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Predictors of autism including low birth weight and social cognitive impairment: a longitudinal epidemiological study

Research Project

Project/Area Number 22249045
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Psychiatric science
Research InstitutionHamamatsu University School of Medicine

Principal Investigator

TAKEI Noriyoshi  浜松医科大学, 子どものこころの発達研究センター, 教授 (80206937)

Co-Investigator(Kenkyū-buntansha) SUZUKI Katsuaki  浜松医科大学, 子どものこころの発達研究センター, 准教授 (00285040)
TSUCHIYA Kenji  浜松医科大学, 子どものこころの発達研究センター, 准教授 (20362189)
MATSUMOTO Kaori  浜松医科大学, 子どものこころの発達研究センター, 助教 (20447808)
IWATA Keiko  浜松医科大学, 子どものこころの発達研究センター, 助教 (30415088)
SHIMMURA Chie  浜松医科大学, 子どものこころの発達研究センター, 特任研究員 (30529467)
中村 和彦  弘前大学, 医学(系)研究科(研究院), 教授 (80263911)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥33,280,000 (Direct Cost: ¥25,600,000、Indirect Cost: ¥7,680,000)
Fiscal Year 2012: ¥7,670,000 (Direct Cost: ¥5,900,000、Indirect Cost: ¥1,770,000)
Fiscal Year 2011: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
Fiscal Year 2010: ¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Keywords自閉症 / コホート研究 / 疫学 / 予測 / コホート / 低出生体重 / 子ども / 自閉症スペクトラム / 出生コホート / 縦断的疫学研究 / 社会認知 / 注視機能(eye gaze) / ASDの予測兆候
Research Abstract

No study has succeeded in establishing very early precursors for predicting autism spectrum disorder (ASD). To establish such precursors in behavioural as well as social context suggested in literature, we founded a birth cohort study in November, 2007: Hamamatsu Birth Cohort Study for Mothers and Children (HBC Study), in which more than 1,200 mother-and-infant dyads are involved and are currently followed-up. Among the participating children followed-up by the age of 32 months (N=549), 24 were diagnosed to have a consensus diagnosis of ASD. In the analyses using mixed modeling , we found that developmental milestones including sitting, response to joint attention, appropriate response to “Give it to me”, optical righting reflex, manipulative use of both hands, at the age of 10 months and14 months, are predictive of ASD diagnosis at the age of 32 months. Then, we combined these precursors to formulate a diagnostic algorithm, and resulted in sensitivity of 88% and specificity of 83%. We concluded that, using 5 developmental milestones, which are not confined in the well-known socialcognition domain, early predictive diagnosis of ASD at the age of around 1 year is possible.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (53 results)

All 2013 2012 2011 2010 Other

All Journal Article (36 results) (of which Peer Reviewed: 21 results) Presentation (7 results) (of which Invited: 1 results) Book (4 results) Remarks (3 results) Patent(Industrial Property Rights) (3 results) (of which Overseas: 1 results)

  • [Journal Article]2013

    • Author(s)
      Tsuchiya KJ, Matsumoto K, Yagi A, Inada N, Kuroda M, InokuchiE, Koyama T, Kamio Y, Tsujii M, Sakai S, Mohri I, Taniike M, Iwanaga R, Ogasahara K, Miyachi T, Nakajima S, Tani I, Ohnishi M, Inoue M, Nomura K, Hagiwara T, Uchiyama T, Ichikawa H, Kobayashi S, Miyamoto K, Nakamura K, Suzuki K, Mori N, Takei N.
    • Journal Title

      Journal of Autism and Developmental Disorders

      Volume: 43(3) Pages: 643-662

    • Related Report
      2012 Final Research Report
  • [Journal Article]2013

    • Author(s)
      Suzuki K, Sugihara G, Ouchi Y, Nakamura K, Futatsubashi M, Takebayashi K, Yoshihara Y, Omata K, Matsumoto K, Tsuchiya KJ, Iwata Y, Tsujii M, Sugiyama T, Mori N
    • Journal Title

