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Age-related augmentation of blood pressure response to exercise

Research Project

Project/Area Number 22500496
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionNational Institute of Advanced Industrial Science and Technology

Principal Investigator

KOMINE Hidehiko  独立行政法人産業技術総合研究所, ヒューマンライフテクノロジー研究部門, 主任研究員 (10392614)

Co-Investigator(Kenkyū-buntansha) SUGAWARA Jun  独立行政法人 産業技術総合研究所, ヒューマンライフテクノロジー研究部門, 主任研究員 (00357261)
YOKOI Takashi  独立行政法人 産業技術総合研究所, ヒューマンライフテクノロジー研究部門, 副研究部門長 (80192805)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywords理学療法学 / 動脈血圧反射 / 心拍数 / 血圧 / 運動
Research Abstract

The purpose of this study was to clarify the underling mechanism(s) that are responsible for the age-related augmentation of blood pressure response during exercise. To clarify the mechanism(s), we focused on the arterial baroreflex. We thus developed a d

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (50 results)

All 2013 2012 2011 2010 Other

All Journal Article (19 results) (of which Peer Reviewed: 18 results) Presentation (25 results) (of which Invited: 1 results) Book (6 results)

  • [Journal Article] Non-invasive assessment of arterial stiffness using oscillometric blood pressure measurement2012

    • Author(s)
      Komine H, Asai Y, Yokoi T, Yoshizawa M
    • Journal Title

      Biomedical engineering online

      Volume: (掲載確定)(印刷中) Issue: 1 Pages: 11-6

    • DOI

      10.1186/1475-925x-11-6

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of Chronic Exercise Training on the Blood Pressure Response to Orthostatic Stimulation2012

    • Author(s)
      Sugawara J, Komine H, Miyazawa T, Imai T, Fisher JP, Ogoh S
    • Journal Title

      J Appl Physiol

      Volume: 112(11):1891-6

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Modulation of radial blood flow during Braille character discrimination task2012

    • Author(s)
      Murata J, Matsukawa K, Komine H, Tsuchimochi H
    • Journal Title

      Acta Physiol Hung

      Volume: 99(1):25-32

    • NAID

      120006985411

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of exercise training on the baroreflex control of arterial blood pressure2012

    • Author(s)
      Komine H
    • Journal Title

      J Physiol Sci

      Volume: 62 (Suppl 1)

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Modulation of radial blood flow during Braille character discrimination task.2012

    • Author(s)
      Murata J, Matsukawa K, Komine H, Tsuchimochi H
    • Journal Title

      Acta Physiol Hung

      Volume: 99 Issue: 1 Pages: 25-32

    • DOI

      10.1556/aphysiol.99.2012.1.3

    • NAID

      120006985411

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of exercise training on the Daroreflex control of arterial blood pressure2012

    • Author(s)
      Komine H
    • Journal Title

      The Journal of Physiological Sciences

      Volume: 62(Supple 1)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High circulating levels of oxidized LDL in strength-trained athletes2011

    • Author(s)
      Choi Y, Maeda S, Yoshizawa M, Tanabe K, Miyaki A, Tanabe Y, Komine H, Hirayama A, Shiraki H, Ajisaka R
    • Journal Title

      Journal of Exercise Nutrition & Biochemistry

      Volume: 15(2): 105-110

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The effects of regular endurance exercise on IL-6 and the sympathetic nervous system2011

    • Author(s)
      Komine H, Yoshizawa M, Maeda S, Shimojo N, Takai Y, Akazawa N, and Yokoi T
    • Journal Title

      FASEB J

      Volume: 25

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Circulating endothelial progenitor cells in strength-trained men2011

    • Author(s)
      Yoshizawa M, Maeda S, Choi Youngju, Shimojo N, and Komine H
    • Journal Title

      FASEB J

      Volume: 25

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The effects of regular endurance exercise on IL-6 and the sympathetic nervous system2011

