Effect on distribution and chemical speciation of Cd of chemical forms of Cd in diet.

Research Project

Project/Area Number	22380073
Research Category	Grant-in-Aid for Scientific Research (B)
Allocation Type	Single-year Grants
Section	一般
Research Field	Food science
Research Institution	The University of Tokyo
Principal Investigator	YOSHIMURA Etsuro 東京大学, 大学院・農学生命科学研究科, 教授 (10130303)
Co-Investigator(Kenkyū-buntansha)	SHINOHARA Atsuko 清泉女子大, 付置研究所, 教授 (90157850) MATSUKAWA Takehisa 順天堂大学, 医学部, 助教 (60453586) MATSUNAGA Toshiro 農業食品産業技術研究機構, 中央農研センター, チーム長 (20355647) FUKAMI Motohiro 宇都宮大学, 農学部, 教授 (50114624)
Project Period (FY)	2010 – 2012
Project Status	Completed (Fiscal Year 2012)
Budget Amount *help	¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000) Fiscal Year 2012: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000) Fiscal Year 2011: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000) Fiscal Year 2010: ¥8,320,000 (Direct Cost: ¥6,400,000、Indirect Cost: ¥1,920,000)
Keywords	食品安全性 / カドミウム / Cd / コメ / マウス / 体内動態 / 肝臓 / 腎
Research Abstract	Rice plants were grown in soil culture that contained Cd and 1.7 kg of rice grainswere obtained. In the grains Cd was found to be at a concentration of 3.9 ppm.HPLC-ICP/MS analysis was undertaken for the grain and revealed that 4 peaks wereresponsible for the chemical forms of Cd. From the feeding experiment against mouse,no difference in levels of Cd accumulation was found. However, a much greateraccumulation was seen when Cd-containing rice grains were fed.