      JAMA Psychiatry

      Volume: 70 Pages: 49-58

    • Related Report
      2012 Final Research Report
  • [Journal Article]2013

    • Author(s)
      Larsen JI, Andersen UA, Becker T, Bickel GG, Bork B, Cordes J, Frasch K, Jacobsen BA, Jensen SOW, Kilian R, Lauber C, Mogensen B, Nielsen JA, Rossler W, Tsuchiya KJ, Uwakwe R, Munk-Jorgensen P
    • Journal Title

      Australian and New Zealand Journal of Psychiatry

      Volume: 47(3) Pages: 250-258

    • Related Report
      2012 Final Research Report
  • [Journal Article] Reliability and validity of Autism Diagnostic Interview-Revised, Japanese Version2013

    • Author(s)
      Tsuchiya KJ
    • Journal Title

      Journal of Autism and Developmental Disorders

      Volume: 43 Issue: 3 Pages: 643-662

    • DOI

      10.1007/s10803-012-1606-9

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enzymes in the glutamate-glutamine cycle in the anterior cingulate cortex in postmortem brain of subjects with autism2013

    • Author(s)
      Shimmura C
    • Journal Title

      Molecular Autism

      Volume: 4 Issue: 1 Pages: 6-6

    • DOI

      10.1186/2040-2392-4-6

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Microglial activation in young adults with autism spectrum disorder2013

    • Author(s)
      Suzuki K
    • Journal Title

      JAMA Psychiatry

      Volume: 70 Issue: 1 Pages: 49-58

    • DOI

      10.1001/jamapsychiatry.2013.272

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article]2012

    • Author(s)
      Takahashi S, Tsuchiya KJ, Matsumoto K, Suzuki K, Mori N, Takei N
    • Journal Title

      Maternal & Child Health Journal

      Volume: 16 Pages: 947-955

    • Related Report
      2012 Final Research Report
  • [Journal Article]2012

    • Author(s)
      Tsuchiya KJ, Tsutsumi H, Matsumoto K, Takei N, Narumiya M, Honda M, Thanseem I, Anitha A, Suzuki K, Matsuzaki H, Iwata Y, Nakamura K, Mori N, for HBC Study Team
    • Journal Title

      PLoS One

      Volume: 7

    • Related Report
      2012 Final Research Report
  • [Journal Article] Seasonal Variations of Neuromotor Development By 14 Months of Age: Hamamatsu Birth Cohort for Mothers and Children (HBC Study)2012

    • Author(s)
      Tsutsumi H
    • Journal Title

      PLoS One

      Volume: 7 Issue: 12 Pages: e52057-e52057

    • DOI

      10.1371/journal.pone.0052057

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Brain region-specific altered expression and association of mitochondria-related genes in autism2012

    • Author(s)
      Anitha A
    • Journal Title

      Molecular Autism

      Volume: 3 Issue: 1 Pages: 12-12

    • DOI

      10.1186/2040-2392-3-12

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Psychosocial determinants of mistimed and unwanted pregnancy: the Hamamatsu Birth Cohort (HBC) Study2012

    • Author(s)
      Takahashi
    • Journal Title

      Maternal & Child Health Journal

      Volume: 16 Issue: 5 Pages: 947-955

    • DOI

      10.1007/s10995-011-0881-y

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Australian and New Zealand2011

    • Author(s)
      Iwata Y, Suzuki K, Takei N, Toulopoulou T, Tsuchiya KJ, Matsumoto K, Takagai S, Oshiro M, Nakamura K, Mori N
    • Journal Title

      Journal of Psychiatry

      Volume: 45 Pages: 148-52

    • Related Report
      2012 Final Research Report
  • [Journal Article] Archives of General Psychiatry2011

    • Author(s)
      Suzuki K, Sugihara G, Ouchi Y, Nakamura K, Tsujii M, Futatsubashi M, Iwata Y, Tsuchiya KJ, Matsumoto K, Takebayashi K, Wakuda T, Yoshihara Y, Suda S, KikuchiM, Takei N, Sugiyama T, Irie T, Mori N
    • Volume
      68
    • Pages
      306-13
    • Related Report
      2012 Final Research Report
  • [Journal Article]2011

    • Author(s)
      Suzuki K, Matsuzaki H, Iwata K, Kameno Y, Shimmura C, Kawai S, Yoshihara Y, Wakuda T, Takebayashi K, Takagai S, Matsumoto K, Tsuchiya KJ, Iwata Y, Nakamura K, Tsujii M, Sugiyama T, Mori N
    • Journal Title

