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Creation of binding growth factors by molecular evolutionary engineering and their medical applications

Research Project

Project/Area Number 22220009
Research Category

Grant-in-Aid for Scientific Research (S)

Allocation TypeSingle-year Grants
Research Field Biomedical engineering/Biological material science
Research InstitutionThe Institute of Physical and Chemical Research

Principal Investigator

ITO Yoshihiro  独立行政法人理化学研究所, 伊藤ナノ医工学研究室, 主任研究員 (40192497)

Co-Investigator(Kenkyū-buntansha) TADA Seiichi  国立研究開発法人理化学研究所, 伊藤ナノ医工学研究室, 基礎科学特別研究員 (30598165)
UZAWA Takanori  国立研究開発法人理化学研究所, 伊藤ナノ医工学研究室, 専任研究員 (60554376)
UEDA Motoki  国立研究開発法人理化学研究所, 伊藤ナノ医工学研究室, 研究員 (10615040)
MATSUKAWA Akihiro  岡山大学, 医歯薬学総合研究科, 教授 (90264283)
YOSHIDA Yasuhiro  北海道大学, 歯学研究科, 教授 (90281162)
SAKURAGI Makoto  独立行政法人理化学研究所, 基幹研究所, 基礎科学特別研究員 (10435828)
KITAJIMA Takashi  独立行政法人理化学研究所, 伊藤ナノ医工学研究室, 協力研究員 (40399556)
Project Period (FY) 2010-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥217,880,000 (Direct Cost: ¥167,600,000、Indirect Cost: ¥50,280,000)
Fiscal Year 2014: ¥43,160,000 (Direct Cost: ¥33,200,000、Indirect Cost: ¥9,960,000)
Fiscal Year 2013: ¥42,640,000 (Direct Cost: ¥32,800,000、Indirect Cost: ¥9,840,000)
Fiscal Year 2012: ¥42,640,000 (Direct Cost: ¥32,800,000、Indirect Cost: ¥9,840,000)
Fiscal Year 2011: ¥41,340,000 (Direct Cost: ¥31,800,000、Indirect Cost: ¥9,540,000)
Fiscal Year 2010: ¥48,100,000 (Direct Cost: ¥37,000,000、Indirect Cost: ¥11,100,000)
Keywords進化分子工学 / 成長因子 / 結合性 / 融合タンパク質 / バイオマテリアル / タンパク質工学 / 再生医療 / バイオ直交化学 / 試験管内進化法 / 固定化
Outline of Final Research Achievements

The concept of growth factor immobilization from Japan was confirmed by not only chemical immobilization, but also design of binding growth factor and extended from biological tissue or organic materials to metal or inorganic materials. For the creation of binding growth factors not only conventional recombinant gene method but also bioorthogonal chemistry, molecular evolutionary engineering, or the fused method was developed. The prepared binding growth factors were applied for direct injection or with substrate for implantation into animals and the effects were confirmed for future regenerative medicine. The developed methodology is also universally applicable for creation of novel functional molecules.

Assessment Rating
Verification Result (Rating)

A-

Assessment Rating
Result (Rating)

A-: Progress in the research is steadily towards the initial goal. However, further efforts are necessary as a part of the research progress is delayed.

Report

(9 results)
  • 2015 Research Progress Assessment (Verification Result) ( PDF )
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Annual Research Report   Abstract(Research Progress Assessment) ( PDF )   Research Progress Assessment (Result) ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (203 results)

All 2015 2014 2013 2012 2011 2010 Other

All Journal Article (73 results) (of which Peer Reviewed: 70 results,  Acknowledgement Compliant: 8 results,  Open Access: 3 results) Presentation (113 results) (of which Invited: 52 results) Book (16 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] In vitro selection of a photoresponsive peptide aptamer to glutathione-immobilized microbeads2015

    • Author(s)
      Seiichi Tada, Qingmin Zang, Wei Wang, Masuki Kawamoto, Mingzhe Liu, Michiru Iwashita, Takanori Uzawa, Daisuke Kiga, Masayuki Yamamura, and Yoshihiro Ito
    • Journal Title

      J. Biosci. Bioeng.

      Volume: 119 Issue: 2 Pages: 137-139

    • DOI

      10.1016/j.jbiosc.2014.06.018

    • NAID

      110009922573

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] In vitro selection of a peptide aptamer that changes fluorescence in response to verotoxin2015

    • Author(s)
      Yasodha Manandhar, Tara Bahadur K.C., Wei Wang, Takanori Uzawa, Toshiro Aigaki, and Yoshihiro Ito
    • Journal Title

      Biotechnol. Lett.

      Volume: 37 Issue: 3 Pages: 619-625

    • DOI

      10.1007/s10529-014-1719-7

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Chemically fixed autologous feeder cell-derived niche for human induced pluripotent stem cell culture2015

    • Author(s)
      Binata Joddar, Chieko Nishioka, Eiki Takahashi, and Yoshihiro Ito
    • Journal Title

      J. Mater. Chem. B.

      Volume: 3 Issue: 11 Pages: 2301-2307

    • DOI

      10.1039/c4tb01635a

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Solubilization of Single-Walled Carbon Nanotubes using a Peptide Aptamer in Water below Critical Micelle Concentration2015

    • Author(s)
      Zha Li, Tomoshi Kameda, Takashi Isoshima, Eiry Kobatake, Takeshi Tanaka, Yoshihiro Ito, and Masuki Kawamoto
    • Journal Title

      Langmuir

      Volume: 31 Issue: 11 Pages: 3482-3488

    • DOI

      10.1021/la504777b

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] The significance of membrane fluidity of feeder cell-derived substrates for maintenance of iPS cell stemness2015

    • Author(s)
      Yue Zhou, Hongli Mao, Binata Joddar, Nobuhisa Umeki, Yasushi Sako, Ken-Ichi Wada, Chieko Nishioka, Eiki Takahashi, Yi Wang, and Yoshihiro Ito
    • Journal Title

      Sci. Rep.

      Volume: 印刷中

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Effects of ROCK inhibitor Y-27632 on cell fusion through a microslit2015

    • Author(s)
      Ken-Ichi Wada, Kazuo Hosokawa, Yoshihiro Ito, and Mizuo Maeda
    • Journal Title

      Bioeng. Biotechnol.

      Volume: 印刷中

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Nanolayer formation on titanium by phosphonated gelatin for cell adhesion and growth enhancement2015

    • Author(s)
      Xiaoyue Zhou, Shin-Hye Park, Hongli Mao, Takashi Isoshima, Yi Wang, and Yoshihiro Ito
    • Journal Title

      Int. J. Nanomed.

      Volume: 印刷中

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] In vitro selection of a peptide aptamer that potentiates inhibition of cyclin-dependent kinase 2 by purvalanol2014

    • Author(s)
      Wei Wang, Yoshinori Hirano, Takanori Uzawa, Mingzhe Liu, Makoto Taiji and Yoshihiro Ito
    • Journal Title

      Med. Chem. Commun.

      Volume: 5 Issue: 9 Pages: 1400-1403

    • DOI

      10.1039/c4md00142g

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] A novel, visible light-induced, rapidly cross-linkable gelatin scaffold for osteochondral tissue engineering2014

    • Author(s)
      Tetsuro Mazaki, Yasuyuki Shiozaki, Kentaro Yamane, Aki Yoshida, Mariko Nakamura, Yasuhiro Yoshida, Di Zhou, Takashi Kitajima, Masato Tanaka, Yoshihiro ito, Toshifumi Ozaki, and Akihiro Matsukawa
    • Journal Title

      Sci. Rep.

      Volume: 4 Issue: 1 Pages: 4457-4457

    • DOI

      10.1038/srep04457

    • NAID

      120005526619

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mussel-inspired human gelatin nano-coating for creating biologically adhesive surface2014

    • Author(s)
      Xi Yang, Liping Zhu, Seiichi Tada, Di Zhou, Takashi Kitajima, Takashi Isoshima, Yasuhiro Yoshida, Mari Nakamura, Weiqun Yan, and Yoshihiro Ito
    • Journal Title

      Int. J. Nanomed.

      Volume: 印刷中

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cell fusion through a microslit between adhered cells and observation of their nuclear behavior2014

    • Author(s)
      Ken-Ichi Wada, Eitaro Kondo, Kazuo Hosokawa, Yoshihiro Ito, and Mizuo Maeda
    • Journal Title

      Biotechnol. Bioeng.

