The molecular pathogenesis of hepatocellular carcinoma
| Project/Area Number |
22590715
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Gastroenterology
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| Research Institution | Chiba University |
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Principal Investigator |
KANAI Fumihiko 千葉大学, 大学院・医学研究院, 講師 (70334399)
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| Co-Investigator(Kenkyū-buntansha) |
TADA Motohisa 千葉大学, 医学部附属病院, 助教 (00554239)
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| Project Period (FY) |
2010 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 肝臓学 / 肝細胞癌 / オリゴヌクレオチドアレイ / ヘッジホッグシグナル |
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| Research Abstract |
We analyzed the alteration of Hedgehog and Hippo signal in hepatocelluar carcinoma based on the results which was already detected by comprehensive analysis of genomic alteration using SNP array. We detected Hedgehog interacting protein, Suppresor of fused, and Sarvador homolog 1 was involved in the hepatocarcinogenesis and progression of hepatocellular carcinoma.
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Report
(4 results)
Research Products
(6 results)