      PLoS One

      Volume: 6

    • Related Report
      2012 Final Research Report
  • [Journal Article]2011

    • Author(s)
      SudaS, Iwata K, Shimmura C, Kameno Y, Anitha A, Thanseem I, Nakamura K, Matsuzaki H, Tsuchiya KJ, Sugihara G, Iwata Y, Suzuki K, Koizumi K, Higashida H, Takei N, Mori N
    • Journal Title

      Molecular Autism

      Volume: 2 Pages: 14-14

    • Related Report
      2012 Final Research Report
  • [Journal Article]2011

    • Author(s)
      Matsumoto K, Tsuchiya KJ, Itoh H, Kanayama N, Suda S, Matsuzaki H, Iwata Y, Suzuki K, Nakamura K, Mori N, Takei N, HBC Study Team
    • Journal Title

      Journal of Affective Disorders

      Volume: 133 Pages: 607-10

    • Related Report
      2012 Final Research Report
  • [Journal Article]2011

    • Author(s)
      Mori T, Tsuchiya KJ, Matsumoto K, Suzuki K, Mori N, Takei N, HBC Study Team
    • Journal Title

      Journal of Affective Disorders

      Volume: 135 Pages: 341-46

    • Related Report
      2012 Final Research Report
  • [Journal Article]2011

    • Author(s)
      Shimmura C, Suda S, Tsuchiya KJ, Hashimoto K, Ohno K, Matsuzaki H, Iwata K, Matsumoto K, Wakuda T, Kameno Y, Suzuki K, Tsujii M, Nakamura K, Takei N, Mori N
    • Journal Title

      PLoS One

      Volume: 6

    • Related Report
      2012 Final Research Report
  • [Journal Article]2011

    • Author(s)
      Iwata K, Matsuzaki H, Miyachi T, Shimmura C, Suda S, Tsuchiya KJ, Matsumoto K,Suzuki K, Iwata Y, Nakamura K, Tsujii M, Sugiyama T, Sato K, Mori N
    • Journal Title

      Molecular Autism

      Volume: 2 Pages: 16-16

    • Related Report
      2012 Final Research Report
  • [Journal Article] Muscarinic Receptor Occupancy and Cognitive Impairment : A PET Study with [(11)C](+)3-MPB and Scopolamine in Conscious Monkeys2011

    • Author(s)
      Yamamoto S, Nishiyama S, Kawamata M, Ohba H, Wakuda T, Takei N, Tsukada H, Domino EF
    • Journal Title

      Neuropsychopharmacology

      Volume: 36(7) Pages: 1455-65

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Age-specific 3-month cumulative incidence of postpartum depression : the Hamamatsu Birth Cohort (HBC) Study2011

    • Author(s)
      Matsumoto K, Tsuchiya KJ, Itoh H, Kanayama N, Suda S, Matsuzaki H, Iwata Y, Suzuki K, Nakamura K, Mori N, Takei N
    • Journal Title

      J Affect Disord

      Volume: 33(3) Pages: 607-10

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Psychosocial risk factors for postpartum depression and their relation to timing of onset : the Hamamatsu Birth Cohort (HBC)Study2011

    • Author(s)
      Mori T, Tsuchiya KJ, Matsumoto K, Suzuki K, Mori N, Takei N; HBC Study Team
    • Journal Title

      J Affect Disord

      Volume: 135(1-3) Pages: 341-6

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Decreased expression of axon-guidance receptors in the anterior cingulate cortex in autism2011

    • Author(s)
      Suda S, Iwata K, Shimmura C, Kameno Y, Anitha A, Thanseem I, Nakamura K, Matsuzaki H, Tsuchiya KJ, Sugihara G, Iwata Y, Suzuki K, Koizumi K, Higashida H, Takei N, Mori N
    • Journal Title

      Mol Autism

      Volume: 2(1) Pages: 14-14

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Psychosocial Determinants of Mistimed and Unwanted Pregnancy : The Hamamatsu Birth Cohort (HBC) Study2011

    • Author(s)
      Takahashi S, Tsuchiya KJ, Matsumoto K, Suzuki K, Mori N, Takei N; The HBC Study Team
    • Journal Title

      Matern Child Health J.

