| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Research Abstract |
Objectives:This research project was undertaken to elucidate underlying mechanisms for the establishment and maintenance of infection by analyzing expression and regulation of helminth proteins, especially mitochondrial proteins,responding to changing oxygen tension. Achievements:The current research showed: 1)Ascaris suum adult-specific cytochrome b5played the crucial roles in the parasitic adaptation.2)Paragonimus westermani possesses aerobic and anaerobic mitochondria in different tissues, adapting to fluctuating oxygen tension in microaerobic habitats.
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