      Volume: 印刷中

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Direct in vitro selection of titanium-binding epidermal growth factor2014

    • Author(s)
      Seiichi Tada, Emel Timucin, Takashi Kitajima, Osman Ugur Sezerman, and Yoshihiro Ito
    • Journal Title

      Biomaterials

      Volume: 35 Issue: 11 Pages: 3497-3503

    • DOI

      10.1016/j.biomaterials.2014.01.010

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A fluorogenic peptide probe developed by in vitro selection using tRNA carrying a fluorogenic amino acid2014

    • Author(s)
      Wei Wang, Takanori Uzawa, Naoya Tochio, Jumpei Hamatsu, Yoshinori Hirano, Seiichi Tada, Hisao Saneyoshi, Takanori Kigawa, Nobuhiro Hayashi, Yutaka Ito, Makoto Taiji, Toshiro Aigaki, and Yoshihiro Ito
    • Journal Title

      Chem Commun.

      Volume: 50 Issue: 22 Pages: 2962-2964

    • DOI

      10.1039/c3cc47624c

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phosphorylated gelatin to enhance cell adhesion to titanium2014

    • Author(s)
      Shin-Hye Park, Liping Zhu, Seiichi Tada, Sei Obuse, Yasuhiro Yoshida, Mariko Nakamura, Tae Il Son, Satoshi Tsuneda, and Yoshihiro Ito
    • Journal Title

      Polym. Int.

      Volume: 印刷中

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Regeneration effect of visible-light curing furfuryl alginate compound by release of epidermal growth factor for wound healing application2014

    • Author(s)
      Yun Heo, Hyung-Jae Lee, Eun-Hye Kim, Mi-Kyung Kim, Yoshihiro Ito, and Tae-Il Son
    • Journal Title

      J. Appl. Polym. Chem.

      Volume: 印刷中

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vitro and in vivo enhanced osteogenesis by kaempferol found by a high-throughput assay using human mesenchymal stromal cells2014

    • Author(s)
      Tetsuro Mazaki, Takashi Kitajima, Yasuyuki Shiozaki, Miwa Sato, Megumi Mino, Aki Yoshida, Mariko Nakamura, Yasuhiro Yoshida, Masato Tanaka, Toshifumi Ozaki, Akihiro Matsukawa and Yoshihiro Ito
    • Journal Title

      J. Func. Foods

      Volume: 6 Pages: 241-247

    • DOI

      10.1016/j.jff.2013.10.013

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vitro selection of peptide aptamers using a ribosome display for a conducting polymer2014

    • Author(s)
      Zha Li, Takanori Uzawa, Haichao Zhao, Shyh-Chyang Luo, Hsiao-hua Yu, Eiry Kobatake, and Yoshihiro Ito
    • Journal Title

      J. Biosci. Bioeng.

      Volume: 117 Issue: 4 Pages: 501-503

    • DOI

      10.1016/j.jbiosc.2013.10.005

    • NAID

      110009817067

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preparation and in vivo evaluation of photo-cured O-carboxymethyl chitosan micro-particle for controlled drug delivery2014

    • Author(s)
      Yun Heo, Shin-Hye Park, Si-Yoong Seo, Ju-Young Yun, Yoshihiro Ito, and Tae-Il Son
    • Journal Title

      Macro. Res.

      Volume: 印刷中

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The immobilization of bone morphogenetic protein-2 via photo curable azidophenyl hyaluronic acid on a titanium surface and providing effect for cell differentiation2014

    • Author(s)
      Hyung-Jae Lee, Yun Heo, Kyung-Tai Park, Eun-Hye Kim, Yoshihiro Ito, Kwang-Sup Song, Dong-Keun Han, and Tae-Il Son
    • Journal Title

      Macro. Res.

      Volume: 22(2) Issue: 2 Pages: 173-178

    • DOI

      10.1007/s13233-014-2032-y

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Visible light-curable polymers for biomedical applications2014

    • Author(s)
      Di Zhou and Yoshihiro Ito
    • Journal Title

      Sci. China Chem.

      Volume: 57 Issue: 4 Pages: 510-521

    • DOI

      10.1007/s11426-014-5069-z

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] いよいよ化学の出番がきた進化分子工学―機能性を付与した分子認識を自由自在にデザイン2014

    • Author(s)
      多田誠一、鵜澤尊規、伊藤嘉浩
    • Journal Title

      化学

      Volume: 69 Pages: 70-71

    • Related Report
      2013 Annual Research Report
  • [Journal Article] Immobilization of bone morphogenetic protein on DOPA- or dopamine-treated titanium surfaces to enhance osseointegration2013

    • Author(s)
      Jeonghwa Kang, Seiichi Tada, Takashi Kitajima, Tae Il Son, Toshiro Aigaki and Yoshihiro Ito
    • Journal Title

      BioMed Res. Intern.

      Volume: 265980 Pages: 265980-265980

    • DOI

      10.1155/2013/265980

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An epidermal growth factor derivative with binding affinity for hydroxyapatite and titanium surfaces2013

    • Author(s)
      Jeonghwa Kang, Seiichi Tada, Makoto Sakuragi, Hiroshi Abe, Reiko Ito, Junko Ishikawa, Shino Kurata, Takashi Kitajima, Tae Il Son, Toshiro Aigaki, and Yoshihiro Ito
    • Journal Title

      Biomaterials

      Volume: 34 Issue: 38 Pages: 9747-9753

    • DOI

      10.1016/j.biomaterials.2013.09.004

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Spatial gradients of chemotropic factors from immobilized patterns to guide axonal growth and regeneration2013

    • Author(s)
      Binata Joddar, Adam T. Guy, Hiroyuki Kamiguchi, and Yoshihiro Ito
    • Journal Title

      Biomaterials

      Volume: 34 Issue: 37 Pages: 9593-9601

    • DOI

      10.1016/j.biomaterials.2013.08.019

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Bio-orthogonal and combinatorial approaches for design of binding growth factors2013

    • Author(s)
      Yoshihiro Ito and Seiichi Tada
    • Journal Title

      Biomaterials

      Volume: 34 Issue: 31 Pages: 7565-7574

    • DOI

      10.1016/j.biomaterials.2013.06.037

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Artificial niche substrates for embryonic and induced pluripotent stem cell cultures2013

    • Author(s)
      Binata Joddar and Yoshihiro Ito
    • Journal Title

      Biotechnol. J.

      Volume: 166 Issue: 2 Pages: 218-228

    • DOI

      10.1016/j.jbiotec.2013.04.021

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enhanced in vivo osteogenesis by nanocarrier-fused BMP42013

    • Author(s)
      Y. Shiozaki
    • Journal Title

      Int. J. Nanomed.

      Volume: 8 Pages: 1349-1360

    • DOI

      10.2147/ijn.s44124

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preparation of photocured azidophenyl-fish gelatin and its capturing of human epidermal growth factor on titanium plate2013

    • Author(s)
      S.-H. Park
    • Journal Title

      J. Appl. Polym. Sci.

      Volume: 127 Issue: 1 Pages: 154-160

    • DOI

      10.1002/app.37854

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Coating of titanium plate by photo-curable azidophenyl chitosan derivative for application to implants2013

    • Author(s)
      S.-Y. Seo
    • Journal Title

      J. Appl. Polym. Sci.

      Volume: 128 Issue: 6 Pages: 4322-4326

    • DOI

      10.1002/app.38478

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Sustained delivery of siRNA from dopamine-coated stainless steel surfaces2013

    • Author(s)
      B. Joddar
    • Journal Title

      Acta Biomat.

      Volume: 9 Issue: 5 Pages: 6753-6761

    • DOI

      10.1016/j.actbio.2013.01.007

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cationic cholesterol-modified gelatin as an in vitro siRNA delivery vehicle2013

    • Author(s)
      P. A. Kadengodlu
    • Journal Title

      Mol. BioSyst.

      Volume: 9 Issue: 5 Pages: 965-968

    • DOI

      10.1039/c2mb25424g

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preparation of photoreactive azidophenyl hyaluronic acid derivative: protein immobilization for medical applications2013

    • Author(s)
      H.-J. Lee
    • Journal Title

      Macro. Res.

      Volume: 21 Issue: 2 Pages: 216-220

    • DOI

      10.1007/s13233-013-1016-7

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Flavonol-containing phosphorylated pullulan may attenuate pulp inflammation2013

    • Author(s)
      J. Yonehiro
    • Journal Title

      Int. Endod. J.