      Volume: 16 Pages: 947-955

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Alteration of plasma glutamate and glutamine levels in children with high-functioning autism2011

    • Author(s)
      Shimmura C, Suda S, Tsuchiya KJ, Hashimoto K, Ohno K, Matsuzaki H, Iwata K, Matsumoto K, Wakuda T, Kameno Y, Suzuki K, Tsujii M, Nakamura K, Takei N, Mori N
    • Journal Title

      PLoS One.

      Volume: 6(10)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Searching for very early precursors of autism spectrum disorders : the Hamamatsu Birth Cohort for Mothers and Children (HBC).2011

    • Author(s)
      Tsuchiya KJ, Matsumoto K, Suda S, Miyachi T, Itoh H, Kanayama N, Hirano K, Ohzeki T, Takei N, the HBC Study Team
    • Journal Title

      J Dev Origins Health Dis

      Volume: (In press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Jiko-shisen-kyofu (fear of one's own glance), but not taijin-kyofusho (fear of interpersonal relations), is an east Asian culture-related specific syndrome.2011

    • Author(s)
      Iwata Y, Suzuki K, Takei N, Toulopoulou T, Tsuchiya KJ, Matsumoto K, Takagai S, Oshiro M, Nakamura K, Mori N
    • Journal Title

      Aust N Z J Psychiatry

      Volume: 45(2) Pages: 148-152

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Replication study of Japanese cohorts supports the role of STX1A in autism susceptibility.2011

    • Author(s)
      Nakamura K, Iwata Y, Anitha A, Miyachi T, Toyota T, Yamada S, Tsujii M, Tsuchiya KJ, Iwayama Y, Yamada K, Hattori E, Matsuzaki H, Matsumoto K, Suzuki K, Suda S, Takebayashi K, Takei N, Ichikawa H, Sugiyama T, Yoshikawa T, Mori N.
    • Journal Title

      Prog Neuropsychopharmacol Biol Psychiatry

      Volume: 35(2) Pages: 454-458

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reduced acetylcholinesterase activity in the fusiform gyrus in adults with autism spectrum disorders.2011

    • Author(s)
      Suzuki K, Sugihara G, Ouchi Y, Nakamura K, Tsujii M, Futatsubashi M, Iwata Y, Tsuchiya KJ, Matsumoto K, Takebayashi K, Wakuda T, Yoshihara Y, Suda S, Kikuchi M, Takei N, Sugiyama T, Irie T, Mori N.
    • Journal Title

      Arch Gen Psychiatry

      Volume: 68(3) Pages: 306-313

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article]2010

    • Author(s)
      Tsuchiya KJ, Matsumoto K, Suda S, Miyachi T, Itoh H, KanayamaN, Hirano K, Ohzeki T, Takei N, HBC Study Team
    • Journal Title

      Journal of Developmental Origins of Health and Disease

      Volume: 1 Pages: 158-73

    • Related Report
      2012 Final Research Report
  • [Journal Article] Decreased serum levels of adiponectin in subjects with autism.2010

    • Author(s)
      Fujita-Shimizu A, Suzuki K, Nakamura K, Miyachi T, Matsuzaki H, Kajizuka M, Shinmura C, Iwata Y, Suda S, Tsuchiya KJ, Matsumoto K, Sugihara G, Iwata K, Yamamoto S, Tsujii M, Sugiyama T, Takei N, Mori N.
    • Journal Title

      Prog Neuropsychopharmacol Biol Psychiatry.

      Volume: 34(3) Pages: 455-458

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Metabolite alterations in the hippocampus of high-functioning adult subjects with autism.2010

    • Author(s)
      Suzuki K, Nishimura K, Sugihara G, Nakamura K, Tsuchiya KJ, Matsumoto K, Takebayashi K, Isoda H, Sakahara H, Sugiyama T, Tsujii M, Takei N, Mori N.
    • Journal Title

      Int J Neuropsychopharmacol.

