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Elucidation of the mechanism of improvement of liver function after B-RTO for gastric varices

Research Project

Project/Area Number 22591376
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionHyogo Medical University

Principal Investigator

HIROTA Shozo  兵庫医科大学, 医学部, 教授 (20181216)

Co-Investigator(Kenkyū-buntansha) KOBAYASHI Kaoru  兵庫医科大学, 医学部, 助教 (70388817)
MAEDA Hiroaki  兵庫医科大学, 医学部, 助教 (00388828)
KAKO Yasukazu  兵庫医科大学, 医学部, 助教 (40573209)
ISHIKURA Reiichi  兵庫医科大学, 医学部, 准教授 (00176174)
YAMAMOTO Satoshi  兵庫医科大学, 医学部, 助教 (50411989)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywordsインターベンショナルラジオロジー(IVR) / 肝硬変 / インターベンショナルラジオロジー / 門脈圧亢進症 / B-RTO / 肝性脳症 / 肝硬度 / 超音波エラストグラフィー / 肝線維化マーカー
Research Abstract

The mechanism of improvement of liver function after the shunt occlusion treatment was evaluated. We investigated the change of liver volume and change of hardness of the liver before and after shunt occlusion in 20 patients. Improvement of liver function was found in 10 of 20 patients. LF index of tissue elastography decreased in 16 of 20 patients. In conclusion, increase of the liver cell or congestive change of sinusioid after increase of hepatopetal liver flow.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (52 results)

All 2012 2011 2010

All Journal Article (10 results) (of which Peer Reviewed: 2 results) Presentation (38 results) (of which Invited: 1 results) Book (4 results)

  • [Journal Article] 門脈圧亢進症に対するIVRの進歩?B-RTO、PSEを中心に?、"医学のあゆみ"特集肝硬変Update?肝硬変死の根絶をめざして?2012

    • Author(s)
      廣田省三、山本聡
    • Journal Title

      医学のあゆみ

      Volume: 240巻 Pages: 747-751

    • Related Report
      2012 Final Research Report
  • [Journal Article] 合併症対策 門脈圧亢進症に対するIVRの進歩.2012

    • Author(s)
      廣田省三
    • Journal Title

      医学のあゆみ

      Volume: 240 Pages: 747-751

    • Related Report
      2012 Annual Research Report
  • [Journal Article] 1.胃静脈瘤に対するB-RTO―‐経大腿アプローチを中心に―.2012

    • Author(s)
      前田弘彰
    • Journal Title

      IVR学会誌

      Volume: 27 Pages: 83-87

    • Related Report
      2012 Annual Research Report
  • [Journal Article] B-RTOにおける長時間留置法(Overnight留置)の有用性?短時間法との比較?2011

    • Author(s)
      小林薫、廣田省三、前田弘彰、新井桂介、山本聡、加古泰一、阿知波左千子、古川佳孝、小竹正昌
    • Journal Title

      臨床放射線

      Volume: 56巻 Pages: 354-358

    • NAID

      40018750211

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] B-RTOにおける長時間留置法(Overnight留置)の有用性短時間法との比較2011

    • Author(s)
      小林薫
    • Journal Title

      臨床放射線

      Volume: 56 Pages: 354-358

    • NAID

      40018750211

    • Related Report
      2011 Annual Research Report
  • [Journal Article] Differences in trocar positioning within the vertebral body using two different positioning methods : Effect on trainee performance2011

    • Author(s)
      Hirota S
    • Journal Title

      Radiology research and practice

      Volume: 5

    • Related Report
      2011 Annual Research Report
  • [Journal Article] B-RTOにおける長時間留置法(Overnight留置)の有用性-短時間法との比較-2011

    • Author(s)
      小林薫
    • Journal Title

      臨床放射線

      Volume: 56 Pages: 354-358

    • NAID

      40018750211

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 門脈系 の interventional radiology2010

    • Author(s)
      廣田省三、前田弘彰、小林薫、阿知波左 千 子、 加古泰一 、 山本聡
    • Journal Title

      外科

      Volume: 72巻 Pages: 823-828

    • Related Report
      2012 Final Research Report
  • [Journal Article] 門脈系のinterventional radiology.2010

    • Author(s)
      廣田省三
    • Journal Title

      外科

      Volume: 72 Pages: 823-828

    • Related Report
      2010 Annual Research Report
  • [Journal Article] High Resolution Tree-dimensional T2-weighted Imaging at 3T : Finding of Cerebellopontine angle Schwannomas and Meningiomas.2010

