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The effects of smoking cessation on appetite regulation -ghrelin and GLP-1-.

Research Project

Project/Area Number 22590659
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field General internal medicine (including Psychosomatic medicine)
Research InstitutionOita University

Principal Investigator

ABE Koh  大分大学, 医学部医学科, 准教授 (80336297)

Co-Investigator(Kenkyū-buntansha) TAKESHIMA Fuminao  長崎大学, 医歯薬学総合研究科, 准教授 (70284693)
INOUE Keita  長崎大学, 医歯薬学総合研究科, 助教 (20515829)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords禁煙 / 摂食中枢関連ホルモン / グレリン / GLP-1 / ヘリコバクター・ピロリ菌 / H.pylori
Research Abstract

We tried to investigate the mechanism of body mass gain after smoking cessation, using the appetite related hormones and Helicobacter pylori. We examined 28 patients in smoking cessation outpatient. After smoking cessation, the appetite, body mass, waist size was significantly increased. The relation between weight gain and H. pylori, ghrelin were not significant. GLP-1 was also showed no significant relation to body mass gain, but decreasing tendency after smoking cessation. GLP-1 might played an important roll for the early weight gain after smoking cessation.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

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