| Budget Amount *help |
¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000)
Fiscal Year 2012: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2010: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
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| Research Abstract |
Prostaglandin E1(PGE1)Liple is the medication of prostaglandin E1. This drug is a drug delivery system which is in the form of micelles. In the current experiments, a high speed mixing device was devised to entrap gas within its structure. Analysis measurement resulted in significant difference in size before and after treatment at least in the range of 3-10 μm. It was strongly suggested that this new air trapped micelles could act as a contrast agent for ultrasound imaging and for delivery of various drugs, including prostaglandin E1.
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