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Development of bio-imaging technology using cell surface-like monolayer membrane

Research Project

Project/Area Number 22500417
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Biomedical engineering/Biological material science
Research InstitutionKansai University

Principal Investigator

FURUIKE Tetsuya  関西大学, 化学生命工学部, 准教授 (10360942)

Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywordsシクロデキストリン / 両親媒性化合物 / 単分子膜 / 糖鎖クラスター効果 / バイオイメージング / 自己集積化 / 糖鎖 / 糖鎖クラスター / 両親媒性 / センシング
Research Abstract

As a part of the development of glycoclustered device, we focused on cyclodextrin (CD) having the rigid and symmetrical structure. The synthetic method for the sugar-binding type of CD amphiphiles (GlycoCD amphiphiles), having bioactive sugars and long-chain fatty acids onto the CD, is established. The formation behavior of monolayers which is a two-dimensional molecular assembly is discussed by the use of the GlycoCD amphiphiles.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (58 results)

All 2013 2012 2011 2010 Other

All Journal Article (14 results) (of which Peer Reviewed: 13 results) Presentation (41 results) Book (2 results) Remarks (1 results)

  • [Journal Article] Methods of N-acetylated chitosan scaffolds and its in-vitro biodegradation by lysozyme2012

    • Author(s)
      T. Han, N. Nwe, T. Furuike, S. Tokura, H. Tamura
    • Journal Title

      J. Biomedical Science and Engineering

      Volume: 5 Issue: 01 Pages: 15-23

    • DOI

      10.4236/jbise.2012.51003

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Methods of N-acetylated chitosan scaffolds and its in-vitro biodegradation by lysozyme.2012

    • Author(s)
      T. Han, N. Nwe, T. Furuike, S. Tokura, and H. Tamura
    • Journal Title

      Journal of Biomedical Science and Engineering

      Volume: 5 Pages: 15-23

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] キチン・キトサンベースの機能材料2012

    • Author(s)
      田村 裕, 古池 哲也
    • Journal Title

      機能材料

      Volume: 32 Pages: 15-21

    • Related Report
      2012 Annual Research Report
  • [Journal Article] Chitin scaffolds in tissue engineering2011

    • Author(s)
      R. Jayakumar, K.P. Krishna, S. Srinivasan, S.V. Nair, T. Furuike, H. Tamura
    • Journal Title

      Int. J. Mol. Sci.

      Volume: 12 Pages: 1876-1887

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of chitosan-coated fibers as a scaffold for three-dimensional cultures of rabbit fibroblasts for ligament tissue engineering2011

    • Author(s)
      J.Sarukawa, T.Furuike
    • Journal Title

      J.Biomater.Sci.

      Volume: 22 Issue: 4-6 Pages: 717-732

    • DOI

      10.1163/092050610x491067

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Laboratory scale production of ^<13>C labeled chitosan by fungi Absidia coerulea and Gongronella butleri grown in solid substrate and submerged fermentation2011

    • Author(s)
      N.Nwe, T.Furuike
    • Journal Title

      Carbohydr.Polymers

      Volume: 84 Issue: 2 Pages: 743-750

    • DOI

      10.1016/j.carbpol.2010.06.023

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Biomedical applications of chitin hydrogel membranes and scaffolds2011

    • Author(s)
      H.Tamura, T.Furuike
    • Journal Title

      Carbohydr.Polymers

      Volume: 84 Issue: 2 Pages: 820-824

    • DOI

      10.1016/j.carbpol.2010.06.001

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chitin scaffolds in tissue engineering2011

    • Author(s)
      R.Jayakumar, T.Furuike
    • Journal Title

      Int.J.Mol.Sci.

