| Project/Area Number |
22591343
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NISHIE Akihiro 九州大学, 大学病院, 助教 (20457427)
FUJITA Nobuhiro 九州大学, 医学研究院, 助教 (30610612)
USHIJIMA Yasuhiro 九州大学, 医学研究院, 助教 (40432934)
TAKAYAMA Yukihisa 九州大学, 医学研究院, 助教 (60546563)
HONDA Hiroshi 九州大学, 医学研究院, 助教 (90145433)
NAKAYAMA Tomohiro 国立国際医療センター病院, 放射線診療部, 医師 (70419571)
TAJIMA Tsuyoshi 東京女子医科大学, 画像診断学核医学講座, 准教授 (50346798)
KAKIHARA Daisuke 九州大学, 医学研究院, 助教 (80529818)
ISHIGAMI Kousei 九州大学, 大学病院, 助教 (10403916)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 肝幹細胞 / 細胆管癌 / 肝細胞癌 / 胆管細胞癌 / CT / MRI / 線維化 / 脂肪化 / 肝腫瘤 / MRI(核磁気共鳴画像) / Gd-EOB-DTPA |
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| Research Abstract |
(1)Cholangiolocellular carcinoma has the dual imaging characteristics of hepatocellular carcinoma and cholangiocarcinoma. (2)Gadoxetic acid-enhanced MRI was found useful for differentiating intrahepatic cholangiocarcioma and poorly differentiated hepatocellular carcinoma, especially during the dynamic late phase.(3)The frequency of fatty change in pHCC, as well as in wHCC, is significantly higher than that of mHCC. One possible mechanism of it is intratumoral decreased arterial flow
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