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The development of the intraoperative determination system of the treatment effect of the hepatic arterial chemoembolization by using the high-definition fusion CT image

Research Project

Project/Area Number 22591371
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionTokyo Women's Medical University

Principal Investigator

TAJIMA Tsuyoshi  東京女子医科大学, 医学部, 准教授 (50346798)

Co-Investigator(Kenkyū-buntansha) KOHNO Mari  東京女子医科大学, 医学部, 助教 (30318050)
KIMURA Ken  東京女子医科大学, 医学部, その他 (70611284)
YAMAZAKI Hiroshi  東京女子医科大学, 医学部, その他 (90611286)
NISHIE Hiroshi  九州大学, 大学病院, 講師 (20457427)
ASAYAMA Yoshiki  九州大学, 大学病院, 講師 (40380414)
ISHIGAMI Kousei  九州大学, 大学病院, 助教 (10403916)
KAKIHARA Daisuke  九州大学, 大学病院, 助教 (80529818)
NAKAYAMA Tomohiro  九州大学, 大学病院, 医員 (70419571)
Co-Investigator(Renkei-kenkyūsha) NISHIE Akihiro  九州大学, 大学病院, 講師 (20457427)
ASAYAMA Yoshiki  九州大学, 大学病院, 講師 (40380414)
ISHIGAMI Kousei  九州大学, 大学病院, 助教 (10403916)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords動注化学塞栓療法 / 予後因子 / 融合画像 / CT / IVR / 動注療法化学塞栓療法
Research Abstract

We compared the values analyzed from the results of three-dimensional CT fusion images in patients with HCCs treated by CT-guided TACE withthe follow-up data from 2008 through 2010. As a result of medium-term follow-up, local recurrence rate was 60% and time to recurrence was 14-1008 days. By the comparison between recurrent group and non-recurrence group, a significant difference was found in the safety margin (Grade I vs. Grade II to IV, 6.6+-14.7mm vs. 17.5+-18.2mm: p=0.01) and local recurrence rate (56% vs. 96%: p

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (40 results)

All 2013 2012 2011 2010 Other

All Journal Article (15 results) (of which Peer Reviewed: 1 results) Presentation (24 results) (of which Invited: 3 results) Remarks (1 results)

  • [Journal Article] CT prediction of histological grade of hypervascular hepatocellular carcinoma: utility of the portal phase2012

    • Author(s)
      Nishie A, Yoshimitsu K, Okamoto D, Tajima T, Asayama Y, Ishigami K, Kakihara D, Nakayama T, Takayama Y, Shirabe K, Fujita N, Honda H.
    • Journal Title

      Jpn J Radiol

      Volume: [Epub ahead of print]

    • NAID

      210000178163

    • Related Report
      2012 Final Research Report
  • [Journal Article] MR prediction of liver fibrosis using a liver-specific contrast agent: Superparamagnetic iron oxide versus Gd-EOB-DTPA2012

    • Author(s)
      Nishie A, Asayama Y, Ishigami K, Tajima T, Kakihara D, Nakayama T, Takayama Y, Okamoto D, Taketomi A, Shirabe K, Fujita N, Obara M, Yoshimitsu K, Honda H.
    • Journal Title

      J Magn Reson Imaging

      Volume: 36(3) Pages: 664-71

    • Related Report
      2012 Final Research Report
  • [Journal Article] Radiological catheter placement for transcatheter arterial steroid injection therapy to treat severe acute hepatic failure: technical feasibility and efficacy2012

    • Author(s)
      Ushijima Y, Tajima T, Yoshimitsu K, Irie H, Nishie A, Hirakawa M, Ishigami K, Okamoto D, Kotoh K, Honda H
    • Journal Title

      Acta Radiol

      Volume: 53(2) Pages: 140-6

    • Related Report
      2012 Final Research Report
  • [Journal Article] 鼡径管でダンベル状を呈した悪性末梢神経鞘腫瘍の 1 例2012

    • Author(s)
      木村 健、田嶋 強、西原雄之介、河野真里、坂井修二、萩原洋子、加藤義治、橋本拓造、亀岡信悟、西川俊郎
    • Journal Title

      臨床放射線

      Volume: 57(7) Pages: 983-988

    • Related Report
      2012 Final Research Report
  • [Journal Article] 周術期管理に必要な画像診断のポイント:CT・MRI を中心に2012

    • Author(s)
      田嶋 強
    • Journal Title

      臨床麻酔

      Volume: 36(12) Pages: 1725-1732

    • Related Report
      2012 Final Research Report
  • [Journal Article] Diagnostic performance of apparent diffusion coefficient for predicting histological grade of hepatocellular carcinoma2011

