| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Research Abstract |
We analyzed induction of TSLP in human primary keratinocytes. Staphylococcus aurous, which is known to colonize in skin of atopic dermatitis patients, bacterial flagellin, and atopic cytokine milieu, induced TSLP. We found that detection of the long form TSLP gene expression was a sensitive assay. The study identified some novel environmental and self-factors that contribute to the TSLP induction and regulation.
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