Basic and clinical study for the protection and the treatment of gastric malignant lymphoma.
| Project/Area Number |
22591393
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Kurume University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
OOSHIMA Kouichi 久留米大学, 医学部, 教授 (50203766)
SUEFUJI Hiroaki 久留米大学, 病院, 助教 (00320200)
WATANABE Yuko 久留米大学, 医学部, 教授 (70404465)
SHIBAMOTO Yuta 名古屋市立大学, 医学(系)研究科 (20144719)
NAKAMURA Kazumasa 九州大学, 大学病院, 准教授 (20284507)
SUEFUJI Nobuko 久留米大学, 医学部, 助教 (50341342)
OGO Etuyo 久留米大学, 医学部, 教授 (20204729)
SUZUKI Gen 久留米大学, 医学部, 助教 (80279182)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 放射線腫瘍学 / 悪性リンパ腫 / 胃初発非ホジキンリンパ腫 / MALTリンパ腫 / 非MALTリンパ腫 / CD20/CXCR3 陽性Ｂリンパ球 / びまん性大細胞型Ｂ細胞リンパ腫 / 放射線治療 / 胃粘膜障害 / CD20/CXCR3陽性Bリンパ球 / びまん性大細胞型のB細胞リンパ腫 / 末梢性T細胞性リンパ腫濾胞型 / 血管免疫芽球性T細胞リンパ腫 / 胃 |
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| Research Abstract |
In order to reduce the relapse of gastric MALT lymphoma, we have targeted about the CD20/CXCR3 positive B-cells in peripheral blood. Relapse rates appeared to be different by reducing rates of the CD20/CXCR3 positive B-cells after radiation therapy to the stomach among the 18 gastric MALT lymphoma patients. But number and rates of these cells of the 10 normal volunteers were exceeded more than those of MALT lymphoma patients. There needs fundamental improvement to use the CD20/CXCR3 positive B-cells for the protection and the treatment of gastric MALT lymphoma.
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Report
(4 results)
Research Products
(59 results)
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[Journal Article] 18F-FDG uptake in primary gastric malignant lymphoma correlates with glucose transporter 1 expression and histologic malignant potential.2013
Author(s)
Watanabe Y, Suefuji H, Hirose Y, Kaida H, Suzuki G, Uozumi J, Ogo E, Miura M, Takasu K, Miyazaki K, Nakahara K, Ishibashi M, Okamura T, Ohshima K, Hayabuchi N.
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Journal Title
Int J Hematol
Volume: 97(1)
Issue: 1
Pages: 43-49
DOI
NAID
Related Report
Peer Reviewed
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[Journal Article] Cytotoxic molecule-positive classical Hodgkin's lymphoma : a clinicopathological comparison with cytotoxic molecule-positive peripheral T-cell lymphoma of not otherwise specified type2011
Author(s)
Asano N, Kinoshita T, Tamaru J, Ohshima K, Yoshino T, Niitsu N, Tsukamoto N, Hirabayashi K, Izutsu K, Taniwaki M, Morishima Y, Nakamura S
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Journal Title
Haematologica
Volume: 96
Issue: 11
Pages: 1636-1643
DOI
Related Report
Peer Reviewed
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[Presentation] 肝原発悪性リンパ腫の1例2012
Author(s)
永田翠,東南辰幸,内田政史,楠元正志角明子,隈部力,藤本公則,中島収,佐田通夫,早渕尚文
Organizer
第9回肝細胞イメージングカンファレンス
Place of Presentation
ホテルセントラーザ博多
Year and Date
2012-08-31
Related Report
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[Presentation] 久留米大学病院におけるHodgkin病の根治的放射線治療成績日本放射線腫瘍学会2012
Author(s)
末藤大明,早渕尚文,渡邉祐子,宮田裕作,服部睦行,江藤英博,鈴木弦,淡河恵津世,岡村孝,大島孝一
Organizer
第25回学術集会,東京国際フォーラム
Related Report
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[Presentation] Naofumi Hayabuchi18F-FDG uptake in primary gastric malignant lymphoma correlates with glucose transporter 1 expression and tumor aggressiveness2012
Author(s)
Yuko Watanabe, Hiroaki Suefuji, Yasumitsu Hirose, Hayato Kaida,Chikayuki Hattori,Hidehiro Eto, Gen Suzuki, Etsuyo Ogo, Masatoshi Ishibashi, Takashi Okamura, Koichi Oshima
Organizer
The XVI Meeting of the European Association for Haematopathology
Place of Presentation
Lisboa, Portugal
Related Report
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[Presentation] がんと放射線治療2011
Author(s)
早渕尚文
Organizer
第1回粒子線がん治療入門セミナー
Place of Presentation
福岡国際会議場
Year and Date
2011-07-30
Related Report
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