    • Author(s)
      Nishie A, Tajima T, Asayama Y, Ishigami K, Kakihara D, Nakayama T, Takayama Y, Okamoto D, Fujita N, Taketomi A, Yoshimitsu K, Honda H.
    • Journal Title

      Eur J Radiol

      Volume: 80(2)

    • Related Report
      2012 Final Research Report
  • [Journal Article] Uptake of Gd-EOB-DTPA by hepatocellular carcinoma: radiologic-pathologic correlation with special reference to bile production2011

    • Author(s)
      Asayama Y, Tajima T, Nishie A, Ishigami K, Kakihara D, Nakayama T, Okamoto D, Fujita N, Aishima S, Shirabe K, Honda H.
    • Journal Title

      Eur J Radiol

      Volume: 80(3)

    • Related Report
      2012 Final Research Report
  • [Journal Article] Hepatocellular carcinoma with marginal superparamagnetic iron oxide uptake on T2*-weighted magnetic resonance imaging: histopathologic correlation2011

    • Author(s)
      Ishigami K, Tajima T, Fujita N, Nishie A, Asayama Y, Kakihara D, Nakayama T, Okamoto D, Taketomi A, Shirabe K, Honda H.
    • Journal Title

      Eur J Radiol

      Volume: 80(3)

    • Related Report
      2012 Final Research Report
  • [Journal Article] Clinical Challenge この画像から何が読めるか? 問題:肝腫瘤2011

    • Author(s)
      中山智博、田嶋 強、本田 浩
    • Journal Title

      肝胆膵画像

      Volume: 13(3) Pages: 232-233

    • Related Report
      2012 Final Research Report
  • [Journal Article] Clinical Challenge この画像から何が読めるか? 前号の問題と解答:肝腫瘤2011

    • Author(s)
      中山智博、田嶋 強、本田 浩
    • Journal Title

      肝胆膵画像

      Volume: 13(5) Pages: 566-569

    • Related Report
      2012 Final Research Report
  • [Journal Article] Safety margins of hepatocellular carcinoma demonstrated by 3-dimensional fused images of computed tomographic hepatic arteriography/unenhanced computed tomography: prognostic significance in patients who underwent transcatheter arterial chemoembolization2010

    • Author(s)
      Tajima T, Nishie A, Asayama Y, Ishigami K, Ushijima Y, Kakihara D, Honda H.
    • Journal Title

      Journal of Computer Assisted Tomography

      Volume: 34 Pages: 712-719

    • Related Report
      2012 Final Research Report
  • [Journal Article] 超音波検査の基礎的知識2010

    • Author(s)
      柿原大輔、 田嶋 強、本田 浩
    • Journal Title

      臨牀と研究

      Volume: 87 (5) Pages: 591-594

    • Related Report
      2012 Final Research Report
  • [Journal Article] 領域別に見る MDCT の診断・検査 up-to-date. 上腹部領域における 64 列 MDCT の有用性-肝臓を中心に2010

    • Author(s)
      西江昭弘、田嶋 強、藤田展宏、浅山良樹、 石神康生、 柿原大輔、 中山智博、高山幸久、本田浩.
    • Journal Title

      INNERVISION

      Volume: 25 Pages: 53-56

    • Related Report
      2012 Final Research Report
  • [Journal Article] 最新分類に基づく画像による悪性腫瘍の病期診断 2010 膵2010

    • Author(s)
      石神康生、田嶋 強、平川雅和、西江昭弘、 浅山良樹、 柿原大輔、 中山智博、岡本大佑、本田浩
    • Journal Title

      臨床画像

      Volume: 26 Pages: 98-109

    • Related Report
      2012 Final Research Report
  • [Journal Article] Safety margins of hepatocellular carcinoma demonstrated by 3-dimensional fused images of computed tomographic hepatic arteriography/unenhanced computed tomography : prognostic significance in patients who underwent transcatheter arterial chemoembolization.2010

    • Author(s)
      Tajima T, Nishie A, Asayama Y, Ishigami K, Ushijima Y, Kakihara D, Honda H.
    • Journal Title

      Journal of Computer Assisted Tomography

      Volume: 34巻 Pages: 712-719

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 3テスラMRIによる非造影MRA:臨床応用と腹部IVRにおける意義飯塚医師会学術講演会2013

    • Author(s)
      田嶋 強
    • Organizer
      第68回 筑豊画像研究会特別講演会(
    • Place of Presentation
      がみプレジデントホテル,飯塚市
    • Year and Date
      2013-01-16
    • Related Report
      2012 Final Research Report
  • [Presentation] Liver Dysfunction Induced By Amiodarone Therapy: Evaluation By Sequential CT Studies2013

