| Project/Area Number |
22590175
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General anatomy (including Histology/Embryology)
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| Research Institution | Kumamoto University |
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Principal Investigator |
YOSHINAGA Kazuya 熊本大学, 大学院・生命科学研究部, 教授 (50136719)
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| Co-Investigator(Kenkyū-buntansha) |
SUZUKI Kentaro 和歌山県立医科大学, 先端医学研究所, 講師 (20404345)
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| Research Collaborator |
TAJIRI Shota 熊本大学, 大学院・保健学教育部, 大学院生
FUKUI Tatsuya 熊本大学, 大学院・保健学教育部, 大学院生
MURAKAMI Kana 熊本大学, 大学院・保健学教育部, 大学院生
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 細胞・組織 / 発生・分化 / 生殖器 / 生殖細胞 / 糖鎖 |
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| Research Abstract |
To elucidate the molecular mechanism of morphogenesis anddifferentiation of reproductive organs, we examined the expression of the genes andmolecules on the reproductive tissues during fetal and postnatal development of mice. Theresults indicate that differences in lectin-binding patterns among regions or cell typesof the epididymal epithelium may be related to functional differentiation of theepididymis, and also indicate that differences in gene expressions of several growthfactors and transcription factors between male and female fetuses may be related tofunctional formation of the external genitalia.
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