Maeo Sumiaki、Balshaw Thomas G.、Lanza Marcel B.、Martin Neil R. W.、Nuccio Stefano、Moro Tatiana、Paoli Antonio、Felici Francesco、Maffulli Nicola、Eskofier Bjoern、Kinfe Thomas M.、Folland Jonathan P.、Farina Dario、Vecchio Alessandro Del
    • Journal Title

      The Journal of Physiology

      Volume: 601 Issue: 10 Pages: 1831-1850

    • DOI

      10.1113/jp284170

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Neural decoding from surface high-density EMG signals: influence of anatomy and synchronization on the number of identified motor units2022

    • Author(s)
      Oliveira Daniela Souza de、Casolo Andrea、Balshaw Thomas G、Maeo Sumiaki、Lanza Marcel Bahia、Martin Neil R W、Maffulli Nicola、Kinfe Thomas Mehari、Eskofier Bjoern M、Folland Jonathan P、Farina Dario、Del Vecchio Alessandro
    • Journal Title

      Journal of Neural Engineering

      Volume: 19 Issue: 4 Pages: 046029-046029

    • DOI

      10.1088/1741-2552/ac823d

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Neural adaptations to long-term resistance training: evidence for the confounding effect of muscle size on the interpretation of surface electromyography2021

    • Author(s)
      Skarabot Jakob、Balshaw Thomas G.、Maeo Sumiaki、Massey Garry J.、Lanza Marcel B.、Maden-Wilkinson Thomas M.、Folland Jonathan P.
    • Journal Title

      Journal of Applied Physiology

      Volume: 131 Issue: 2 Pages: 702-715

    • DOI

      10.1152/japplphysiol.00094.2021

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Behavior of motor units during submaximal isometric contractions in chronically strength-trained individuals2021

    • Author(s)
      Casolo Andrea、Del Vecchio Alessandro、Balshaw Thomas G.、Maeo Sumiaki、Lanza Marcel Bahia、Felici Francesco、Folland Jonathan P.、Farina Dario
    • Journal Title

      Journal of Applied Physiology

      Volume: 131 Issue: 5 Pages: 1584-1598

    • DOI

      10.1152/japplphysiol.00192.2021

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Int'l Joint Research

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Published: 2021-04-28   Modified: 2025-01-30  

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