      Volume: 46 Issue: 2 Pages: 119-127

    • DOI

      10.1111/j.1365-2591.2012.02095.x

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vitro selection of peptide aptamers with affinity to single-wall carbon nanotubes using a ribosome display2013

    • Author(s)
      Z. Li
    • Journal Title

      Biotechnol. Lett.

      Volume: 35 Issue: 1 Pages: 39-45

    • DOI

      10.1007/s10529-012-1049-6

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Visible light-induced crosslinkable gelatin for direct pulp capping2013

    • Author(s)
      M. Nakamura
    • Journal Title

      Key Eng. Mater.

      Volume: - Pages: 543-546

    • DOI

      10.4028/www.scientific.net/kem.529-530.543

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phosphorylated pullulan bioadhesive for regeneration and reconstruction of bone and tooth2013

    • Author(s)
      Y, Yoshida
    • Journal Title

      Key Eng. Mater.

      Volume: - Pages: 516-521

    • DOI

      10.4028/www.scientific.net/kem.529-530.516

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inorganic material surfaces made bioactive by immobilizing growth factors for hard tissue engineering2013

    • Author(s)
      D. Zhou
    • Journal Title

      RSC Adv.

      Volume: 掲載確定 Issue: 28 Pages: 11095-11095

    • DOI

      10.1039/c3ra23313h

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expansion of Aptamer Library from “Natural soup” to “Unnatural soup”2013

    • Author(s)
      T. Uzawa
    • Journal Title

      Chem. Commun.

      Volume: 49 Issue: 18 Pages: 1786-1795

    • DOI

      10.1039/c2cc36348h

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vitro selection of a photo-responsive peptide aptamer by ribosome display2012

    • Author(s)
      Mingzhe Liu, Seiichi Tada, Mika Ito, Hiroshi Abe, and Yoshihiro Ito
    • Journal Title

      Chemical Communication

      Volume: 48 Issue: 97 Pages: 11871-11873

    • DOI

      10.1039/c2cc36618e

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Immobilization of epidermal growth factor on titanium and stainless steel surfaces via dopamine treatment"2012

    • Author(s)
      J. Kang
    • Journal Title

      Mater. Sci. Eng. C

      Volume: 32 Issue: 8 Pages: 2552-2561

    • DOI

      10.1016/j.msec.2012.07.039

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Establishment of ex vivo pulpitis model by co-culturing immortalized dental pulp cells and macrophages2012

    • Author(s)
      J. Yonehiro
    • Journal Title

      Int. Endod. J.

      Volume: 45 Issue: 12 Pages: 1103-1108

    • DOI

      10.1111/j.1365-2591.2012.02074.x

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genetic PEGylation2012

    • Author(s)
      S. Tada
    • Journal Title

      PLoS ONE

      Volume: - Issue: 11 Pages: e49235-e49235

    • DOI

      10.1371/journal.pone.0049235

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Positively charged cholesterol–recombinant human gelatins foster the cellular uptake of proteins and murine immune reactions2012

    • Author(s)
      P. A. Kadengodlu
    • Journal Title

      Int. J. Nanomed.

      Volume: 7 Pages: 5437-5450

    • DOI

      10.2147/ijn.s36350

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Spatial immobilization of bone morphogenetic protein-4 in a collagen-PLGA hybrid scaffold for enhanced osteoinductivity2012

    • Author(s)
      H. Lu
    • Journal Title

      Biomaterials

      Volume: 33 Issue: 26 Pages: 6140-6146

    • DOI

      10.1016/j.biomaterials.2012.05.038

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Osteoblast compatibility of materials depends on serum protein absorbability in osteogenesis2012

    • Author(s)
      Kenichi Harimoto, Yasuhiro Yoshida, Kumiko Yoshihara, Noriyuki Nagaoka, Takuya Matsumoto, Yoh-ichi Tagawa
    • Journal Title

      Dental Materials Journal

      Volume: 31 Issue: 4 Pages: 674-680

    • DOI

      10.4012/dmj.2012-075

    • NAID

      10030501890

    • ISSN
      0287-4547, 1881-1361
    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preparation of low-crystalline apatite nanoparticles and their coating onto quartz substrates2012

    • Author(s)
      M. Kawashita
    • Journal Title

      J. Mater. Sci. Mater. Med.

      Volume: 23 Issue: 6 Pages: 1355-1362

    • DOI

      10.1007/s10856-012-4614-6

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Feeder cells support the culture of induced pluripotent stem cells even after chemical fixation2012

    • Author(s)
      X.-S. Yue
    • Journal Title

      PLoS ONE

      Volume: 7 Issue: 3 Pages: e32707-e32707

    • DOI

      10.1371/journal.pone.0032707

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Self-assembled Nano-layering at the Adhesive Interface2012

    • Author(s)
      Y.Yoshida
    • Journal Title

      Journal of Dental Research

      Volume: 91 Issue: 4 Pages: 376-381

    • DOI

      10.1177/0022034512437375

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Visible light-induced photocurable (forming a film) low molecular weight chitosan derivatives for biomedical applications: Synthesis, characterization and in vitro biocompatibility2012

    • Author(s)
      S. Y. Seo
    • Journal Title

      J. Ind. Eng. Chem.

      Volume: 18 Issue: 4 Pages: 1258-1262

    • DOI

      10.1016/j.jiec.2012.01.006

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Real time assessment of surface interactions with a titanium passivation layerby surface plasmon resonance2012

    • Author(s)
      Hirata, I., Yoshida, Y., et al
    • Journal Title

      Acta Biomaterialia

      Volume: 8 Issue: 3 Pages: 1260-1266

    • DOI

      10.1016/j.actbio.2011.11.025

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Design and synthesis of binding growth factors2012

    • Author(s)
      S. Tada
    • Journal Title

      Int. J. Mol. Sci.

      Volume: 13 Issue: 5 Pages: 6053-6072

    • DOI

      10.3390/ijms13056053

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Elaborate synthesis of biological macromolecules2012

    • Author(s)
      Y. Ito
    • Journal Title

      ChemBioChem

      Volume: 13 Issue: 8 Pages: 1100-1102

    • DOI

      10.1002/cbic.201200183

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 結合性細胞増殖因子の創成と応用2012

    • Author(s)
      北嶋隆
    • Journal Title

      高分子論文集

      Volume: 69 Pages: 1-10

    • NAID

      10030170305

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 接着と合着を再考する―歯質接着のためのナノ界面分析―2012

    • Author(s)
      吉田靖弘
    • Journal Title

      日本補綴歯科学会誌

      Volume: 4 Pages: 353-363

    • NAID

      10031123456

    • Related Report
      2012 Annual Research Report
  • [Journal Article] Chemical analyses in dental adhesive technology2012

    • Author(s)
      Y. Yoshida
    • Journal Title

      Jpn. Dent. Sci. Rev.

      Volume: 48 Issue: 2 Pages: 141-152

    • DOI

      10.1016/j.jdsr.2012.03.001

    • NAID

      10030957910

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 生体材料は高齢者の健康維持にどのように貢献できるか2012

    • Author(s)
      吉田靖弘
    • Journal Title

      老年歯科医学

      Volume: 26 Pages: 387-393

    • NAID

      10031137175

    • Related Report
      2012 Annual Research Report
  • [Journal Article] The effects of covalently immobilized hyaluronic acid substrates on the adhesion, expansion, and differentiation of embryonic stem cells for in vitro tissue engineering2011

    • Author(s)
      Binata Joddar, Takashi Kitajima, Yoshihiro Ito
    • Journal Title

      Biomaterials

      Volume: 32 Issue: 33 Pages: 8404-8415

    • DOI

      10.1016/j.biomaterials.2011.07.083

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Polypeptide aptamer selection using a stabilized ribosome display2011

    • Author(s)
      Wei Wang, Shuta Hara, Mingzhe Liu, Toshiro Aigaki, Shigeru Shimizu, Yoshihiro Ito
    • Journal Title

      J.Biosci.Bioeng.

      Volume: 112(5) Issue: 5 Pages: 515-517

    • DOI

      10.1016/j.jbiosc.2011.07.011

    • NAID

      110008761519

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Recombinant hBMP4 incorporated with non-canonical amino acid for binding to hydroxyapatite2011

    • Author(s)
      Makoto Sakuragi, Takashi Kitajima, Teruyuki Nagamune, Yoshihiro Ito
    • Journal Title

      Biotechnol.Lett.

