| Budget Amount *help |
¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Fiscal Year 2012: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2011: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2010: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
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| Research Abstract |
In this study, an acute and chronic toxicities of growth and mature of nonyl phenol and related compounds on Americamysis bahia have been investigated. As results, these compounds showed adverse effects of growth and reproductive functions on the experimental organism. And also, reproductive effects were observed in addition to the growth effects. Nonyl phenols positively indicated adverse effect on reproductive function. Using DNA micro array, gene expression profiling of after exposed to noyl phenols mixture, 32 alternating genes expression exposed at 1ug/L, 27 genes at 3 ug/L, 43 genes at 10 ug/L, and 72 genes at 30 ug/L were detected. The possible participation of these alternating genes expression related to molting and reproduction on Americamysis bahia are suggested.
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