Fabrication of Stable Nano-Structured Membranes for Formation of Artificial Cell Membranes

• Project/Area Number: 22510106
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Nanostructural science
• Research Institution: National Institute of Advanced Industrial Science and Technology
• Principal Investigator: SAWAGUCHI Takahiro 独立行政法人産業技術総合研究所, バイオメディカル研究部門, 主任研究員 (50357175)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 表面 / 界面ナノ構造 / 機能性超薄膜 / プローブ顕微鏡 / 自己組織化 / 構造・機能材料 / 表面・界面物性 / ナノ構造分子膜 / 人工細胞膜

Research Abstract

Newly synthesized phosphorylcholine derivatives were used to fabricate biomimetic and mono-molecular nano-structured membranes for stable introduction of biomolecules without loss of their functions. The nano-struntured membranes formed on an Au(111) sing

Research Products

• [Journal Article] In Situ Scanning Tunneling Microscopy Study of Interfacial Structures of Self-Assembled Monolayers of 3-(2-Pyridithio)Propionyl Hydradide on Au(111) (2013)
  • Author(s): 平 修、金子大作、横山憲二、澤口隆博
  • Journal Title: Molecular Imaging & Dynamics Volume: (in press) Issue: 02
  • DOI: 10.4172/2155-9937.s1-001
  • Peer Reviewed
• [Journal Article] Surface Modification of Silicon Oxide with Trialkoxysilanes toward Close-Packed Monolayer Formation (2013)
  • Author(s): Tanaka, Mutsuo; Sawaguchi, Takahiro; Kuwahara, Masashi; Niwa, Osamu.
  • Journal Title: Langmuir Volume: 未定
  • Peer Reviewed
• [Journal Article] Surface Modification of GC and HOPG with Diazonium, Amine, Azide, and Olefin Derivatives (2011)
  • Author(s): 田中睦生、 澤口隆博、佐藤 縁、吉岡恭子、丹羽 修
  • Journal Title: Langmuir Volume: vol. 27 Issue: 1 Pages: 170-178
  • DOI: 10.1021/la1035757
  • Peer Reviewed
• [Journal Article] Surface Modification of GC and HOPG with Diazonium, Amine, Azid, and Olefin Derivatives. (2011)
  • Author(s): 田中睦生、澤口隆博、佐藤縁、吉岡恭子、丹羽修
  • Journal Title: Langmuir Volume: Vol.27 Pages: 170-178
  • Peer Reviewed
• [Journal Article] Microstructure of Electrodeposited Nano-Crystalline Au-Ni Alloy Films. (2011)
  • Author(s): 井上貴裕、佐藤和男、横島時彦、澤口隆博、杉山敦、沖中裕、逢坂哲彌
  • Journal Title: ECS Transactions Volume: Vol.33 Pages: 27-34
  • Peer Reviewed
• [Journal Article] Surface Modification of Silicon Oxide with Trialkoxysilanes toward Close-Packed Monolayer Formation
  • Author(s): 田中睦生、 澤口隆博、桑原正史、丹羽 修
  • Journal Title: Langmuir Volume: (in press)
  • Peer Reviewed
• [Presentation] ナノ構造分子膜の構築と分子レベル構造・機能解析 (2013)
  • Author(s): 澤口隆博
  • Organizer: 電気化学会第80回大会(招待講演)
  • Place of Presentation: 東北大学(宮城県)
  • Year and Date: 2013-03-29
• [Presentation] カーボン(HOPG)電極上に化学結合したナノ構造分子膜の構造・機能評価 (2013)
  • Author(s): 澤口隆博、田中睦生
  • Organizer: 電気化学会第80回大会
  • Place of Presentation: 東北大学(宮城県)
  • Year and Date: 2013-03-29
• [Presentation] カーボン(HOPG)電極上に化学結合したナノ構造分子膜の構造・機能評価 (2013)
  • Author(s): 澤口隆博、田中睦生