      Volume: 12 Issue: 3 Pages: 1876-1887

    • DOI

      10.3390/ijms12031876

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preparation and characterization of chitosan-gelatin/ nano hydroxyapatite composite scaffolds for tissue engineering applications2010

    • Author(s)
      M. Peter, N. Ganesh, N. Selvamurugan, S.V. Nair, T. Furuike, H. Tamura, R. Jayakumar
    • Journal Title

      Carbohydr. Polymers

      Volume: 80 Issue: 3 Pages: 687-694

    • DOI

      10.1016/j.carbpol.2009.11.050

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nanocomposite scaffolds of bioactive glass ceramic nanoparticles disseminated chitosan matrix for tissue engineering applications.2010

    • Author(s)
      M.Peter, N.S.Binulal, S.Soumya, S.V.Nair, T.Furuike, H.Tamura, R.Jayakumar
    • Journal Title

      Carbohydrate Polymers

      Volume: 79 Pages: 284-298

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of gamma radiation on dilute aqueous solutions and thin films of N-succinyl chitosan.2010

    • Author(s)
      C.Vanichvattanadecha, P.Supaphol, N.Nagasawa, M.Tamada, S.Tokura, T.Furuike, H.Tamura, R.Rujiravanit
    • Journal Title

      Polymer Degradation and Stability

      Volume: 95 Pages: 234-244

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Selection of a biopolymer based on attachment, morphology and proliferation of fibroblast NIH/3T3 cells for the development of a biodegradable tissue regeneration template : Alginate, bacterial cellulose and gelatin.2010

    • Author(s)
      N.Nwe, T.Furuike, H.Tamura
    • Journal Title

      Process Biochemistry

      Volume: 45 Pages: 457-466

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preparation and characterization of chitosan-gelatin/nano hydroxyapatite composite scaffolds for tissue engineering applications.2010

    • Author(s)
      M.Peter, N.Ganesh, N.Selvamurugan, S.V.Nair, T.Furuike, H.Tamura, R.Jayakumar
    • Journal Title

      Carbohydrate Polymers

      Volume: 80 Pages: 687-694

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preparation of poly (lactic acid)/chitosan nanoparticles for anti HIV drug delivery applications.2010

    • Author(s)
      Ashish Dev, N.S.Binulal, A.Anitha, S.V.Nair, T.Furuike, H.Tamura, R.Jayakumar
    • Journal Title

      Carbohydrate Polymers

      Volume: 80 Pages: 833-838

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] イオン液体を用いた糖鎖合成法2013

    • Author(s)
      平井智也、田村裕、古池哲也
    • Organizer
      第17回先端科学技術シンポジウム
    • Place of Presentation
      大阪
    • Related Report
      2012 Final Research Report
  • [Presentation] イオン液体を用いた糖鎖合成法2013

    • Author(s)
      平井 智也,田村 裕, 古池 哲也
    • Organizer
      第17回先端科学技術シンポジウム
    • Place of Presentation
      関西大学(大阪府)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Development of Carbohydrate Synthesis Using Ionic Liquids2012

    • Author(s)
      S. Okamura, T. Hirai, T. Furuike, H. Tamura
    • Organizer
      The 3rd Research Symposium on Petrochemical and Materials Technology and The 18th PPC Symposium on Petroleum, Petrochemicals, and Polymers
    • Place of Presentation
      Bangkok, Thailand
    • Year and Date
      2012-04-24
    • Related Report
      2012 Final Research Report
  • [Presentation] 化学-酵素合成法を用いた人工複合糖質化合物の合成研究2012

    • Author(s)
      古池哲也
    • Organizer
      第16回先端科学技術シンポジウム
    • Place of Presentation
      関西大学(大阪府)
    • Year and Date
      2012-01-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] シクロデキストリンを用いた両親媒性化合物の合成と機能2012

    • Author(s)
      岡村俊佑,田村裕, 古池哲也
    • Organizer
      第31回日本糖質学会年会
    • Place of Presentation
      鹿児島
    • Related Report
      2012 Final Research Report
  • [Presentation] マイクロ波を用いたオリゴ糖の化学修飾2012

    • Author(s)
      平井智也、田村裕、古池哲也
    • Organizer
      第31回日本糖質学会年会
    • Place of Presentation
      鹿児島
    • Related Report
      2012 Final Research Report
  • [Presentation] Chemo- enzymatic synthesis of glycoclustered cyclodextrins (GlycoCDs)2012

    • Author(s)
      T. Furuike, H. Tamura
    • Organizer
      The 7th International Symposium in Science and Technology: Bridging Research for Advancement of Knowledge and Technology
    • Place of Presentation
      Penang, Malaysia
    • Related Report
      2012 Final Research Report
  • [Presentation] イオン液体を用いた糖鎖合成法2012