    • Author(s)
      Komine H, Yoshizawa M, Maeda S, Shimojo N, Takai Y, Akazawa N, and Yokoi T
    • Journal Title

      J Physiol Sci

      Volume: 61 (Suppl 1)

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The effects of regular endurance exercise on IL-6 and the sympathetic nervous system2011

    • Author(s)
      Komine H, Yoshizawa M.Maeda S, Shimojo N, Takai Y, Akazawa N, Yokoi T
    • Journal Title

      FASEB Journal

      Volume: 25

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Circulating endothelial progenitor cells in strength-trained men2011

    • Author(s)
      Mutsuko Yosnizawa, Maeda S, Choi Y, Shimojo N, Komine H
    • Journal Title

      FASEB Journal

      Volume: 25

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 不活動による心身の変化2011

    • Author(s)
      小峰秀彦
    • Journal Title

      Posture

      Volume: 37 Pages: 32-38

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 血管の硬さをはかる2011

    • Author(s)
      小峰秀彦
    • Journal Title

      日本機械学会誌

      Volume: 114 Pages: 856-857

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Racial defferences in relation between carotid and radial augmentation index2010

    • Author(s)
      Sugawara J, Komine H, Yoshizawa M, Tarumi T, Maeda S, Tanaka H
    • Journal Title

      Artery Res

      Volume: 4(1): 15-15

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of regular endurance exercise on brachial blood flow response to mental stress2010

    • Author(s)
      Komine H, Takai Y, Akazawa N, Maeda S, Yoshizawa M, Sugawara J, and Yokoi T
    • Journal Title

      FASEB J

      Volume: 24

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Sort- and longterm effects of exercise on the arterial baroreflexes2010

    • Author(s)
      Komine Hand Matsukawa K
    • Journal Title

      J Physiol Sci

      Volume: 60 (Suppl 1)

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Racial Differences in Relation Between Carotid and Radial Augmentation Index2010

    • Author(s)
      Jun Sugawara, et al
    • Journal Title

      Artery Res

      Volume: 4(1) Pages: 15-18

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of regular endurance exercise on brachial blood flow response to mental stress2010

    • Author(s)
      Hidehiko Komine, et al
    • Journal Title

      The Journal of Physiological Sciences

      Volume: 60(Supple)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] A method of evaluating the aortic baroreflex in human2013

    • Author(s)
      Komine H、 YoshizawaM、Miyazawa T
    • Organizer
      第90回日本生理学会
    • Place of Presentation
      タワーホール船堀(東京)
    • Year and Date
      2013-03-29
    • Related Report
      2012 Final Research Report
  • [Presentation] 動脈血圧反射受容器の刺激を利用した血圧調節機能評価とその応用2013

    • Author(s)
      小峰 秀彦
    • Organizer
      日本機械学会 第25回バイオエンジニアリング講演会
    • Place of Presentation
      産業技術総合研究所(茨城)
    • Year and Date
      2013-01-11
    • Related Report
      2012 Final Research Report
  • [Presentation] 動脈血圧反射受容器の刺激を利用した血圧調節機能評価とその応用2013

    • Author(s)
      小峰 秀彦
    • Organizer
      第25回バイオエンジニアリング講演会
    • Place of Presentation
      茨城
    • Related Report
      2012 Annual Research Report
  • [Presentation] ヒトにおける大動脈弓圧受容器反射の評価手法2013

    • Author(s)
      小峰秀彦,宮澤太機,吉澤睦子
    • Organizer
      第90回日本生理学会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
  • [Presentation] 上腕で測る血管指標2012

    • Author(s)
      小峰 秀彦
    • Organizer
      第37回日本運動療法学会
    • Place of Presentation
      鷹産業プラザ(東京)
    • Year and Date
      2012-06-24
    • Related Report
      2012 Final Research Report
  • [Presentation] Effects of exercise training on the baroreflex control of arterial blood pressure2012

