A newly biodegradable bone cement inducing osteoanagenesis
| Project/Area Number |
22591635
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Okayama University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
OZAKI Toshifumi 岡山大学, 大学院・医歯薬学総合研究科, 教授 (40294459)
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| Co-Investigator(Renkei-kenkyūsha) |
YOSHIDA Yasuhiro 岡山大学, 大学院・医歯薬学総合研究科, 准教授 (90281162)
SHIOZAKI Yasuyuki 岡山大学, 岡山大学病院, 医員 (00596041)
MAZAKI Tetsuro 岡山大学, 岡山大学病院, 医員 (70644392)
YAMANE Kentaro 岡山大学, 岡山大学病院, 医員 (60644391)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 骨再生 / 整形外科 / 骨 / 骨セメント / 生体吸収 / リン酸化多糖 / 骨粗鬆症 / 整形外科学 |
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| Research Abstract |
The purpose of this study was to investigate the effect of new bone cement consisting of Phosphorylated Pullulan, which has the nature of bioadhesive and biodegradable. This new cement bonded significantly better to hydroxyapatite as compared with commercially available bone cements. In vivo experiments, this cement was effective for the bone reconstruction compared with calcium phosphate cement. From this fine result, we plan to continue this project so that can apply to clinical practice.
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Report
(4 results)
Research Products
(5 results)