      Volume: 33 Issue: 9 Pages: 1885-1890

    • DOI

      10.1007/s10529-011-0637-1

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Eecombinant human gelatin substitute with photoreactive properties for cell culture and tissue engineering2011

    • Author(s)
      Takashi Kitajima, Sei Obuse, Takahiro Adachi, Masahiro Tomita, Yoshihiro Ito
    • Journal Title

      Biotechnol.Bioeng.

      Volume: 108(10) Issue: 10 Pages: 2468-2476

    • DOI

      10.1002/bit.23192

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preparation of a visible light-reactive low molecular-O-carboxymethyl chitosan (LM-O-CMCS) derivative and applicability as an anti-adhesion agent2011

    • Author(s)
      Shin-hye Park, Si-yoong Seo, Ha-na Na, Kwang-il Kim, Jea-woo Lee, Hee-dong Woo, Jue-hee Lee, Hyun-kwang Seok, Jae-gwan Lee, Sang-in Chung, KyuHwan Chung, DongKeun Han, Yoshihiro Ito, Eui-chang Jang, Tae-il Son
    • Journal Title

      Macromol.Res.

      Volume: 19(9) Issue: 9 Pages: 921-927

    • DOI

      10.1007/s13233-011-0914-9

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Addition of the collagen biding domain of fibronectin potentiates the biochemical stability of hepatocyte growth factor for cutaneous wound healing2011

    • Author(s)
      Naoko Okiyama, Takashi Kitajima, Yoshihiro Ito, Hiroo Yokozaki, Nobuyuki Miyasaka, Hitoshi Kohsaka
    • Journal Title

      J.Dermatol.Sci.

      Volume: 61(3) Issue: 3 Pages: 215-217

    • DOI

      10.1016/j.jdermsci.2011.01.001

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Biological Modifications of Materials Surfaces with Proteins for Regenerative Medicine2011

    • Author(s)
      Binata Joddar, Yoshihiro Ito
    • Journal Title

      J.Mater.Chem.

      Volume: 21 Issue: 36 Pages: 13737-13755

    • DOI

      10.1039/c1jm10984g

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Creation of Polymer Catalysts by Molecular Evolutionary Engineering and Hybridization of Biocatalysts2011

    • Author(s)
      劉明哲、阿部洋、伊藤嘉浩
    • Journal Title

      KOBUNSHI RONBUNSHU

      Volume: 68 Issue: 7 Pages: 405-416

    • DOI

      10.1295/koron.68.405

    • NAID

      130004489332

    • ISSN
      0386-2186, 1881-5685
    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nano-layering of phosphoric-acid ester monomer at enamel and dentin2011

    • Author(s)
      Yoshihara, K., Yoshida, Y., et al
    • Journal Title

      Acta Biomaterialia

      Volume: 7 Issue: 8 Pages: 3187-3195

    • DOI

      10.1016/j.actbio.2011.04.026

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Detection of synthetic RGDS (PO3H2) PA peptide adsorption using a titanium surface plasmon resonance (SPR) biosensor2011

    • Author(s)
      Abe, Y., Hiasa, K., Hirata, I., Okazaki, Y., Nogami, K., Mizumachi, W., Yoshida, Y., Suzuki, K., Okazaki, M., Akagawa, Y.
    • Journal Title

      Journal of Materials Science : Materials in Medicine

      Volume: 22 Issue: 3 Pages: 657-661

    • DOI

      10.1007/s10856-010-4222-2

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nano-layering of phosphoric-acid ester monomer at enamel and dentin2011

    • Author(s)
      Yoshihara, K., Yoshida, Y., et al
    • Journal Title

      Journal of Dental Research

      Volume: 90 Issue: 5 Pages: 602-606

    • DOI

      10.1177/0022034510397197

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Addition of the collagen binding domain of fibronectin potentiates the biochemical stablaity of hepatocyte growth factor for cutaneous wound healing2011

    • Author(s)
      N.Okiyama, T.Kitajima, Y.Ito, H.Yokozaki, N.Miyasaka, H.Kohsaka
    • Journal Title

      J.Dermatol.Sci.

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis of O-carboxylated low molecular chitosan with azido phenyl group : Its application for adhesion prevention2010

    • Author(s)
      H.-N.Na, K.-I., Kim, J.-H.Han, J.-G., Lee, D.-J.Han, Y.Ito, K.-S.Song, E.-C.Japng, T.-I.Son
    • Journal Title

      Macro.Res.

      Volume: 18 Pages: 1001-1007

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Visible-light-induced cross-linkable gelatin2010

    • Author(s)
      T.I.Son, M.Sakuragi, S.Takahashi, S, Obuse, J.Kang, M.Fijishiro, H.Matsushita, J.Gong, S.Shimidzu, Y.Tajima, Y.Yoshida, K.Suzuki, T.Yamamoto, M.Nakamura, Y.Ito
    • Journal Title

      Acta Biomat.

      Volume: 10 Pages: 4005-4010

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Construction of fusion protein N-cadherin-Fc as an artificial extracellular matrix for maintenance of stem cell features2010

    • Author(s)
      X.-s.Yue, Y.Murakami, T.Tamai, M.Nagaoka, C.-S.Cho, Y.Ito, T.Akaike
    • Journal Title

      Biomaterials

      Volume: 31 Pages: 5287-5296

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preparation of photo-reactive azidophenyl chitosan derivative for immobilization of growth factors2010

    • Author(s)
      K.-I.Kin, J.-W.Lee, J.-H.Kang, K.-S.Song, E.-C.Jang, Y.Ito, T.-I.Son
    • Journal Title

      J.Appl.Polym.Sci.

      Volume: 117 Pages: 3029-3037

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reprogramming of somatic cells induced by fusion of embryonic stem cells using hemagglutinating virus of Japan envelope(HVJ-E)2010

    • Author(s)
      X.-s.Yue, M.Fijishira, M.Toyoda, T.Akaike, Y.Ito
    • Journal Title

      Biophys.Bioche.Res.Commun.

      Volume: 394 Pages: 1053-1057

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Bioconjugation towards bioactive materials for tissue engineering and biological devices2015

    • Author(s)
      Yoshihiro Ito
    • Organizer
      ACES Electromaterials Symposium 2015
    • Place of Presentation
      Wollongong AUSTRALIA
    • Year and Date
      2015-02-09 – 2015-02-14
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Engineered bone morphogenetic protein for hard tissue engineering2015

    • Author(s)
      Yoshihiro Ito
    • Organizer
      BTE2015
    • Place of Presentation
      Changchun, China
    • Year and Date
      2015-01-24 – 2015-01-25
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 進化分子工学による機能性分子認識の創成2015

    • Author(s)
      伊藤嘉浩
    • Organizer
      高分子学会 埼玉地区懇話会
    • Place of Presentation
      埼玉県さいたま市埼玉大学
    • Year and Date
      2015-01-16
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Molecular evolutionary Engineering for Creation of Functionally Molecular Recognizable Peptides2014

    • Author(s)
      Yoshihiro Ito
    • Organizer
      CEMSupra 2014
    • Place of Presentation
      Manza, Gumma, Japan
    • Year and Date
      2014-12-14 – 2014-12-16
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Molecular Evolutionary Engineering for Creation of Functional Peptides2014

    • Author(s)
      Yoshihiro Ito
    • Organizer
      ICSS Meeting
    • Place of Presentation
      Hong Kong, China
    • Year and Date
      2014-12-07 – 2014-12-11
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 非コードアミノ酸の導入による増殖因子の無機材料表面への固定化2014

    • Author(s)
      多田誠一、姜廷和、周小越、Zhu Liping, 伊藤嘉浩
    • Organizer
      第36回日本バイオマテリアル学会大会
    • Place of Presentation
      東京都江戸川区タワーホール船堀
    • Year and Date
      2014-11-18
    • Related Report
      2014 Annual Research Report
  • [Presentation] Regenerative medicine using biomaterials2014

    • Author(s)
      Yoshihiro Ito
    • Organizer
      Seminar at Jilin University
    • Place of Presentation
      Changchun, China
    • Year and Date
      2014-11-15
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Tissue engineering using growth factors2014

    • Author(s)
      Yoshihiro Ito
    • Organizer
      Seminar at Changchun Institute of Applied Chemistry, Chinese Academy Sciences
    • Place of Presentation
      Changchun, China
    • Year and Date
      2014-11-14
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Design and synthesis of binding growth factors2014