      Volume: 13(4) Pages: 529-534

    • NAID

      120005305395

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Two genetic variants of CD38 in subjects with autism spectrum disorder and controls.2010

    • Author(s)
      Munesue T, Yokoyama S, Nakamura K, Anitha A, Yamada K, Hayashi K, Asaka T, Liu HX, Jin D, Koizumi K, Islam MS, Huang JJ, Ma WJ, Kim UH, Kim SJ, Park K, Kim D, Kikuchi M, Ono Y, Nakatani H, Suda S, Miyachi T, Hirai H, Salmina A, Pichugina YA, Soumarokov AA, Takei N, Mori N, Tsujii M, Sugiyama T, Yagi K, Yamagishi M, Sasaki T, Yamasue H, Kato N, Hashimoto R, Taniike M, Hayashi Y, Hamada J, Suzuki S, Ooi A, Noda M, Kamiyama Y, Kido MA, Lopatina O, Hashii M, Amina S, Malavasi F, Huang EJ, Zhang J, Shimizu N, Yoshikawa T, Matsushima A, Minabe Y, Higashida H.
    • Journal Title

      Neurosci Res

      Volume: 67(2) Pages: 181-191

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reduced expression of apolipoprotein E receptor type 2 in peripheral blood lymphocytes from patients with major depressive disorder.2010

    • Author(s)
      Suzuki K, Iwata Y, Matsuzaki H, Anitha A, Suda S, Iwata K, Shinmura C, Kameno Y, Tsuchiya KJ, Nakamura K, Takei N, Mori N.
    • Journal Title

      Prog Neuropsychopharmacol Biol Psychiatry

      Volume: 34(6) Pages: 1007-1010

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Further evidence for the role of MET in autism susceptibility.2010

    • Author(s)
      Thanseem I, Nakamura K, Miyachi T, Toyota T, Yamada S, Tsujii M, Tsuchiya KJ, Anitha A, Iwayama Y, Yamada K, Hattori E, Matsuzaki H, Matsumoto K, Iwata Y, Suzuki K, Suda S, Kawai M, Sugihara G, Takebayashi K, Takei N, Ichikawa H, Sugiyama T, Yoshikawa T, Mori N.
    • Journal Title

      Neurosci Res

      Volume: 68(2) Pages: 137-141

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article]

    • Author(s)
      Frasch K, Larsen JI, Cordes J, Jacobsen B, Wallenstein Jensen SO, Lauber C,Nielsen JA, Tsuchiya KJ, Uwakwe R, Munk-Jorgensen P, Kilian R, Becker T
    • Journal Title

      International Journal of Social Psychiatry

    • Related Report
      2012 Final Research Report
  • [Presentation] Measuring early courses of autism: a challenge of Hamamatsu Birth Cohort Study (HBC Study)2012

    • Author(s)
      Tsuchiya KJ
    • Organizer
      The 24th Annual Conference, International Society for Environment Epidemiology
    • Place of Presentation
      Columbia, SC
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Alteration of the expression balance of hnRNP C1 and C2 changes the expression of myelination-and schizophrenia-related genes in the human neuroblastima cell line2012

    • Author(s)
      Iwata K., Matsuzaki H., Takei N., Mori N.
    • Organizer
      3^<rd> Schizophrenia Intremational Research Society Conference
    • Place of Presentation
      Florence, Italy
    • Related Report
      2011 Annual Research Report
  • [Presentation] Alteration of several schizophrenia candidate genes expression in medial prefrontal cortex in perinatal apsyxia rodent model2012

    • Author(s)
      Wakuda T., Iwata K., Suzuki K., Takei N., Mori N.
    • Organizer
      3^<rd> Schizophrenia Intremational Research Society Conference
    • Place of Presentation
      Florence, Italy
    • Related Report
      2011 Annual Research Report
  • [Presentation] The pathobiology of autism : evidence from peripheral blood, postmortem, and neuroimaging studies2011

    • Author(s)
      Takei N
    • Organizer
      The Second Asia Maudsley Forum
    • Place of Presentation
      Hong Kong, China
    • Related Report
      2011 Annual Research Report
  • [Presentation] Longitudinal birth cohort study provides useful information on the relationships between various risk factors and subsequent developmental disturbances in children : based on the Hamamatsu Birth Cohort (HBC) Study2011

