|Budget Amount *help
¥17,680,000 (Direct Cost: ¥13,600,000、Indirect Cost: ¥4,080,000)
Fiscal Year 2012: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2011: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2010: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
To identify the susceptibility genes for Behcet’ s disease, we conducted a genome-wide association study in a Japanese population and replication studies in Turkish and Korean populations. We identified two new susceptibility loci, IL23R-IL12RB2 and IL10, for Behcet’ s disease. In addition, we identified further new loci for the disease by re-assessing the GWAS data.