| Project/Area Number |
22590578
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
|
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| Research Institution | University of Tsukuba |
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Principal Investigator |
OKUNO Junko 筑波大学, 医学医療系, 研究員 (50360342)
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| Co-Investigator(Kenkyū-buntansha) |
TOMURA Shigeo 浦和大学, 総合福祉学部, 教授 (60100955)
YANAGI Hisako 筑波大学, 医学医療系, 准教授 (10241811)
TANAKA Kiyoji 筑波大学, 体育系, 教授 (50163514)
OKURA Tomohiro 筑波大学, 体育系, 准教授 (60396611)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2012: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 介護予防 / 25(OH)D濃度 / 体力 / 腎機能 / ビタミンD補充 / 特定高齢者 / eGFR / 運動教室 / ビタミンD製剤 / 25(OH)D / 25(OH)D_3 / 1,25(OH)_2D_3 |
|---|
| Research Abstract |
The prevalence of eGFR < 60.0 ml/min/1.73m2was about 24.3%, and that of 25(OH)D < 75 nmol/L was 86.4%. Pre eGFR, pre 25(OH)D, and vitamin D supplementationwere significantly associated with improvement of mobility and muscle power. Our data suggest that assessment of renal function and maintaining appropriate vitamin D levels seem to be significant for independent living in the pre-frail elderly and higher 25(OH)D level might be needed for improvement of muscle strength than mobility; if possible, a 25(OH)D level greater than 67.5 nmol/L is preferable.
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