| Project/Area Number |
22350076
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Functional materials/Devices
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| Research Institution | Hokkaido University |
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Principal Investigator |
IJIRO Kuniharu 北海道大学, 電子科学研究所, 教授 (90221762)
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| Co-Investigator(Renkei-kenkyūsha) |
SANO Kenichi 理化学研究所, 分子情報生命科学特別研究ユニット, 副ユニットリーダー (80321769)
NIIKURA Kenichi 北海道大学, 電子科学研究所, 准教授 (40360896)
MATSUO Yasutaka 北海道大学, 電子科学研究所, 助教 (90374652)
SHIMAMOTO Naonobu 北海道大学, 電子科学研究所, 特任准教授 (50386629)
MITOMO Hideyuki 北海道大学, 電子科学研究所, 助教 (50564952)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥19,370,000 (Direct Cost: ¥14,900,000、Indirect Cost: ¥4,470,000)
Fiscal Year 2012: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2011: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥11,700,000 (Direct Cost: ¥9,000,000、Indirect Cost: ¥2,700,000)
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| Keywords | DNA / 自己組織化 / ナノ粒子 / 単電子トランジスタ / 量子ドット |
|---|
| Research Abstract |
DNA-based nanoparticle assembly is powerful tool for fabrication of nanostructures such as nano-patterning, whereas it is required to prepare nanoparticles in which a discrete and known number of single-stranded oligonucleotides are attached by thiol. We attempted to polymerize single primer-template DNA bound to Au nanoparticles by DNA polymerase, Klenow Fragment exo- (KF-), depending on reaction time. The AFM observation and gel electrophoresis suggest that KF- extended the short primer template bound to Au nanoparticle.
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