    • Author(s)
      Takei N
    • Organizer
      The Second Asia Maudsley Forum
    • Place of Presentation
      Hong Kong, China
    • Related Report
      2011 Annual Research Report
  • [Presentation] Postpartum depression and prepregnancy BMI: The Hamamatsu Birth Cohort (HBC) Study[conference proceeding]2010

    • Author(s)
      Mori T, Tsuchiya KJ, Matsumoto K, Muraki H, Takahashi S, Takabayashi R, Suzuki Y, Sato R, Narumiya M, Takei N, HBC Study Team
    • Organizer
      Longitudinal and Life Course Studies 1 (suppl 3): 372
    • Related Report
      2012 Final Research Report
  • [Presentation] Alteration of ALK1 and Neureglin-1 gene expression in frontal cortex and dentate gyrus may be ascoated with schizophrenia : perinatal asphyxia model in rat.2010

    • Author(s)
      Wakuda T., Suda, S., Iwata K., Suzuki K., Mori N., Takei N.
    • Organizer
      2^<nd> Schizophrenia Intrernational Research Society Conference.
    • Place of Presentation
      Florence, Italy
    • Related Report
      2010 Annual Research Report
  • [Book] Recent epidemiological studies of psychiatric disorders in Japan. In : Textbook in Psychiatric Epidemiology2011

    • Author(s)
      Kawai M., Tsuchiya J.K., Takei N.
    • Publisher
      Wiley-Blackwell, UK
    • Related Report
      2011 Annual Research Report
  • [Book] Disturbed growth in early life and later neurocognitive development related especially to psychiatric disorders. In : Handbook of Behavior, Diet and Nutrition. Eds Victor R Preedy, Ronald Ross Watson, and Colin Martin2011

    • Author(s)
      Suda S., Takei N.
    • Publisher
      Springer, London
    • Related Report
      2011 Annual Research Report
  • [Book] Textbook in Psychiatric Epidemiology

    • Author(s)
      Kawai M., Tsuchiya J.K., Takei N.(分担)[Eds P Jones, M Tsuang]
    • Publisher
      Wiley, London(In press)
    • Related Report
      2010 Annual Research Report
  • [Book] International Handbook of Behavior, Diet and Nutrition.

    • Author(s)
      Suda S., Takei N.(分担)[Eds Eds Victor R Preedy, Colin Martin, Ronald Ross Watson]
    • Publisher
      Springer, London(In press)
    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.rccmd.org/

    • Related Report
      2012 Final Research Report
  • [Remarks] 子どものこころの発達研究センター

    • URL

      http://rccmd.org/

    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://rccmd.org/modules/staff/index.php?content_id=3

    • Related Report
      2011 Annual Research Report
  • [Patent(Industrial Property Rights)] 自閉症診断支援方法およびシステム並びに自閉症診断支援装置2013

    • Inventor(s)
      森則夫、鈴木勝昭、土屋賢治、新村千江、桜井敬久、徳谷恵樹
    • Industrial Property Rights Holder
      森則夫、鈴木勝昭、土屋賢治、新村千江、桜井敬久、徳谷恵樹
    • Filing Date
      2013-03-13
    • Related Report
      2012 Final Research Report
    • Overseas
  • [Patent(Industrial Property Rights)] 自閉症診断支援方法およびシステム並びに自閉症診断支援装置2012

    • Inventor(s)
      森則夫、鈴木勝昭、土屋賢治、新村千江、桜井敬久、徳谷恵樹
    • Industrial Property Rights Holder
      森則夫、鈴木勝昭、土屋賢治、新村千江、桜井敬久、徳谷恵樹
    • Industrial Property Number
      2012-063237
    • Filing Date
      2012-03-21
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] 自閉症診断支援方法およびシステム並びに自閉症診断支援装置2012

    • Inventor(s)
      森則夫、鈴木勝昭、土屋賢治、新村千江、桜井敬久、徳谷恵樹
    • Industrial Property Rights Holder
      森則夫、鈴木勝昭、土屋賢治、新村千江、桜井敬久、徳谷恵樹
    • Industrial Property Number
      2013-030686
    • Filing Date
      2012-02-20
    • Related Report
      2012 Final Research Report

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Published: 2010-11-30   Modified: 2019-07-29  

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