Intrathecal infusion of thrombolytic agent and/or vasodilator from cisterna magna for prevention and therapy of angiospasm

Research Project

Project/Area Number	22591580
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Single-year Grants
Section	一般
Research Field	Cerebral neurosurgery
Research Institution	Kanazawa University
Principal Investigator	HAMADA Jun-ichiro 金沢大学, 医学系, 教授 (40253752)
Project Period (FY)	2010 – 2012
Project Status	Completed (Fiscal Year 2012)
Budget Amount *help	¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000) Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000) Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000) Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords	大槽 / 血栓溶解 / 脳血管攣縮 / 大槽内注入
Research Abstract	Intrathecal infusion of tissure plasminogen activator between 24 and 72 hours after subarachnoid hemorrhage can prevent the angiospasm. Clearance of subarachnoid hemorrhage by thrombolytic agent is necessary for the vasodilator agent reaching the vascular wall. I t is also confirmed that vasodilator agent of SNP is most useful for the therapy of the angiospasm.

Report

(4 results)