    • Author(s)
      Sonoyma Y; Tajima T; Shiga T; Hagiwara N; Sakai S
    • Organizer
      ECR 2013
    • Place of Presentation
      Austria Center Vienna、Vienna、Austria
    • Related Report
      2012 Final Research Report
  • [Presentation] 4D Time-SLIP: How To Do It2013

    • Author(s)
      Tajima T, Shinohara M, Yamamoto T, Sakai1 S
    • Organizer
      ECR 2013
    • Place of Presentation
      Austria Center Vienna、Vienna、Austria
    • Related Report
      2012 Final Research Report
  • [Presentation] Liver Dysfunction Induced By Amiodarone Therapy: Evaluation By Sequential CT Studies2013

    • Author(s)
      Sonoyma, Y, Tajima T, Shiga T, Hagiwara N, Sakai1 S.
    • Organizer
      ECR 2013
    • Place of Presentation
      Austria Center Vienna、ウイーン、オーストリア
    • Related Report
      2012 Annual Research Report
  • [Presentation] 4D Time-SLIP: How To Do It2013

    • Author(s)
      Tajima T, Shinohara M, Yamamoto T, Sakai1 S.
    • Organizer
      ECR 2013
    • Place of Presentation
      Austria Center Vienna、ウイーン、オーストリア
    • Related Report
      2012 Annual Research Report
  • [Presentation] 3テスラMRIによる非造影MRA:臨床応用と腹部IVRにおける意義2013

    • Author(s)
      田嶋 強
    • Organizer
      飯塚医師会学術講演会 第68回 筑豊画像研究会特別講演会
    • Place of Presentation
      のがみプレジデントホテル,飯塚市
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 膵胆道系疾患のCT ・MRI診断:悪性腫瘍の質的診断と鑑別診断を中心に2012

    • Author(s)
      田嶋 強
    • Organizer
      第52回日本核医学会学術総会
    • Place of Presentation
      ロイトン札幌、札幌市
    • Year and Date
      2012-10-12
    • Related Report
      2012 Final Research Report
  • [Presentation] Detectability of renal arteries in living renal donors using MDCT: comparison among axial images and three-dimensional reconstruction images2012

    • Author(s)
      Kohno M, Tajima T, et al.
    • Organizer
      ECR 2012
    • Place of Presentation
      Austria Center Vienna、Vienna、Austria
    • Related Report
      2012 Final Research Report
  • [Presentation] Medium-Term Results After Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma: Estimation of Safety Margins Using Three-Dimensional Fused Images of Computed Tomographic Hepatic Arteriography/Unenhanced Computed Tomography2012

    • Author(s)
      Kimura K; Tajima T; Asayama Y; Ushijima Y; Nishie A; Honda H; Sakai S
    • Organizer
      98th scientific assembly & annual meeting,Radiological Society of North America
    • Place of Presentation
      Chicago, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] Three-dimensional Noncontrast-enhanced MR Angiography Using Time-SLIP: Why We Have to Use a New Tool as Pre-interventional Evaluation of Renal Diseases2012

    • Author(s)
      Tajima T; Shimizu S; Yamamoto T; Shinohara M; Kohno M; Sakai S
    • Organizer
      98th scientific assembly & annual meeting,Radiological Society of North America
    • Place of Presentation
      Chicago, USA.
    • Related Report
      2012 Final Research Report
  • [Presentation] 3テスラ装置を用いたMRアンギオグラフィ~腎疾患診療における初期経験2012

    • Author(s)
      田嶋 強
    • Organizer
      第71回日本医学放射線学会総会
    • Place of Presentation
      パシフィコ横浜,横浜市
    • Related Report
      2012 Final Research Report
  • [Presentation] Medium-Term Results After Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma: Estimation of Safety Margins Using Three-Dimensional Fused Images of Computed Tomographic Hepatic Arteriography/Unenhanced Computed Tomography2012

    • Author(s)
      Kimura K; Tajima T; Asayama Y; Ushijima Y; Nishie A; Honda H; and Sakai S
    • Organizer
      98th scientific assembly & annual meeting,Radiological Society of North America
    • Place of Presentation
      マコーミックプレイス、シカゴ市、アメリカ合衆国
    • Related Report
      2012 Annual Research Report
  • [Presentation] Three-dimensional Noncontrast-enhanced MR Angiography Using Time-SLIP: Why We Have to Use a New Tool as Pre-interventional Evaluation of Renal Diseases2012