    • Author(s)
      Komine H
    • Organizer
      第89回日本生理学会
    • Place of Presentation
      松本文化会館(長野)
    • Year and Date
      2012-03-30
    • Related Report
      2012 Final Research Report
  • [Presentation] Effects of exercise training on the baroreflex control of arterial blood pressure2012

    • Author(s)
      Komine H
    • Organizer
      The 87th Annual Meeting of the Physiological Society of Japan
    • Place of Presentation
      長野県松本文化会館(長野県)
    • Year and Date
      2012-03-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] 上腕で測る血管指標2012

    • Author(s)
      小峰 秀彦
    • Organizer
      第37回日本運動療法学会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 全身運動時の頭部皮膚血流量の変化は近赤外線分光法による脳活動の評価に影響する2012

    • Author(s)
      宮澤太機、小峰 秀彦、堀内雅弘、菅原順、小河繁彦
    • Organizer
      日本体力医学会
    • Place of Presentation
      岐阜
    • Related Report
      2012 Annual Research Report
  • [Presentation] 動脈硬化を診る意義を再考する2011

    • Author(s)
      小峰秀彦
    • Organizer
      第11回日本AS学会
    • Place of Presentation
      ルークホール(東京)
    • Year and Date
      2011-10-01
    • Related Report
      2012 Final Research Report
  • [Presentation] 動脈硬化を診る意義を再考する2011

    • Author(s)
      小峰秀彦
    • Organizer
      第11回日本AS学会
    • Place of Presentation
      ルークホール(東京)(招待講演)
    • Year and Date
      2011-10-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] 3 週間の下肢免荷が足関節底屈運動時の膝窩動脈血流応答に与える影響2011

    • Author(s)
      峰 秀彦、吉澤睦子、赤澤暢彦、横井 孝志
    • Organizer
      第46回日本理学療法学術大会
    • Place of Presentation
      シーガイアコンベンションセンター(宮崎)
    • Year and Date
      2011-05-29
    • Related Report
      2012 Final Research Report
  • [Presentation] 3週間の下肢免荷が足関節底屈運動時の膝窩動脈血流応答に与える影響2011

    • Author(s)
      小峰秀彦, 吉澤睦子, 赤澤暢彦, 横井孝志
    • Organizer
      第46回日本理学療法学術大会
    • Place of Presentation
      シーガイアコンベンションセンター(宮崎県)
    • Year and Date
      2011-05-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] The effects of regular endurance exercise on IL-6 and the sympathetic nervous system2011

    • Author(s)
      Komine H, Yoshizawa M, Maeda S, Shimojo N, Takai Y, Akazawa N, and Yokoi T
    • Organizer
      Experimental Biology
    • Place of Presentation
      Washigton Convention Center (USA)
    • Year and Date
      2011-04-12
    • Related Report
      2012 Final Research Report
  • [Presentation] Circulating endothelial progenitor cells in strength-trained men2011

    • Author(s)
      Yoshizawa M, Maeda S, Choi Youngju, Shimojo N, and Komine H
    • Organizer
      Experimental Biology
    • Place of Presentation
      Washigton Convention Center (USA)
    • Year and Date
      2011-04-12
    • Related Report
      2012 Final Research Report
  • [Presentation] The effects of regular endurance exercise on IL-6 and the sympathetic nervous syste2011

    • Author(s)
      Komine H, Yoshizawa M, Maeda S, Shimojo N, Takai Y, Akazawa N, Yokoi T
    • Organizer
      Experimental Biology 2011
    • Place of Presentation
      Washington Convention Center, Washington DC, USA
    • Year and Date
      2011-04-11
    • Related Report
      2011 Annual Research Report
  • [Presentation] circulating endothelial progenitor cells in strength-trained men2011

    • Author(s)
      Mutsuko Yoshizawa, Maeda S, Choi Y, Shimojo N, Komine H
    • Organizer
      Experimental Biology 2011
    • Place of Presentation
      Washington Convention Center, Washington DC, USA
    • Year and Date
      2011-04-11
    • Related Report
      2011 Annual Research Report
  • [Presentation] The effects of regular endurance exercise on IL-6 and the autonomic nervous system2011

