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Control of Patho-Bruxism from Central Nervous system

Research Project

Project/Area Number 21K09989
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 57050:Prosthodontics-related
Research InstitutionNihon University

Principal Investigator

IIDA Takashi  日本大学, 松戸歯学部, 准教授 (50453882)

Co-Investigator(Kenkyū-buntansha) 牧山 康秀  日本大学, 松戸歯学部, 教授 (00219312)
小見山 道  日本大学, 松戸歯学部, 教授 (60339223)
Project Period (FY) 2021-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2023: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2022: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2021: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords睡眠時ブラキシズム / 覚醒時ブラキシズム / ウェアラブル筋電計 / 歯科補綴治療 / 経頭蓋磁気刺激法 / 経頭蓋直流刺激
Outline of Research at the Start

病的な睡眠時ブラキシズムは口腔顔面痛、咬合性外傷、失活歯の歯根破折、補綴装置の破壊といった歯科的問題を引き起こすリスクファクターとなる可能性が示唆されているが、その原因療法は解明されていない。本研究では、病的な睡眠時ブラキシズムに特異的な活動を示す中枢活動部位を同定し、その研究結果を基に中枢から病的な睡眠時ブラキシズムを制御する原因療法の確立を試みる。

Outline of Final Research Achievements

Main aim of this study was to make the novel therapy for bruxism considering central nervous system. The Epworth Sleepiness Scale (ESS), Pittsburgh Sleep Quality Index (PSQI), and awareness of awake bruxism as clarified via interviews were conducted on 34 participants as subjective evaluations. The EMG device was used to record left temporal muscle activity for 6.5 h and the number of awake bruxism episodes per hour. The participants were then classified into “bruxer” and “non-bruxer” groups based on the number of awake bruxism episodes.23% of the participants who reported having no awareness of awake bruxism in the interviews were defined as “bruxers” in the objective evaluations. In the bruxer group, positive correlations were found between the number of awake bruxism episodes and both ESS and PSQI scores.These findings suggest that sleep quality is a major risk factor for awake bruxism.

Academic Significance and Societal Importance of the Research Achievements

歯科補綴治療においてブラキシズム(歯ぎしり)がリスクファクターとなる患者はブラキシズムを習癖とする全ての患者ではなく,咬合性外傷,失活歯の歯根破折,補綴装置の破壊といった歯科的問題を引き起こす病的なブラキシズムを習癖として有する者である。この習癖に対する制御が可能となれば,歯科補綴治療はこれまで以上に良好な予後を導くことが可能になる。したがって,ブラキシズムに関する客観的評価を確立すること,病的なブラキシズムの診断基準を確立すること,そしてブラキシズムを抑制する治療方法が確立することは患者のQOLの向上,医療費の削減へとつながることが予想される。

Report

(4 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • Research Products

    (16 results)

All 2024 2023 2022 2021 Other

All Int'l Joint Research (2 results) Journal Article (5 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 5 results,  Open Access: 5 results) Presentation (9 results) (of which Int'l Joint Research: 5 results,  Invited: 1 results)

  • [Int'l Joint Research] Aarhus University(デンマーク)

    • Related Report
      2023 Annual Research Report
  • [Int'l Joint Research] オーフス大学歯学部(デンマーク)

    • Related Report
      2022 Research-status Report
  • [Journal Article] Analysis of definite awake bruxism using a portable electromyography device2024

    • Author(s)
      Yoshida Kazuhiro、Iida Takashi、Ishii Yuki、Komiyama Osamu
    • Journal Title

      Journal of Oral Science

      Volume: 66 Issue: 1 Pages: 66-69

    • DOI

      10.2334/josnusd.23-0362

    • ISSN
      1343-4934, 1880-4926
    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comparison of masticatory muscle activity between young adults and elderly participants using a novel standardized bite device2024

    • Author(s)
      Ishii Yuki、Iida Takashi、Honda-Sakaki Mika、Yoshida Kazuhiro、Svensson Peter、Komiyama Osamu
    • Journal Title

      Journal of Dentistry

      Volume: 143 Pages: 104887-104887

    • DOI

      10.1016/j.jdent.2024.104887

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effect of Sustained Jaw Opening on Fatigue, Pressure Pain Sensations, and Stiffness in the Masticatory Muscles2023

    • Author(s)
      Watanabe K, Iida T, Ishii Y, Yoshida K , Yamakawa Y, Hayakawa H, Komiyama O
    • Journal Title