    • Author(s)
      平井智也、田村裕、古池哲也
    • Organizer
      第26回キチン・キトサンシンポジウム
    • Place of Presentation
      札幌
    • Related Report
      2012 Final Research Report
  • [Presentation] 化学-酵素合成法を用いた人工複合糖質化合物の合成研究2012

    • Author(s)
      古池哲也
    • Organizer
      第16回先端科学技術シンポジウム
    • Place of Presentation
      大阪
    • Related Report
      2012 Final Research Report
  • [Presentation] イオン液体を用いた糖鎖合成法2012

    • Author(s)
      平井 智也,田村 裕, 古池 哲也
    • Organizer
      第26回キチン・キトサンシンポジウム
    • Place of Presentation
      北海道大学(北海道)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Chemo-enzymatic synthesis of glycoclustered cyclodextrins (GlycoCDs).2012

    • Author(s)
      T. Furuike and H. Tamura
    • Organizer
      The 7th International Symposium in Science and Technology: Bridging Research for Advancement of Knowledge and Technology
    • Place of Presentation
      Penang, Malaysia
    • Related Report
      2012 Annual Research Report
  • [Presentation] シクロデキストリンを用いた両親媒性化合物の合成と機能2012

    • Author(s)
      岡村 俊佑,田村 裕, 古池 哲也
    • Organizer
      第31回日本糖質学会年会
    • Place of Presentation
      鹿児島市民文化ホール(鹿児島)
    • Related Report
      2012 Annual Research Report
  • [Presentation] マイクロ波を用いたオリゴ糖の化学修飾2012

    • Author(s)
      平井 智也,田村 裕, 古池 哲也
    • Organizer
      第31回日本糖質学会年会
    • Place of Presentation
      鹿児島市民文化ホール(鹿児島)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Development of hemostatic material using chitinous sponge and its mechanism of action2011

    • Author(s)
      H.Tamura T.Furuike
    • Organizer
      The 2^<nd> Research Symposium on Petroleum and Petrochemicals, and Advanced Materials and The 17^<th> PPC Symposium on Petroleum and Petrochemicals, and Polymers
    • Place of Presentation
      Bangkok, Thailand
    • Year and Date
      2011-04-26
    • Related Report
      2011 Annual Research Report
  • [Presentation] Preparation of chitosan-coated PLA film2011

    • Author(s)
      D.Komoto, T.Furuike
    • Organizer
      The 2^<nd> Research Symposium on Petroleum and Petrochemicals, and Advanced Materials and The 17^<th> PPC Symposium on Petroleum and Petrochemicals, and Polymers
    • Place of Presentation
      Bangkok, Thailand
    • Year and Date
      2011-04-26
    • Related Report
      2011 Annual Research Report
  • [Presentation] Preparation of phosphoryl chitin and its application2011

    • Author(s)
      K.Ogata, T.Furuike
    • Organizer
      The 2^<nd> Research Symposium on Petroleum and Petrochemicals, and Advanced Materials and The 17^<th> PPC Symposium on Petroleum and Petrochemicals, and Polymers
    • Place of Presentation
      Bangkok, Thailand
    • Year and Date
      2011-04-26
    • Related Report
      2011 Annual Research Report
  • [Presentation] Preparation and characterization of β-chitin/Poly (2-hydroxyethyl methacrylate)2011

    • Author(s)
      Y.Ohnishi, T.Furuike
    • Organizer
      The 2^<nd> Research Symposium on Petroleum and Petrochemicals, and Advanced Materials and The 17^<th> PPC Symposium on Petroleum and Petrochemicals, and Polymers
    • Place of Presentation
      Bangkok, Thailand
    • Year and Date
      2011-04-26
    • Related Report
      2011 Annual Research Report
  • [Presentation] Preparation and characterization of chitosan- coated PLA fiber and braided rope2011

    • Author(s)
      T. Furuike, D. Komoto, H. Nagahama, S. Maki, H. Seo, H. Tamura
    • Organizer
      The 9th Asia-Pacific Chitin and Chitosan Symposium
    • Place of Presentation
      Nha Trang, Vietnam
    • Related Report
      2012 Final Research Report
  • [Presentation] Modification and glycosylation of carbohydrates in ionic liquids2011