    • Author(s)
      Tajima; Seiko Shimizu; Takao Yamamoto; Maiko Shinohara; Mari Kohno; and Shuji Sakai
    • Organizer
      98th scientific assembly & annual meeting,Radiological Society of North America
    • Place of Presentation
      マコーミックプレイス、シカゴ市、アメリカ合衆国
    • Related Report
      2012 Annual Research Report
  • [Presentation] 3テスラ装置を用いたMRアンギオグラフィ~腎疾患診療における初期経験~2012

    • Author(s)
      田嶋 強
    • Organizer
      第71回 日本医学放射線学会総会
    • Place of Presentation
      パシフィコ横浜,横浜市
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 膵胆道系疾患のCT・MRI診断:悪性腫瘍の質的診断と鑑別診断を中心に2012

    • Author(s)
      田嶋 強
    • Organizer
      第52回日本核医学会学術総会
    • Place of Presentation
      ロイトン札幌、札幌市
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Detectability of renal arteries in living renal donors using MDCT : comparison among axial images and three-dimensional reconstruction images2012

    • Author(s)
      Kohno M, Tajima T, et al
    • Organizer
      ECR 2012
    • Place of Presentation
      Austria Center、ウィーン市、オーストリア
    • Related Report
      2011 Annual Research Report
  • [Presentation] 腎動脈疾患に対するMR血管造影と3次元再構成画像2011

    • Author(s)
      田嶋 強.
    • Organizer
      第47回日本医学放射線学会秋季臨床大会
    • Place of Presentation
      下関海峡メッセ、生涯学習プラザ、下関市
    • Year and Date
      2011-10-21
    • Related Report
      2012 Final Research Report
  • [Presentation] 腎動脈疾患に対するMR血管造影と3次元再構成画像2011

    • Author(s)
      田嶋強
    • Organizer
      第47回日本医学放射線学会秋季臨床大会
    • Place of Presentation
      下関海峡メッセ、生涯学習プラザ、下関市(招待講演)
    • Year and Date
      2011-10-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] Three-dimensional Noncontrast-enhanced MR Angiography inTransplanted Kidneys: Techniques, Useful Conditions, and Limitations of Time-SLIP.2011

    • Author(s)
      Tajima T, et al.
    • Organizer
      97th scientific assembly & annual meeting,Radiological Society of North America
    • Place of Presentation
      Chicago, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] 生体腎移植術前ドナー腎動脈数同定能: MDCT3次元画像再構成法間の比較2011

    • Author(s)
      河野真理、 田嶋 強、他
    • Organizer
      第70回日本医学放射線学会総会
    • Place of Presentation
      横浜市
    • Related Report
      2012 Final Research Report
  • [Presentation] Three-dimensional Noncontrast-enhanced MR Angiography in Transplanted Kidneys : Techniques, Useful Conditions, and Limitations of Time-SLIP2011

    • Author(s)
      Tajima T, et al
    • Organizer
      RSNA 2011
    • Place of Presentation
      マコーミックプレイス、シカゴ市、アメリカ合衆国
    • Related Report
      2011 Annual Research Report
  • [Presentation] 生体腎移植術前ドナー腎動脈数同定能:MDCT3次元画像再構成法間の比較2011

    • Author(s)
      河野真理、田嶋強, 他
    • Organizer
      第70回日本医学放射線学会総会、
    • Place of Presentation
      横浜市(Web開催)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Safety Margins of Hepatocellular Carcinoma Demonstrated by 3D Fused Images of CT Hepatic Arteriography/Unenhanced CT: Prognostic Significance in Patients Who Underwent Transcatheter Hepatic Chemoembolization2010

    • Author(s)
      Tajima T, Nishie A, Asayama Y, Ishigami K, Ushijima Y, Kakihara D, Honda H.
    • Organizer
      96th scientific assembly & annual meeting,Radiological Society of North America
    • Place of Presentation
      Chicago, USA.
    • Related Report
      2012 Final Research Report
  • [Presentation] Safety Margins of Hepatocellular Carcinoma Demonstrated by 3D Fused Images of CT Hepatic Arteriography/Unenhanced CT : Prognostic Significance in Patients Who Underwent Transcatheter Hepatic Chemoembolization2010

    • Author(s)
      Tajima T, Nishie A, Asayama Y, Ishigami K, Ushijima Y, Kakihara D, Honda H.
    • Organizer
      北米放射線学会
    • Place of Presentation
      マコーミックプレイス、シカゴ市、アメリカ合衆国
    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.twmu.ac.jp/RAD/ign/

    • Related Report
      2012 Final Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

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