      International Journal of Oral-Medical Sciences

      Volume: 21 Issue: 4 Pages: 131-136

    • DOI

      10.5466/ijoms.21.131

    • ISSN
      1347-9733, 2185-4254
    • Year and Date
      2023-04-10
    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of Sustained Jaw Opening on the Masseter Muscle in En­do­don­tic Patients in Whom Rubber Dam Dry Field Technique Was Used2023

    • Author(s)
      飯田 崇, 渡邉 航介, 石井 優貴, 吉田 一央, 岩﨑 正敏, 榊 実加, 小峯 千明, 神尾 直人, 岡部 達, 小見山 道
    • Journal Title

      Japanese Journal of Orofacial Pain

      Volume: 15 Issue: 1 Pages: 13-18

    • DOI

      10.11264/jjop.15.13

    • ISSN
      1882-9333, 1883-308X
    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Impact of oral motor task training on corticomotor pathways and diadochokinetic rates in young healthy participants.2022

    • Author(s)
      Boscato N, Hayakawa H, Iida T, Costa YM, Kothari SF, Kothari M, Svensson P.
    • Journal Title

      J Oral Rehabil.

      Volume: 49 Issue: 9 Pages: 924-934

    • DOI

      10.1111/joor.13349

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] Correlation between definite awake bruxism and stress using salivary biomarkers2024

    • Author(s)
      Oguro H, Iida T, Yoshida K, Ishii Y, Yamakawa Y, Ebashi A, Satoh K, Komiyama O
    • Organizer
      102nd General Session & Exhibition of the IADR
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Analysis of “Definite” Awake Bruxism Using a Portable Electromyography Device2024

    • Author(s)
      Yoshida K, Iida T, Ishii Y, Komiyama O
    • Organizer
      102nd General Session & Exhibition of the IADR
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Bruxism -a Problem in the Central Nervous System?-2023

    • Author(s)
      Iida T
    • Organizer
      101st General Session & Exhibition of the IADR
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 覚醒時ブラキシズムの日内変動に関する検討2022

    • Author(s)
      吉田一央,飯田 崇,石井優貴,早川英利,神山裕名,西森秀太,増田 学,小見山 道
    • Organizer
      公益社団法人 日本補綴歯科学会 第131回学術大会
    • Related Report
      2022 Research-status Report
  • [Presentation] ウェアラブル筋電計を用いた覚醒時ブラキシズムの客観的評価の検討-質問票による主観的評価と比較して-2022

    • Author(s)
      石井優貴、吉田一央,早川英利 、増田 学 、神山裕名、西森秀太、山本 泰、飯田 崇、内田貴之、小見山 道
    • Organizer
      第35回一般社団法人日本顎関節学会学術大会
    • Related Report
      2022 Research-status Report
  • [Presentation] 睡眠状態が覚醒時ブラキシズムの発現に及ぼす影響2022

    • Author(s)
      山川雄一郎,飯田崇,吉田一央,石井優貴,増田 学,榊実加,神山裕名,西森秀太,小峯千明,山本 泰,小見山 道
    • Organizer
      第27回日本口腔顔面痛学会学術大会
    • Related Report
      2022 Research-status Report
  • [Presentation] 支台歯形成時の持続した開口が咀嚼筋の疼痛閾値へ及ぼす影響2022

    • Author(s)
      渡辺航介,飯田 崇,早川英利,石井優貴,吉田一 央,生田真衣,神山裕名,小見山 道
    • Organizer
      令和4年度 公益社団法人日本補綴歯科学会 九州支部学術大会
    • Related Report
      2022 Research-status Report
  • [Presentation] Referred pain/sensations evoked by palpation on the temporal muscle2021

    • Author(s)
      Kazuhiro Yoshida, Hidetoshi Hayakawa, Manabu Masuda, Shellie Ann Boudreau, Takashi Iida, Peter Svensson, Osamu Komiyama
    • Organizer
      The 99th General Session of the IADR
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] Infulence of long-lasting jaw opening on the masseter muscle2021

    • Author(s)
      Yuki Ishii, Takashi Iida, Kazuhiro Yoshida, Hidetoshi Hayakawa, Antoon De Laat, Osamu komiyama
    • Organizer
      2021 Asian Academy of Orofacial Pain and Temporomandibular Disorder
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research

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Published: 2021-04-28   Modified: 2025-01-30  

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