    • Author(s)
      Yoshihiro Ito
    • Organizer
      WCPRM2014
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2014-11-04 – 2014-11-08
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 進化分子工学の化学的拡張による機能性分子の創出2014

    • Author(s)
      伊藤嘉浩
    • Organizer
      阪大・CEMSジョイントセミナー
    • Place of Presentation
      大阪市大阪大学中之島センター
    • Year and Date
      2014-10-16 – 2014-10-17
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Engineered bone morphogenetic protein for hard tissue engineering2014

    • Author(s)
      Yoshihiro Ito
    • Organizer
      韓国中央大学校医学部セミナー
    • Place of Presentation
      ソウル、韓国
    • Year and Date
      2014-10-10
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Design of Biofunctional Peptides by Bio-orthogonal In Vitro Selection2014

    • Author(s)
      Yoshihiro Ito
    • Organizer
      韓国中央大学校生命科学院セミナー
    • Place of Presentation
      ソウル、韓国
    • Year and Date
      2014-10-09
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Design of Biofunctional Peptides by Bio-orthogonal In Vitro Selection2014

    • Author(s)
      Yoshihiro Ito
    • Organizer
      韓国高分子学会
    • Place of Presentation
      済州島、韓国
    • Year and Date
      2014-10-07 – 2014-10-08
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Phosphorylated gelatin to enhance cell adhesion to titanium2014

    • Author(s)
      Shin-Hye Park, Liping Zhu, Seiichi Tada, Satoshi Tsuneda, and Yoshihiro Ito
    • Organizer
      The Polymer Society of Korea : 2014 Annual Fall Meeting
    • Place of Presentation
      Jeju,Korea
    • Year and Date
      2014-10-07 – 2014-10-08
    • Related Report
      2014 Annual Research Report
  • [Presentation] Culture of iPS cells on chemically fixed feeder cells2014

    • Author(s)
      Yoshihiro Ito
    • Organizer
      TERMIS-AP
    • Place of Presentation
      Daegu, Korea
    • Year and Date
      2014-09-23 – 2014-09-28
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Direct selection of titanium-binding epidermal growth factor by evolutionary molecular engineering2014

    • Author(s)
      Seiichi Tada, Takashi Kitajima, Yoshihiro Ito
    • Organizer
      2014 Tissue Engineering and Regenerative Medicine International Society-Asia Pacific Meeting (TERMIS-AP 2014)
    • Place of Presentation
      Daegu, Korea
    • Year and Date
      2014-09-23 – 2014-09-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] Direct selection of titanium-binding growth factor by ribosome display2014

    • Author(s)
      Seiichi Tada, Takashi Kitajima, Yoshihiro Ito
    • Organizer
      The IUMRS International Conference in Asia 2014
    • Place of Presentation
      福岡県福岡市福岡大学
    • Year and Date
      2014-08-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] Design of Binding Proteins for Medical Applications2014

    • Author(s)
      Yoshihiro ito
    • Organizer
      PEM2014
    • Place of Presentation
      Kunming CHINA
    • Year and Date
      2014-08-23 – 2014-08-26
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Creation of functional peptides using bioorthogonal evolution2014

    • Author(s)
      Seiichi Tada and Yoshihiro Ito
    • Organizer
      248th ACS National Meeting & Expo
    • Place of Presentation
      San Francisco, CA, USA
    • Year and Date
      2014-08-10
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] チタン表面結合性ペプチドを用いた増殖因子の固定化2014

    • Author(s)
      多田誠一、北嶋隆、伊藤嘉浩
    • Organizer
      第43回医用高分子シンポジウム
    • Place of Presentation
      東京都江東区産業技術総合研究所 臨海副都心センター
    • Year and Date
      2014-07-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] Phosphorylated gelatin to enhance cell adhesion to titanium2014

    • Author(s)
      Shin-Hye Park, Liping Zhu, Seiichi Tada, Satoshi Tsuneda, and Yoshihiro Ito
    • Organizer
      Macro 2014
    • Place of Presentation
      Chiang Mai, THAILAND
    • Year and Date
      2014-07-06 – 2014-07-11
    • Related Report
      2014 Annual Research Report
  • [Presentation] Stem cell culture using cell-derived substrates2014

    • Author(s)
      Yoshihiro Ito
    • Organizer
      TERMIS EU
    • Place of Presentation
      Genova ITALY
    • Year and Date
      2014-06-10 – 2014-06-15
    • Related Report
      2014 Annual Research Report
  • [Presentation] Design of binding epidermal growth factors2014

    • Author(s)
      Yoshihiro Ito
    • Organizer
      TERMIS EU
    • Place of Presentation
      Genova ITALY
    • Year and Date
      2014-06-10 – 2014-06-15
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Mussel-inspired biological surface modification toward bioactive materials2014

    • Author(s)
      Yoshihiro Ito
    • Organizer
      2014 Materials Research Society of Korea
    • Place of Presentation
      Changwon KOREA
    • Year and Date
      2014-05-15 – 2014-05-16
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Molecular evolutionary engineering using expanded library from a “natural soup” to an “unnatural soup”2014

    • Author(s)
      Yoshihiro Ito
    • Organizer
      Seminar at Beijing University
    • Place of Presentation
      Beijing CHINA
    • Year and Date
      2014-04-18
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Biomaterials for medical engineering2014

    • Author(s)
      Yoshihiro Ito
    • Organizer
      Seminar at Tsinghua University
    • Place of Presentation
      Beijing, China
    • Year and Date
      2014-04-17
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Molecular evolutionary engineering using expanded library from a “natural soup” to an “unnatural soup”2014

    • Author(s)
      Yoshihiro Ito
    • Organizer
      Seminar at Chinese Academy of Sciences
    • Place of Presentation
      Beijing CHINA
    • Year and Date
      2014-04-16
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Phosphorylated gelatin to enhance cell adhesion to titanium2013

    • Author(s)
      Park Shinhye
    • Organizer
      The screening asia
    • Place of Presentation
      Biopolis street, Singapore
    • Related Report
      2013 Annual Research Report
  • [Presentation] Phosphorylated gelatin to enhance cell adhesion to titanium2013

    • Author(s)
      Park Shinhye
    • Organizer
      Annual meeting of japanese society of biomaterials
    • Place of Presentation
      Funabori, Tokyo, Japan
    • Related Report
      2013 Annual Research Report
  • [Presentation] Culture of mouse miPS on chemically fixed feeder cells: importance of membrane proteins diffusion2013

    • Author(s)
      Yue.Zhou
    • Organizer
      CEMS International Symposium on Supramolecular Chemistry and Functional Materials
    • Place of Presentation
      Tokyo, Japan
    • Related Report
      2013 Annual Research Report
  • [Presentation] Culture of mouse miPS on chemically fixed feeder cells2013

    • Author(s)
      Yue. Zhou
    • Organizer
      35th Japanese Conference on Biomaterials
    • Place of Presentation
      Funabori, Tokyo
    • Related Report
      2013 Annual Research Report
  • [Presentation] Culture of mouse miPS on chemically fixed feeder cells2013

    • Author(s)
      Yue. Zhou
    • Organizer
      Noyori Summer School
    • Place of Presentation
      神戸
    • Related Report
      2013 Annual Research Report
  • [Presentation] Dopamine-gelatin conjugate used to modify the surface of titanium2013

    • Author(s)
      Xi Yang
    • Organizer
      Noyori summer school
    • Place of Presentation
      神戸
    • Related Report
      2013 Annual Research Report
  • [Presentation] Dopamine-gelatin conjugate used to modify the surface of titanium2013

    • Author(s)
      Xi Yang
    • Organizer
      The 35th Annual Meeting of the Japanese Society for Biomaterials
    • Place of Presentation
      Funabori, Tokyo
    • Related Report
      2013 Annual Research Report
  • [Presentation] Bioorthogonal Protein Design in Combination with Directed Evolution for Biomaterials2013

    • Author(s)
      Ito Yoshihiro
    • Organizer
      Seminar at National Central University
    • Place of Presentation
      Taoyuan, Taiwan
    • Related Report
      2012 Annual Research Report
  • [Presentation] Bioorthogonal evolution for functionalized molecular recognition2013

    • Author(s)
      Ito Yoshihiro
    • Organizer
      Canada Japan Nanotechnology Workshop 2013
    • Place of Presentation
      Tokyo, Japan
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Bioorthogonal Protein Design in Combination with Directed Evolution for Biomaterials2013

