Development of lower-interactive, stable, brighter near-infrared fluorescent dyes and their application to bio-imaging
| Project/Area Number |
22590051
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Physical pharmacy
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| Research Institution | Fukuoka University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | イメージング / 蛍光色素 / 糖化ローダミン / ラベル化 / 長波長 / 近赤外蛍光色素 / ローダミン色素 / シアニン色素 / シクロデキストリン包接 / 蛍光修飾 |
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| Research Abstract |
Fluorescence analyses play an important role in progress of biosciences, but the fluorescence dyes remain unchanged for long time. This study aimed to develop lower-interactive, stable, water-soluble, highly fluorescent dyes. The developed novel dyes “glycated rohdamines” show unique features “highly water-soluble and lower-interactivity with bio-molecules”. This study afford a typical methodology for developing new fluorescent dyes.
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Report
(4 results)
Research Products
(85 results)