    • Author(s)
      T. Hirai, H. Tamura, T. Furuike
    • Organizer
      6th International Symposium in Science and Technology at Kansai University 2011, Collaboration between Asian countries in materials, chemistry, life science, information technology, civil engineering and ecological interface design
    • Place of Presentation
      Osaka, Japan
    • Related Report
      2012 Final Research Report
  • [Presentation] 細菌表層由来オリゴ糖の合成2011

    • Author(s)
      松村勲、田村裕、古池哲也
    • Organizer
      第25回キチン・キトサンシンポジウム
    • Place of Presentation
      奈良
    • Related Report
      2012 Final Research Report
  • [Presentation] 固相合成法を用いたオリゴ糖の合成2011

    • Author(s)
      箕輪英之、田村裕、古池哲也
    • Organizer
      第25回キチン・キトサンシンポジウム
    • Place of Presentation
      奈良
    • Related Report
      2012 Final Research Report
  • [Presentation] イオン液体を用いた糖鎖合成法の開発2011

    • Author(s)
      平井智也、田村裕、古池哲也
    • Organizer
      第30回日本糖質学会年会
    • Place of Presentation
      長岡
    • Related Report
      2012 Final Research Report
  • [Presentation] Preparation and characterization of chitosan-coated PLA fiber and braided rope2011

    • Author(s)
      T.Furuike
    • Organizer
      The 9^<th> Asia-Pacific Chitin and Chitosan Symposium
    • Place of Presentation
      Nha Trang, Vietnam
    • Related Report
      2011 Annual Research Report
  • [Presentation] Modification and glycosylation of carbohydrates in ionic liquids2011

    • Author(s)
      T.Hirai, T.Furuike
    • Organizer
      6^<th> International Symposium in Science and Technology at Kansai University 2011, Collaboration between Asian countries in materials, chemistry, life science, information technology, civil engineering and ecological interface design
    • Place of Presentation
      Osaka, Japan
    • Related Report
      2011 Annual Research Report
  • [Presentation] Preparation of chitin/bacterial cellulose composite2011

    • Author(s)
      Y.Nishie, T.Furuike
    • Organizer
      6^<th> International Symposium in Science and Technology at Kansai University 2011, Collaboration between Asian countries in materials, chemistry, life science, information technology, civil engineering and ecological interface design
    • Place of Presentation
      Osaka, Japan
    • Related Report
      2011 Annual Research Report
  • [Presentation] Preparation of chitosan-coated PLA fiber2011

    • Author(s)
      D.Komoto, T.Furuike
    • Organizer
      6^<th> International Symposium in Science and Technology at Kansai University 2011, Collaboration between Asian countries in materials, chemistry, life science, information technology, civil engineering and ecological interface design
    • Place of Presentation
      Osaka, Japan
    • Related Report
      2011 Annual Research Report
  • [Presentation] 細菌表層含有デオキシ糖の合成2011

    • Author(s)
      松村勲, 古池哲也
    • Organizer
      第30回日本糖質学会年会
    • Place of Presentation
      長岡リリックホール(新潟県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] イオン液体を用いた糖鎖合成法の開発2011

    • Author(s)
      平井智也, 古池哲也
    • Organizer
      第30回日本糖質学会年会
    • Place of Presentation
      長岡リリックホール(新潟県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] キトサン表面修飾PLA繊維の調製2011

    • Author(s)
      河本大毅, 古池哲也
    • Organizer
      第40回医用高分子シンポジウム
    • Place of Presentation
      関西大学(大阪府)
    • Related Report
      2011 Annual Research Report
  • [Presentation] イオン液体を用いた糖鎖合成法の開発2011

    • Author(s)
      平井智也, 古池哲也
    • Organizer
      第25回キチン・キトサンシンポジウム
    • Place of Presentation
      奈良新公会堂(奈良県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 細菌表層由来オリゴ糖の合成2011

    • Author(s)
      松村勲, 古池哲也
    • Organizer
      第25回キチン・キトサンシンポジウム
    • Place of Presentation
      奈良新公会堂(奈良県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 固相合成法を用いたオリゴ糖の合成2011