    • Author(s)
      Ito Yoshihiro
    • Organizer
      The 4th Taiwan-Japan Symposium on Nanomedicine
    • Place of Presentation
      Taipei, Taiwan
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Materials Nanointerfaces for Regenerative Medicine and Tissue Engineeering2012

    • Author(s)
      Ito Yoshihiro
    • Organizer
      NAMIC, 2012
    • Place of Presentation
      Tehran, Iran
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Evolutionary molecular engineering for designing biomaterials2012

    • Author(s)
      Ito Yoshihiro
    • Organizer
      Seminar at Sabanci University
    • Place of Presentation
      Istanbul, Turkey
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Synthesis of cholesteroyl-gelatin for vaccine or siRNA delivery2012

    • Author(s)
      Ito Yoshihiro
    • Organizer
      9th World Biomaterial Congress
    • Place of Presentation
      Chengdu, China
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Immobilizaion of BMP on inorganic surface2012

    • Author(s)
      Kang Jeonghwa
    • Organizer
      第41 回医用高分子シンポジウム
    • Place of Presentation
      東京, 日本
    • Related Report
      2012 Annual Research Report
  • [Presentation] Design of titanium-binding epidermal growth factor by evolutionary molecular engineering2012

    • Author(s)
      Tada Seiichi
    • Organizer
      9th World Biomaterials Congress
    • Place of Presentation
      Chengdu, China
    • Related Report
      2012 Annual Research Report
  • [Presentation] Induction of antigen-specific immunity by pH-sensitive carbonate apatite particles2012

    • Author(s)
      Tada Seiichi
    • Organizer
      9th World Biomaterials Congress
    • Place of Presentation
      Chengdu, China
    • Related Report
      2012 Annual Research Report
  • [Presentation] Immobilization of growth factors on titanium, stainless steel, or hydroxyapatite2012

    • Author(s)
      Ito Yoshihiro
    • Organizer
      9th World Biomaterials Congress
    • Place of Presentation
      Chengdu, China
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Design and synthesis of photoreactive biopolymers2012

    • Author(s)
      Ito Yoshihiro
    • Organizer
      244th ACS National Meeting
    • Place of Presentation
      Philadelphia, USA
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Evolutionary molecular engineering for designing biomaterials2012

    • Author(s)
      Ito Yoshihiro
    • Organizer
      The 1st international symposium on polymer ecomaterials
    • Place of Presentation
      Changchun, China
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Microarray Diagnosis Using Photo-Immobilization2012

    • Author(s)
      Ito Yoshihiro
    • Organizer
      Seminar at Changchun Institute of Applied Chemistry
    • Place of Presentation
      Changchun, China
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Evolutionary molecular engineering for designing biomaterials2012

    • Author(s)
      Ito Yoshihiro
    • Organizer
      Seminar at Shenyang Pharmaceutical University
    • Place of Presentation
      Shenyang, China
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Design of Binding Growth Factors for Regenerative Medicine2012

    • Author(s)
      Ito Yoshihiro
    • Organizer
      Seminar at Jilin University
    • Place of Presentation
      Changchun, China
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Evolutionary molecular engineering for designing biomaterials2012

    • Author(s)
      Ito Yoshihiro
    • Organizer
      Seminar at USDA
    • Place of Presentation
      Wyndmoor, USA
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] in silico およびナノ粒子を用いた新しい牛白血病ワクチン開発2012

    • Author(s)
      竹嶋 伸之輔
    • Organizer
      動物用ワクチン‐バイオ医薬品研究会
    • Place of Presentation
      盛岡市, 日本
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 炭酸アパタイトを用いた抗原導入による免疫誘導2012

    • Author(s)
      多田 誠一
    • Organizer
      第21回日本組織適合性学会大会
    • Place of Presentation
      東京, 日本
    • Related Report
      2012 Annual Research Report
  • [Presentation] Synthesis of positively and negatively charged cholesterol-recombinant human gelatins for the cellular uptake of proteins and immune reactions2012

    • Author(s)
      Kadengodlu Ananda Pallavi
    • Organizer
      第21回日本組織適合性学会大会
    • Place of Presentation
      東京, 日本
    • Related Report
      2012 Annual Research Report
  • [Presentation] ph応答性ポリマー修飾リポソームによる抗原特異的細胞性・液性免疫の誘導2012

    • Author(s)
      弓場 英司
    • Organizer
      第21回日本組織適合性学会大会
    • Place of Presentation
      東京, 日本
    • Related Report
      2012 Annual Research Report
  • [Presentation] 細胞増殖因子の金属材料表面への固定化2012

    • Author(s)
      多田 誠一
    • Organizer
      第61回高分子討論会
    • Place of Presentation
      名古屋, 日本
    • Related Report
      2012 Annual Research Report
  • [Presentation] Synthesis of positively and negatively charged cholesterol-recombinant human gelatins for the cellular uptake of proteins and immune reactions2012

    • Author(s)
      Kadengodlu Pallavi Ananda
    • Organizer
      Japanese Society for histocompatibility and Immunogenetics
    • Place of Presentation
      Tokyo, 日本
    • Related Report
      2012 Annual Research Report
  • [Presentation] Synthesis of positively and negatively charged cholesterol-recombinant human gelatins for the cellular uptake of proteins and immune reactions2012

    • Author(s)
      Kadengodlu Pallavi Ananda
    • Organizer
      Noyori Summer School
    • Place of Presentation
      Matsue, Japan
    • Related Report
      2012 Annual Research Report
  • [Presentation] Fluorescence Titration for finding the binding sites of Peptide Aptamers on Calmodulin2012

    • Author(s)
      Manandhar Yasodha
    • Organizer
      第50回日本生物物理学会年会
    • Place of Presentation
      名古屋, 日本
    • Related Report
      2012 Annual Research Report
  • [Presentation] In vitro selection of peptide aptamers to single-wall carbon nanotubes2012

    • Author(s)
      Li Zha
    • Organizer
      第61回高分子討論会
    • Place of Presentation
      金沢, 日本
    • Related Report
      2012 Annual Research Report
  • [Presentation] In vitro selection of signaling peptide aptamers2012

    • Author(s)
      Wang Wei
    • Organizer
      第6回バイオ関連化学シンポジウム
    • Place of Presentation
      札幌, 日本
    • Related Report
      2012 Annual Research Report
  • [Presentation] Feeder cells support the culture of induced pluripotent stem cells even after chemical fixation2012

    • Author(s)
      Ito Yoshihiro
    • Organizer
      15th International Biotechnology Symposium 2012
    • Place of Presentation
      Daegu, Korea
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Immobilization of growth factors on inorganic materials2012

    • Author(s)
      Ito Yoshihiro
    • Organizer
      Biointerface 2012
    • Place of Presentation
      Dublin, Ireland
    • Related Report
      2012 Annual Research Report
  • [Presentation] Manipulation of individual live cells by micro-fabricated structure2012

    • Author(s)
      Wada Ken-Ichi
    • Organizer
      The 7th Sweden-Japan BaioNano Workshop
    • Place of Presentation
      Stockholm, Sweden
    • Related Report
      2012 Annual Research Report
  • [Presentation] 家兎骨軟骨欠損モデルにおける可視光硬化ゼラチンの骨軟骨組織修復の効果2012

    • Author(s)
      馬﨑 哲朗
    • Organizer
      日本バイオマテリアル学会シンポジウム2012
    • Place of Presentation
      仙台, 日本
    • Related Report
      2012 Annual Research Report
  • [Presentation] Molecular evolutionary engineering for design of biomaterials2012

    • Author(s)
      Ito Yoshihiro
    • Organizer
      2nd RIKEN=KFU workshop
    • Place of Presentation
      Kazan, Russia
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Automated microarray diagnosis2012

    • Author(s)
      Ito Yoshihiro
    • Organizer
      Postgenome 2012
    • Place of Presentation
      Kazan, Russia
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] ルテニウム錯体に結合するRNAアプタ マーの選出2012

    • Author(s)
      鵜澤 尊規
    • Organizer
      新学術領域第一回公開シンポジウム
    • Place of Presentation
      大岡山, 日本
    • Related Report
      2012 Annual Research Report
  • [Presentation] A signaling peptide aptamers2012

    • Author(s)
      W.Wang, T.Uzawa, T.Aigaki, Y.Ito
    • Organizer
      Gordon Research Conferences "Peptides as signals, BioMaterials and Therapeutics
    • Place of Presentation
      Ventura, CA., USA
    • Related Report
      2011 Annual Research Report
  • [Presentation] Photo-reactive biopolymers for medical applications2011