  • Organizer: 電気化学会第８０回大会
  • Place of Presentation: 東北大学／仙台
• [Presentation] ナノ構造分子膜の構築と分子レベル構造・機能解析 (2013)
  • Author(s): 澤口隆博
  • Organizer: 電気化学会第８０回大会
  • Place of Presentation: 東北大学／仙台
  • Invited
• [Presentation] Interfacial Structure and Function of Nano-Structured Membranes of Newly Synthesized Phsphorylcholine Derivatives (2012)
  • Author(s): 澤口隆博 、田中睦生
  • Organizer: PACIFIC RIM MEETING 2012 on Electrochemical and Solid-State Science
  • Place of Presentation: Hilton Hotel(Hawaii/米国)
  • Year and Date: 2012-10-09
• [Presentation] Electrochemical Formation of Cu-Corronene Adlayer on Au(111) in Acidic Solution. (2012)
  • Author(s): Sawaguchi, Takahiro; Yoshimoto, Soichiro.
  • Organizer: PACIFIC RIM MEETING 2012 on Electrochemical and Solid-State Science
  • Place of Presentation: Honolulu/Hawaii
• [Presentation] Interfacial Structure and Function of Nano-Structured Membranes of Newly Synthesized Phosphorylcholine Derivatives. (2012)
  • Author(s): Sawaguchi, Takahiro; Tanaka, Mutsuo.
  • Organizer: PACIFIC RIM MEETING 2012 on Electrochemical and Solid-State Science
  • Place of Presentation: Honolulu/Hawaii
• [Presentation] Electrochemical Formation of Cu-Corronene Adlayer on Au(111) (2011)
  • Author(s): 澤口隆博、吉本惣一郎
  • Organizer: 62nd Annual Meeting of the International Society of Electrochemistry
  • Place of Presentation: 朱鷺メッセ/新潟市
  • Year and Date: 2011-09-15
• [Presentation] ホスホリルコリン新規ナノ構造分子膜の界面構造・機能評価 (2011)
  • Author(s): 澤口隆博、田中睦生
  • Organizer: 2011 電気化学秋季大会
  • Place of Presentation: 朱鷺メッセ(新潟県)
  • Year and Date: 2011-09-10
• [Presentation] ホスホリルコリン新規ナノ構造分子膜の界面構造・機能評価 (2011)
  • Author(s): 澤口隆博、田中睦生
  • Organizer: 2011電気化学秋季大会
  • Place of Presentation: 朱鷺メッセ/新潟市
  • Year and Date: 2011-09-10
• [Presentation] Atomic/Molecular Level Investigation of Electrified Interface-Electrochemical Scanning Tunneling Microscopy (EC-STM)- (2011)
  • Author(s): 澤口隆博
  • Organizer: 1st Korea-Japan R&D Collaboration Day
  • Place of Presentation: Busan/KOREA(招待講演)
  • Year and Date: 2011-05-31
• [Presentation] Nanostructure of Corronene-Cu Adlayer Formed by Electrochemical Deposition of Cu on Corronene Adsorbed Au(111) Electrode. (2010)
  • Author(s): 澤口隆博
  • Organizer: 2010 International Chemical Congress of Pacific Basin Societies
  • Place of Presentation: Sheraton Hotel (Honolulu/Hawaii)
  • Year and Date: 2010-12-15
• [Patent(Industrial Property Rights)] 表面修飾シリコン基板 (2010)
  • Inventor(s): 田中睦生、澤口隆博、佐藤 縁、吉岡恭子、丹羽 修
  • Industrial Property Rights Holder: 産業技術総合研究所
  • Industrial Property Number: 2010-189219
  • Filing Date: 2010-08-26
• [Patent(Industrial Property Rights)] 表面修飾シリコン基板 (2010)
  • Inventor(s): 田中睦生、澤口隆博、佐藤縁、吉岡恭子、丹羽修
  • Industrial Property Rights Holder: 産業技術総合研究所
  • Industrial Property Number: 2010-189219
  • Filing Date: 2010-08-26