    • Author(s)
      箕輪英之, 古池哲也
    • Organizer
      第25回キチン・キトサンシンポジウム
    • Place of Presentation
      奈良新公会堂(奈良県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] キチン・キトサン繊維の紡糸2010

    • Author(s)
      古池哲也
    • Organizer
      繊維学会東海支部講演会
    • Place of Presentation
      名古屋工業大学
    • Year and Date
      2010-11-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] キチンコンポジット繊維の紡糸2010

    • Author(s)
      古池哲也, 高田卓, 瀬尾寛, 田村裕
    • Organizer
      第24回キチン・キトサンシンポジウム
    • Place of Presentation
      東京大学
    • Year and Date
      2010-07-13
    • Related Report
      2010 Annual Research Report
  • [Presentation] キチン・キトサン関連オリゴ糖の合成2010

    • Author(s)
      森川嵩士, 古池哲也, 田村裕
    • Organizer
      第24回キチン・キトサンシンポジウム
    • Place of Presentation
      東京大学
    • Year and Date
      2010-07-13
    • Related Report
      2010 Annual Research Report
  • [Presentation] 人工硬膜を指向したPLAフィルムの表面改質2010

    • Author(s)
      河本大毅, 牧真司, 古池哲也, 田村裕
    • Organizer
      第24回キチン・キトサンシンポジウム
    • Place of Presentation
      東京大学
    • Year and Date
      2010-07-13
    • Related Report
      2010 Annual Research Report
  • [Presentation] Advantages and disadvantages of production of non-labeled chitosan and ^<13>C-labeled chitosan from fungal source compared with production of chitosans from crustacean, insect and mushroom source.2010

    • Author(s)
      N.Nwe, T.Furuike, H.Tamura
    • Organizer
      第24回キチン・キトサンシンポジウム
    • Place of Presentation
      東京大学
    • Year and Date
      2010-07-13
    • Related Report
      2010 Annual Research Report
  • [Presentation] Production of low molecular weight chitosan and chitoologosaccharides : Gamma-ray irradiation, acid hydrolysis and enzymatic hydrolysis method.2010

    • Author(s)
      N.Nwe, T.Furuike, H.Tamura
    • Organizer
      第24回キチン・キトサンシンポジウム
    • Place of Presentation
      東京大学
    • Year and Date
      2010-07-13
    • Related Report
      2010 Annual Research Report
  • [Presentation] Chemical and enzymatic synthesis of cyclodextrin- scaffolded glycoclusters (GlycoCDs)2010

    • Author(s)
      T. Furuike, H. Tamura
    • Organizer
      Pacifichem2010
    • Place of Presentation
      Honolulu, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] キチン・キトサン関連オリゴ糖の合成2010

    • Author(s)
      森川嵩士、田村裕、古池哲也
    • Organizer
      第24回キチン・キトサンシンポジウム
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] Development of Carbohydrate Synthesis Using Ionic Liquids.

    • Author(s)
      S. Okamura, T. Hirai, T. Furuike and H. Tamura
    • Organizer
      The 3rd Research Symposium on Petrochemical and Materials Technology and The 18th PPC Symposium on Petroleum, Petrochemicals, and Polymers
    • Place of Presentation
      Bangkok, Thailand
    • Related Report
      2012 Annual Research Report
  • [Book] Chitosan conjugated DNA nanoparticles delivery systems for gene therapy. Chitin, Chitosan, Oligosaccharides and Their Derivatives : Biological Activities and Applications2010

    • Author(s)
      R.Jayakumar, K.P.Chennazhi, S.V.Nair, T.Furuike, H.Tamura
    • Total Pages
      8
    • Publisher
      Crc Pr 1 Llc.
    • Related Report
      2010 Annual Research Report
  • [Book] Chitin and chitosan from terrestrial organisms." Chitin, Chitosan, Oligosaccharides and Their Derivatives : Biological Activities and Applications2010

    • Author(s)
      N.Nwe, T.Furuike, H.Tamura
    • Total Pages
      13
    • Publisher
      Crc Pr 1 Llc.
    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.chemmater.kansai-u.ac.jp/biofunc/

    • Related Report
      2012 Final Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

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