    • Author(s)
      Komine H, Yoshizawa M, Maeda S, Shimojo N, Takai Y, Akazawa N, and Yokoi T
    • Organizer
      第88回日本生理学会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2011-03-29
    • Related Report
      2012 Final Research Report
  • [Presentation] 血圧計を応用した動脈硬化測定装置の開発2010

    • Author(s)
      小峰秀彦
    • Organizer
      第10回日本AS学会
    • Place of Presentation
      ルークホール(東京)
    • Year and Date
      2010-10-23
    • Related Report
      2012 Final Research Report
  • [Presentation] 血圧計を応用した動脈硬化測定装置の開発2010

    • Author(s)
      小峰秀彦
    • Organizer
      日本AS学会
    • Place of Presentation
      東京
    • Year and Date
      2010-10-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] Exercise training and the arterial baroreflex2010

    • Author(s)
      Hidehiko Komine
    • Organizer
      第6回Body And Mind Integrated Sports Sciences
    • Place of Presentation
      つくば
    • Year and Date
      2010-09-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] Short- and longterm effects of exercise on the arterial baroreflexes2010

    • Author(s)
      Komine H, Matsukawa K
    • Organizer
      第87回日本生理学会
    • Place of Presentation
      盛岡市民文化ホール(岩手)
    • Year and Date
      2010-05-20
    • Related Report
      2012 Final Research Report
  • [Presentation] Short- and longterm effects of exercise on the arterial baroreflexes2010

    • Author(s)
      Hidehiko Komine, et al.
    • Organizer
      The 87^<th> Annual Meeting of the Physiological Society of Japan
    • Place of Presentation
      盛岡
    • Year and Date
      2010-05-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] Effects of regular endurance exercise on brachial blood flow response to mental stress2010

    • Author(s)
      Hidehiko Komine, et al.
    • Organizer
      Experimental Biology
    • Place of Presentation
      Anaheim
    • Year and Date
      2010-04-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] Effects of regular endurance exercise on brachial blood flow response to mental stress2010

    • Author(s)
      Komine H, Takai Y, Akazawa N, Maeda S, Yoshizawa M, Sugawara J, and Yokoi T
    • Organizer
      Experimental Biology
    • Place of Presentation
      Anaheim Convention Center (USA)
    • Year and Date
      2010-04-26
    • Related Report
      2012 Final Research Report
  • [Book] 運動時の心臓自律神経活動調節, In: 身体運動と呼吸・循環機能2012

    • Author(s)
      小峰秀彦,松川寛二
    • Publisher
      真興交易(株)医書出版部
    • Related Report
      2012 Final Research Report
  • [Book] 身体運動と呼吸・循環機能2012

    • Author(s)
      小峰秀彦,松川寛二
    • Total Pages
      342
    • Publisher
      真興交易(株)医書出版
    • Related Report
      2012 Annual Research Report
  • [Book] 運動時の心臓自律神経活動調節,In:身体運動と呼吸循環2012

    • Author(s)
      小峰秀彦
    • Publisher
      真興出版(株)(印刷中)
    • Related Report
      2011 Annual Research Report
  • [Book] セントラルコマンドと循環調節. In:運動生理学のニューエビデンス2010

    • Author(s)
      小峰秀彦, 宮村実晴
    • Publisher
      真興交易(株)医書出版部
    • Related Report
      2012 Final Research Report
  • [Book] セントラルコマンドと循環調節In:運動生理学のニューエビデンス2010

    • Author(s)
      小峰秀彦, 他
    • Total Pages
      462
    • Publisher
      真興交易(株)医書出版
    • Related Report
      2010 Annual Research Report
  • [Book] 循環器

    • Author(s)
      小峰秀彦
    • Publisher
      人間工学ハンドブック(印刷中)
    • Related Report
      2012 Final Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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