    • Author(s)
      Ishikura, R
    • Journal Title

      Magn Reson Med Sci

      Volume: 9 Pages: 177-178

    • Related Report
      2010 Annual Research Report
  • [Presentation] The role of BRTO for portal hypertension2012

    • Author(s)
      Hirota S
    • Organizer
      CIRSE
    • Place of Presentation
      Lisbon, Portugal
    • Year and Date
      2012-09-19
    • Related Report
      2012 Final Research Report
  • [Presentation] Furukawa Y, Yamasaki M, B-RTO ? Gastric varices and port-systemic encephalopathy -2012

    • Author(s)
      Kobayashi K, Hirota S, Maeda H, Yamamoto S, Kako Y, Achiwa S
    • Organizer
      APCCVIR
    • Place of Presentation
      Kobe
    • Year and Date
      2012-06-01
    • Related Report
      2012 Final Research Report
  • [Presentation] PerfusionCTを用いたB-RTO前後での肝灌流・肝体積の評価2012

    • Author(s)
      加古泰一、前田弘彰、山崎真由子、古川佳孝、阿知波左千子、山本聡、小林薫、廣田省三、名定敏也、城本航
    • Organizer
      第71回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2012-04-15
    • Related Report
      2012 Final Research Report
  • [Presentation] The role fo BRTO for portal hypertension2012

    • Author(s)
      Shozo Hirota
    • Organizer
      Cardiovascular and Interventional Radiological Society of Europe(CIRSE2012)
    • Place of Presentation
      Lisbon, Portugal
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] B-RTO‐Gastric varices and port-systemic encephalopathy‐.Joint Meeting of the 10th Asia-Pacific Congress of Cardiovascular Interventional Radiology (APCCVIR2012)2012

    • Author(s)
      Kaoru Kobayashi
    • Organizer
      10th Asia-Pacific Congress of Cardiovascular Interventional Radiology (APCCVIR2012)
    • Place of Presentation
      Kobe, Japan
    • Related Report
      2012 Annual Research Report
  • [Presentation] Perfusion CTを用いたB-RTO前後での肝灌流・肝体積の評価2012

    • Author(s)
      Kako Yasukazu
    • Organizer
      第71回日本医学放射線学会総会
    • Place of Presentation
      横浜、神奈川
    • Related Report
      2012 Annual Research Report
  • [Presentation] Interventional radiology forportal hypertension2011

    • Author(s)
      Hirota S
    • Organizer
      APSCVIR
    • Place of Presentation
      Hanoi
    • Year and Date
      2011-09-30
    • Related Report
      2012 Final Research Report
  • [Presentation] Interventional radiology for portal hypertension2011

    • Author(s)
      Hirota S
    • Organizer
      APSCVIR
    • Place of Presentation
      ベトナム(招待講演)
    • Year and Date
      2011-09-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] MDCTを用いた脾腎シャントの形態分類?シャント型肝性脳症に対するBRTOのために?2011

    • Author(s)
      阿知波左千子、前田弘彰、山崎真由子、古川佳孝、加古泰一、若田ゆき、山本聡、小林薫、廣田省三
    • Organizer
      第18回日本門脈圧亢進症学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2011-09-16
    • Related Report
      2012 Final Research Report
  • [Presentation] MDCTを用いた脾腎シャントの形態分類~シャント型肝性脳症に対するBRTOのために~2011

    • Author(s)
      阿知波左千子
    • Organizer
      第18回日本門脈圧亢進症学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2011-09-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] 128列MDCTを用いた肝perfusionCTでのB-RTO前後の門脈血流評価について2011

    • Author(s)
      加古泰一、前田弘彰、山崎真由子、古川佳孝、阿知波左千子、山本聡、小林薫、廣田省三、名定敏也、城本航
    • Organizer
      第18回日本門脈圧亢進症学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2011-09-15
    • Related Report
      2012 Final Research Report
  • [Presentation] 128列MDCTを用いた肝perfusion CTでのB-RTO前後の門脈血流評価について2011

    • Author(s)
      加古泰一
    • Organizer
      第18回日本門脈圧亢進症学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2011-09-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] Transcatheter shunt occlusion for port-systemic encephalopathy : interventional management and clinical outcom2011

    • Author(s)
      Kobayashi K, Hirota S, MaedaH, Yamamoto S, Achiwa S, Kako Y, Furukawa Y, Yamasaki M, Igarashi Y, Katsuura T, Ishikura R
    • Organizer
      CIRSE
    • Place of Presentation
      Munich, Germany
    • Year and Date
      2011-09-10
    • Related Report
      2012 Final Research Report
  • [Presentation] 門脈圧亢進症の血行動態2011