    • Author(s)
      Ito Yoshihiro
    • Organizer
      21th Fall Meeting of the Korean Society for Chitin and Chitosan Seoul Korea
    • Place of Presentation
      Seoul Korea(招待講演)
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] Design of biological surfaces for regenerative medicine2011

    • Author(s)
      Ito Yoshihiro
    • Organizer
      Seminar at Korean Institute of Science and Technology
    • Place of Presentation
      Seoul Korea(招待講演)
    • Year and Date
      2011-11-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] 無機材料の表面へのBMPの固定2011

    • Author(s)
      姜廷和, 櫻木誠, 多田誠一, 北嶋隆, 伊藤嘉浩
    • Organizer
      第33回日本バイオマテリアル学会
    • Place of Presentation
      京都
    • Year and Date
      2011-11-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 進化分子工学的手法を用いた化チタン表面へのEGFの固定化2011

    • Author(s)
      多田誠一, 北嶋隆, 伊藤嘉浩
    • Organizer
      第33回日本バイオマテリアル学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-11-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] Peptide aptamer to carbon nanotubes by ribosome display2011

    • Author(s)
      Z.Li, T.Uzawa, Y.Ito
    • Organizer
      60th symposium on macromolecules
    • Place of Presentation
      Okayama
    • Year and Date
      2011-09-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] A fluorescent sensor peptide aptamer by molecular evolutionary engineering2011

    • Author(s)
      W.Wang, T.Uzawa, T.Aigaki, Y.Ito
    • Organizer
      60th symposium on macromolecules
    • Place of Presentation
      Okayama
    • Year and Date
      2011-09-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] Immobilization of growth factor on inorganic surfaces2011

    • Author(s)
      姜廷和, 阿部洋, 北嶋隆, 相垣敏郎, 伊藤嘉浩
    • Organizer
      第40回医用高分子シンポジウムプログラム
    • Place of Presentation
      吹田
    • Year and Date
      2011-07-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] 無細胞翻訳系による長鎖PEGの部位特異的導入2011

    • Author(s)
      多田誠一, 伊藤嘉浩
    • Organizer
      第40回医用高分子シンポジウムプログラム
    • Place of Presentation
      吹田
    • Year and Date
      2011-07-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] リボソームディスプレイ法による酸化チタン結合性ペプチド融合EGFの創製2011

    • Author(s)
      多田誠一, 北嶋隆, 伊藤嘉浩
    • Organizer
      第60回高分子学会年次大会
    • Place of Presentation
      大阪
    • Year and Date
      2011-05-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] Design of biological surfaces for regenerative medicine2011

    • Author(s)
      Ito Yoshihiro
    • Organizer
      Seminar at Northwestern University
    • Place of Presentation
      Evanston USA(招待講演)
    • Year and Date
      2011-04-18
    • Related Report
      2011 Annual Research Report
  • [Presentation] 無機材料結合性成長因子EGFの創成2011

    • Author(s)
      姜廷和、櫻木誠、北嶋隆、相垣敏郎、伊藤嘉浩
    • Organizer
      第10回日本再生医療学会
    • Place of Presentation
      東京
    • Year and Date
      2011-03-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] Biomaterial Design Using Immobilization of Growth Factors2011

    • Author(s)
      Ito Yoshihiro
    • Organizer
      10th China-Japan-Korea Foresight Joint Symposium on Gene Delivery and International Symposium on Biomaterials 2011
    • Place of Presentation
      Guilin China(招待講演)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Immobilization of epidermal growth factor on titanium2011

    • Author(s)
      Ito Yoshihiro
    • Organizer
      2011 Annual Meeting and Exposition
    • Place of Presentation
      Orland USA
    • Related Report
      2011 Annual Research Report
  • [Presentation] Design of biological surfaces for regenerative medicine2011

    • Author(s)
      Ito Yoshihiro
    • Organizer
      Seminar at South China Normal University
    • Place of Presentation
      Guangzhou China(招待講演)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 無機・金属材料上への成長因子固定化2010

    • Author(s)
      伊藤嘉浩、姜廷和、櫻木誠、阿部洋、北嶋隆
    • Organizer
      第32回日本バイオマテリアル学会大会
    • Place of Presentation
      広島
    • Year and Date
      2010-11-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] バイオものづくりとしての合成生物学2010

    • Author(s)
      伊藤嘉浩
    • Organizer
      第11回「遺伝と変化」懇話会
    • Place of Presentation
      長崎
    • Year and Date
      2010-10-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] Design of biological surfaces for regenerative medicine2010

    • Author(s)
      Yoshihiro Ito
    • Organizer
      Seminar in Northeast Normal University
    • Place of Presentation
      長春(China)
    • Year and Date
      2010-10-12
    • Related Report
      2010 Annual Research Report
  • [Presentation] Design of biological surfaces for regenerative medicine2010

    • Author(s)
      Yoshihiro Ito
    • Organizer
      Seminar in Chinese Academy of Science
    • Place of Presentation
      長春(China)
    • Year and Date
      2010-10-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] 金属・無機表面への成長因子の固定化による生体機能性付与2010

    • Author(s)
      伊藤嘉浩、姜廷和、櫻木誠、阿部洋、北嶋隆
    • Organizer
      第59回高分子討論会
    • Place of Presentation
      札幌
    • Year and Date
      2010-09-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] Covalent immobilization of EGF on dopamine-modiiied metal surfaces2010

    • Author(s)
      姜廷和、櫻木誠、阿部洋、北嶋隆、相垣敏郎、伊藤嘉浩
    • Organizer
      日本化学会第4回関東支部大会
    • Place of Presentation
      つくば
    • Year and Date
      2010-08-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] Preparation of photo-curable human gelatin for cell culture matrix2010

    • Author(s)
      北嶋隆、小布施聖、Kadengodlu Pallavi Ananda、伊藤嘉浩
    • Organizer
      日本化学会第4回関東支部大会
    • Place of Presentation
      つくば
    • Year and Date
      2010-08-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] 無機・金属材料への成長因子固定化の試み2010

    • Author(s)
      姜廷和、阿部祥子、北嶋隆、櫻木誠、和田章、阿部洋、伊藤嘉浩
    • Organizer
      第39回医用高分子シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2010-07-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] Photo -crosslinkable polymers for cell cultures and microarrys

    • Author(s)
      伊藤 嘉浩
    • Organizer
      ICMAT2013
    • Place of Presentation
      シンガポール
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Cell manipulation by micro-fabricated device and stem cell culture

    • Author(s)
      伊藤 嘉浩
    • Organizer
      International Institute of Avian Conservation Science
    • Place of Presentation
      UAE Dubai
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Bioorthogonal and combinatorial approaches to design functional proteins and peptides

    • Author(s)
      伊藤 嘉浩
    • Organizer
      ChinaNANO2013
    • Place of Presentation
      中国 北京
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Bioorthogonal and combinatorial approaches to design functional proteins and peptides

    • Author(s)
      伊藤 嘉浩
    • Organizer
      北京大学
    • Place of Presentation
      中国 北京
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Bio-Orthogonal And Combinatorial Designs Of Binding Growth Factors

    • Author(s)
      伊藤 嘉浩
    • Organizer
      IABS2013
    • Place of Presentation
      中国 長春
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 進化分子工学の新展開

    • Author(s)
      伊藤 嘉浩
    • Organizer
      第86回日本生化学会フォーラム
    • Place of Presentation
      横浜パシフィコ
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Cell manipulation by micro-fabricated device and stem cell culture

    • Author(s)
      伊藤 嘉浩
    • Organizer
      Shanghai Institute of Ceramics, Chinese Academy of Sciences
    • Place of Presentation
      中国 上海
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Design of binding growth factors for tissue engineering

    • Author(s)
      伊藤 嘉浩
    • Organizer
      TERMIS-AP 2013
    • Place of Presentation
      中国 Wuzhen
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Photo-Reactive Polymers for Medical Applications

    • Author(s)
      伊藤 嘉浩
    • Organizer
      Changshu Institute of Technology
    • Place of Presentation
      中国 Suzhou
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] バイオ直交化学と進化分子工学を駆使したタンパク質工学の新潮流

    • Author(s)
      伊藤 嘉浩
    • Organizer
      第30回医用高分子研究会講座
    • Place of Presentation
      東大・生産研
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Engineered bone morphogenetic protein for hard tissue engineering

