| Project/Area Number |
22590820
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Circulatory organs internal medicine
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| Research Institution | Asahikawa Medical College |
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Principal Investigator |
KAWABE Junichi 旭川医科大学, 医学部, 特任准教授 (10400087)
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| Co-Investigator(Kenkyū-buntansha) |
HIRA Yoshiki 旭川医科大学, 医学部, 講師 (70199024)
OKADA Motoi 旭川医科大学, 医学部, 講師 (80431427)
TAKEHARA Naofumi 旭川医科大学, 医学部, 特任講師 (90374793)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Keywords | 分子血管病態学 / 血管新生 / 血管成熟化 / 血管安定化 / 末梢神経再生 / 動脈硬化 / 神経再生 |
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| Research Abstract |
We showed that relationship between vascular maturation/stabilization of microvasculature within injured arterial walls and regeneration of peri-vascular peripheral nerve, and that nerve regenerative factors induced the renervation around the neovessels and subsequently vascular maturation/stabilization of microvessels.
We demonstrated for the first time that peripheral nerves fibers were already regenerated around the microvessels in patho-physiological condition to induce the vascular maturation.
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