    • Author(s)
      前田弘彰
    • Organizer
      第40回日本IVR学会総会
    • Place of Presentation
      青森
    • Year and Date
      2011-05-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] インターフェロン治療にお2るPSEの役割2011

    • Author(s)
      山本聡
    • Organizer
      第40回日本IVR学会総会
    • Place of Presentation
      青森
    • Year and Date
      2011-05-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 脾腎シャントの画像的分類の検討?シャント型肝性脳症に対するBRTOのために?2011

    • Author(s)
      阿知波左千子、前田弘彰、古川佳孝、加古泰一、若田ゆき、高田恵広、山本聡、新井桂介、小林薫、石藏礼一、廣田省三
    • Organizer
      第40回日本IVR学会総会
    • Place of Presentation
      青森
    • Year and Date
      2011-05-19
    • Related Report
      2012 Final Research Report
  • [Presentation] 脾腎シャントの画像的分類の検討~シャント型肝性脳症に対するBRTOのために~2011

    • Author(s)
      阿知波左千子
    • Organizer
      第40回日本IVR学会総会
    • Place of Presentation
      ミュンヘン
    • Year and Date
      2011-05-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] インターフェロン治療におけるPSEの役割2011

    • Author(s)
      山本聡、廣田省三、古川佳孝、阿知波左千子、加古泰一、新井桂介、小林薫、前田弘彰、西口修平、今西宏安、池田直人、飯室勇二
    • Organizer
      第40回日本IVR学会総会
    • Place of Presentation
      青森
    • Year and Date
      2011-05-11
    • Related Report
      2012 Final Research Report
  • [Presentation] 脾腎シャントによる肝性脳症に対するB-RTOの検討2011

    • Author(s)
      前田弘彰
    • Organizer
      第70回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2011-04-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] Transcatheter shunt occlusion for port-systemic encephalopathy : interventional management and clinical outcom2011

    • Author(s)
      Kobayashi K
    • Organizer
      CIRSE
    • Place of Presentation
      ミュンヘン
    • Related Report
      2011 Annual Research Report
  • [Presentation] B-RTOにおける長時間留置法(金川原法)との比較検討2010

    • Author(s)
      小林薫、前田弘彰、山本聡、新井桂介、阿知波左千子、加古泰一、古川佳孝、小竹正昌、廣田省三
    • Organizer
      第17回日本門脈圧亢進症学会総会
    • Place of Presentation
      富山
    • Year and Date
      2010-09-10
    • Related Report
      2012 Final Research Report
  • [Presentation] 128列MDCTを用いた肝PerfusionCTの初期経験2010

    • Author(s)
      加古泰一、前田弘彰、古川佳孝、阿知波左千子、若田ゆき、高田恵広、山本聡、小林薫、新井桂介、石藏礼一、廣田省三、名定敏也、城本航
    • Organizer
      第19回近畿食道・胃静脈瘤研究会
    • Place of Presentation
      大阪
    • Year and Date
      2010-07-03
    • Related Report
      2012 Final Research Report
  • [Presentation] 128列MDCTを用いた肝Perfusion CTの初期経験2010

    • Author(s)
      加古泰一
    • Organizer
      第19回近畿食道・胃静脈瘤研究会
    • Place of Presentation
      大阪
    • Year and Date
      2010-07-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] SRシャントを伴った肝性脳症に対するB-RTOの検討2010

    • Author(s)
      阿知波左千子、前田弘彰、小林薫、古川佳孝、加古泰一、若田ゆき、高田恵広、山本聡、新井桂介、石藏礼一、廣田省三
    • Organizer
      第28回日本IVR学会関西地方会
    • Place of Presentation
      大阪
    • Year and Date
      2010-06-26
    • Related Report
      2012 Final Research Report 2010 Annual Research Report
  • [Presentation] 門脈圧亢進症に対するIVR?静脈瘤、腹水、脳症をどうする?2010

    • Author(s)
      廣田省三
    • Organizer
      第37回兵庫県内視鏡治療談話会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-09
    • Related Report
      2012 Final Research Report
  • [Presentation] 門脈圧亢進症に対するIVR-静脈瘤、腹水、脳症をどうする-2010

    • Author(s)
      廣田省三
    • Organizer
      第37回兵庫県内視鏡治療談話会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] 肝性脳症に対する経皮的シャント閉鎖術の治療成績2010

