|Budget Amount *help
¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Fiscal Year 2013: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2012: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2011: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2010: ¥8,320,000 (Direct Cost: ¥6,400,000、Indirect Cost: ¥1,920,000)
In this study, we have designed phenylboronic acid azoprobes possessing various alkyl chain lengths (B-Azo-Cn (n = 6, 8, and 10)) and introduced it into a CyD cavity to form a gel for the selective adsorption of monosaccharides based on the template effect. The hydrophobic azoprobe, B-Azo-C10, was stably incorporated inside the gamma-CyD cavity and exhibited the highest adsorption selectivity for galactose. On the other hand the gamma-CyD gel with the glucose template exhibited glucose-selective adsorption. Based on the repositioning of the binding sites for target sugar recognition by repeating sugar adsorption, novel self-learning ability of CyD gel was successfully realized.