| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Research Abstract |
Presbycusis is a sensorineural hearing loss associated with age and appropriate mouse model for this disorder is required to clarify the mechanisms. Human nonsyndromic hereditary deafness (HDFN) and presbycusis possibly share the mechanism, which suggests that ENU-induced mouse mutants of deafness that are thought to be good models of HDFN may provide a cue to solve the mechanism. In this study, we have identified novel deafness genes for that we multilaterally approach to investigate its functions.
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