    • Author(s)
      小林薫、前田弘彰、新井桂介、山本聡、加古泰一、阿知波左千子、古川佳孝、高田恵広、若田ゆき、石藏礼一、廣田省三
    • Organizer
      第39回日本IVR学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-05-21
    • Related Report
      2012 Final Research Report 2010 Annual Research Report
  • [Presentation] B-RTO for beginners2010

    • Author(s)
      Hirota,S
    • Organizer
      GrobalEmbolization Symposium and Technologies
    • Place of Presentation
      San Francisco, U.S.A.
    • Year and Date
      2010-05-06
    • Related Report
      2012 Final Research Report
  • [Presentation] B-RTO for biginners.2010

    • Author(s)
      Hirota, S
    • Organizer
      Global Embolization Symposium and Technologies.
    • Place of Presentation
      San Francisco
    • Year and Date
      2010-05-06
    • Related Report
      2010 Annual Research Report
  • [Presentation] B-RTOにおける長時間留置法(Overnight留置)の有用性:30分留置法(金川原法)との比較2010

    • Author(s)
      小林薫、前田弘彰、山本聡、新井桂介、加古泰一、小竹正昌、井上淳一、植田毅、入江美和、廣田省三
    • Organizer
      第69回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2010-04-10
    • Related Report
      2012 Final Research Report 2010 Annual Research Report
  • [Presentation] Interventional Radiology for portal hepertention2010

    • Author(s)
      Hirota,S
    • Organizer
      第69回日本医学放 射線学会総会(International Session)
    • Place of Presentation
      横浜
    • Year and Date
      2010-04-09
    • Related Report
      2012 Final Research Report
  • [Presentation] Interventional Radiology for portal hepertention. (International Session)2010

    • Author(s)
      Hirota, S
    • Organizer
      第69回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Related Report
      2010 Annual Research Report
  • [Presentation] 門脈系(ワークショップ)2010

    • Author(s)
      前田弘彰
    • Organizer
      第69回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Related Report
      2010 Annual Research Report
  • [Presentation] 胃静脈瘤に対するB-RTO不成功例の検討2010

    • Author(s)
      前田弘彰
    • Organizer
      第69回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Related Report
      2010 Annual Research Report
  • [Presentation] Clinical evaluation of transcatheter embolization for 100 pulmonary AVMs in Japan2010

    • Author(s)
      Hirota, S
    • Organizer
      Asian Pacific Congress of Cardiovascular Interventional Radiology (APCCVIR)
    • Place of Presentation
      Seoul
    • Related Report
      2010 Annual Research Report
  • [Presentation] Transcatheter coil embolization of splenic artery aneurysms. -Therapeutic strategy using original classifination-2010

    • Author(s)
      Yamamoto, S
    • Organizer
      Asian Pacific Congress of Cardiovascular Interventional Radiology (APCCVIR)
    • Place of Presentation
      Seoul
    • Related Report
      2010 Annual Research Report
  • [Presentation] B-RTOにおける長時間留置法(Overnight留置)と短時間留置法(金川原法)との比較検討2010

    • Author(s)
      小林薫
    • Organizer
      第17回日本門脈圧亢進症学会総会
    • Place of Presentation
      富山
    • Related Report
      2010 Annual Research Report
  • [Presentation] Transcatheter coil embolization of splenic artery aneurysms : therapeutic strategy using original classification.2010

    • Author(s)
      Yamamoto, S
    • Organizer
      CIRSE (Cardiovascular and Interventional Radiological Society of Europe) 2010
    • Place of Presentation
      Valencia
    • Related Report
      2010 Annual Research Report
  • [Book] 消化器の手術以外の治療と検査2012

    • Author(s)
      前田弘彰
    • Total Pages
      350
    • Publisher
      大阪 メディカル出版
    • Related Report
      2012 Annual Research Report
  • [Book] 肝硬変のマネジメント改訂版2011

    • Author(s)
      前田弘彰、小林薫、山本聡、廣田省三、2)IVR、西口修平編
    • Publisher
      医薬ジャーナル社
    • Related Report
      2012 Final Research Report
  • [Book] 肝硬変のマネジメント改訂版2011

    • Author(s)
      前田弘彰
    • Publisher
      医薬ジャーナル社
    • Related Report
      2011 Annual Research Report
  • [Book] 画像検査診断用語辞典-サイン・画像所見・症候群・検査用語2010

    • Author(s)
      廣田省三
    • Total Pages
      345
    • Publisher
      金芳堂
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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