Development of the effective and concise procedure to determine the concentrations of biogenic polyamines.
| Project/Area Number |
22390003
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | Kyoto Prefectural University |
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Principal Investigator |
TSUBAKI Kazunori 京都府立大学, 大学院・生命環境科学研究科, 教授 (50303897)
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| Co-Investigator(Kenkyū-buntansha) |
KURAMOCHI Kouji 京都府立大学, 大学院・生命環境科学研究科, 准教授 (90408708)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2012: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2010: ¥13,520,000 (Direct Cost: ¥10,400,000、Indirect Cost: ¥3,120,000)
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| Keywords | スペルミジン / スペルミン / 呈色応答 / ホスト-ゲスト / 分子認識 / 可視化 / ポリアミン / 超分子化学 / 蛍光色素 / 迅速定量 / マルチカラー |
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| Research Abstract |
We developed the third generation host molecule 2, which is changed the mother skeleton from the phenolphthalein to the phenol sulfonephthalein (Figure 2), with an extraordinary improvement in sensitivity and finally, achieved the detection of concentration of spermidine in E. coli. using host molecule 2 as a comparative level of HPLC method.
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Report
(4 results)
Research Products
(29 results)