    • Author(s)
      伊藤 嘉浩
    • Organizer
      China Medical University
    • Place of Presentation
      台湾 台中
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Engineered bone morphogenetic protein for hard tissue engineering

    • Author(s)
      伊藤 嘉浩
    • Organizer
      台湾高分子学会
    • Place of Presentation
      台湾 台中
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Bio-orthogonal and combinatorial designs of functional proteins

    • Author(s)
      伊藤 嘉浩
    • Organizer
      ISAJ 4th Symposium India-Japan Symposium on Emerging Materials for Health, Environment and Safety
    • Place of Presentation
      東京、インド大使館
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Protein engineering for nano-surface modification towards bioactive materials

    • Author(s)
      伊藤 嘉浩
    • Organizer
      ICNS5
    • Place of Presentation
      イラン Kish island
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Protein Engineering for Biomaterials Science

    • Author(s)
      伊藤 嘉浩
    • Organizer
      韓国 慶北大学
    • Place of Presentation
      韓国 慶北大学(Daegu)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Ribosome display selection of epidermal growth factor binding to titanium surface

    • Author(s)
      Seiichi TADA, Takashi Kitajima, Yoshihiro Ito
    • Organizer
      第62回高分子学会年次大会
    • Place of Presentation
      京都
    • Related Report
      2013 Annual Research Report
  • [Presentation] バイオ直交化学と進化分子工学による固定化型増殖因子の創製

    • Author(s)
      多田誠一、北嶋隆、伊藤嘉浩
    • Organizer
      第62回高分子討論会
    • Place of Presentation
      金沢
    • Related Report
      2013 Annual Research Report
  • [Presentation] チタン表面結合性上皮増殖因子のリボソームディスプレイ法を用いた選別

    • Author(s)
      多田誠一、北嶋隆、伊藤嘉浩
    • Organizer
      第35回日本バイオマテリアル学会大会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] Design of a photo-responsive peptide aptamer containing an azobenzene residue by in vitro selection

    • Author(s)
      Seiichi Tada, Qingmin Zang, Wei Wang, Mingzhe Liu, Yoshihiro Ito
    • Organizer
      CEMS International Symposium on Supramolecular Chemistry and Functional Materials 2013
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] Phosphorylated gelatin to enhance cell adhesion to titanium

    • Author(s)
      Park Shinhye
    • Organizer
      Biophysical society conference or the Biomaterial conference
    • Place of Presentation
      和光、埼玉
    • Related Report
      2013 Annual Research Report
  • [Presentation] Design and production of DOPA-containing VEGF.

    • Author(s)
      Takashi Kitajima, Yang-Xi, Kenichi Wada, Yan Weigun, Yoshihiro Ito
    • Organizer
      35th Conference of Japanese Society for Biomaterials.
    • Place of Presentation
      Tokyo, Japan
    • Related Report
      2013 Annual Research Report
  • [Presentation] Dopamine-gelatin conjugate used to modify the surface of titanium

    • Author(s)
      Xi Yang
    • Organizer
      Biophysical society conference or the Biomaterial conference
    • Place of Presentation
      Wako, Japan
    • Related Report
      2013 Annual Research Report
  • [Presentation] Bioorthogonal and combinatorial approaches to design functional proteins and peptides

    • Author(s)
      伊藤 嘉浩
    • Organizer
      NAMIC2013
    • Place of Presentation
      IRAN Esfahan
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Book] “Creation of functional peptides by evolutionary engineering with bioorthogonal incorporation of artificial components”, in "Green Polymer Chemistry III: Biobased Materials and Biocatalysis", ed. by H. N. Cheng, R. A. Gross, and P. B. Smith, ACS Symposium Series,2015

    • Author(s)
      Seiichi Tada, Takanori Uzawa, and Yoshihiro Ito
    • Publisher
      アメリカ化学会
    • Related Report
      2014 Annual Research Report
  • [Book] “Photoreactive polymers for microarray chips”, in “Photo Cured Materials”2014

    • Author(s)
      Di Zhou, Ponnurengam Sivakumar Malliappan, Tae Il Son, and Yoshihiro Ito
    • Publisher
      RSC Publishing, UK
    • Related Report
      2013 Annual Research Report
  • [Book] “RNA as a nanomaterial” in “Encyclopedia of Polymeric Nanomaterials”2014

    • Author(s)
      Baiju Nair Govindan and Yoshihiro Ito
    • Publisher
      Springer
    • Related Report
      2013 Annual Research Report
  • [Book] “Cross-linking of biological components for stem cell culture” in “Functional Hydrogels as Biomaterials”2014

    • Author(s)
      Binata Joddar and Yoshihiro Ito
    • Publisher
      Springer
    • Related Report
      2013 Annual Research Report
  • [Book] 「第26章再生医療製品及び再生医療用基材における留意点」『医薬品・医療機器 承認取得のためのデータ・情報の取得とまとめ方(仮題)』2014

    • Author(s)
      伊藤嘉浩、吉田靖弘
    • Publisher
      技術情報協会
    • Related Report
      2013 Annual Research Report
  • [Book] 「進化分子工学のライブラリーの拡張―天然ソースから非天然ソースへ」、「進化分子工学の最前線」2013

    • Author(s)
      鵜澤尊規、多田誠一、伊藤嘉浩
    • Total Pages
      424
    • Publisher
      エヌ・ティー・エス
    • Related Report
      2013 Annual Research Report
  • [Book] 「骨の再生を促進する複合多孔質足場材料を開発」、「体内埋め込み医療とその理想的な性能・デザインの要件」2013

    • Author(s)
      川添直輝、陳国平、伊藤嘉浩
    • Total Pages
      440
    • Publisher
      技術情報協会
    • Related Report
      2013 Annual Research Report
  • [Book] Biomimetics: Advancing Nanobiomaterials and Tissue Engineering2013

    • Author(s)
      P. M. Sivakumar
    • Publisher
      John Wiley-Scrivener Publishing,
    • Related Report
      2012 Annual Research Report
  • [Book] Monographs in Supramolecular Chemistry No. 11, Polymeric and Self Assembled Hydrogels: From Fundamental Understanding to Applications2013

    • Author(s)
      X. J. Loh
    • Publisher
      The Royal Society of Chemistry
    • Related Report
      2012 Annual Research Report
  • [Book] ここまで来た人工骨・関節 -バイオマテリアルから再生医工学へ-2012

    • Author(s)
      伊藤嘉浩
    • Publisher
      米田出版
    • Related Report
      2012 Annual Research Report
  • [Book] Handbook of Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine2012

    • Author(s)
      T. Kitajima
    • Publisher
      Pan Stanford Publishing
    • Related Report
      2012 Annual Research Report
  • [Book] Wissenschaft und Klinische Praxis2012

    • Author(s)
      B. Van Meerbeek
    • Publisher
      Georg Thieme Verlag
    • Related Report
      2012 Annual Research Report
  • [Book] "Growth Factors and Protein Modified Surfaces and Interfaces," in "Comprehensive Biomaterials Vol.4, Surface Engineering"2011

    • Author(s)
      Yoshihiro Ito
    • Publisher
      Elsevier
    • Related Report
      2011 Annual Research Report
  • [Book] "Stabilized ribosome display for in vitro selection," in "Ribosome Display and Related Display Technologies : Methods and Protocols", "Methods in Molecular Biology"2011

    • Author(s)
      Shuta Hara, Mingzhe Liu, Wei Wang, Muye Xu, Zha Li, Yoshihiro Ito
    • Publisher
      Cambridge
    • Related Report
      2011 Annual Research Report
  • [Book] "Biomaterials for in vitro expansion of embryonic stem cells," in "Methodological Advances in the Culture, Manipulation and Utilization of Embryonic Stem Cells for Basic and Practical Applications"2011

    • Author(s)
      Makoto Sakuragi, Yoshihiro Ito
    • Publisher
      Intech.Janeza Trdine (Croatia)
    • Related Report
      2011 Annual Research Report
  • [Book] バイオマテリアルの基礎2010

    • Author(s)
      伊藤嘉浩
    • Publisher
      日本医学館
    • Related Report
      2010 Annual Research Report
  • [Patent(Industrial Property Rights)] アプタマーを用いた被検物の電気化学検出法2014

    • Inventor(s)
      伊藤嘉浩、多田誠一
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-204677
    • Filing Date
      2014-10-03
    • Related Report
      2014 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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