| Project/Area Number |
22590576
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Akita University |
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Principal Investigator |
NARITA Takuma 秋田大学, 大学院・医学系研究科, 准教授 (70282168)
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| Co-Investigator(Kenkyū-buntansha) |
FUJITA Hiroki 秋田大学, 医学部, 講師 (30333933)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 疫学 / 微量アルブミン尿 / 慢性腎臓病 / 糖尿病腎症 / 心血管疾患 / 尿アルブミン / HPLC法 |
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| Research Abstract |
The objectives of this study are 1) to test the efficacy of measurement of urinary albumin excretion by the novel HPLC method for predicting future development of diabetic nephropathy in diabetic patients without nephropathy and cardiovascular diseases in general population. We have established the cohort of approximately 100 diabetic outpatients without nephropathy and of approximately 1300 subjects who participated in annual health examination at Kita-akita city. Measurement and evaluation of urinary albumin excretions by HPLC and conventional method at the baseline had already done and we have found that the discrepancy of the urinary albumin values between HPLC method and conventional one. Also, in the general population of Kita-akita city, we found that approximately one fifth of people have chronic kidney disease, that is the indicator of high risk of future development of renal failure and cardiovascular diseases. We will continue prospective observation of this cohort regarding the development of cardiovascular diseases.
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