| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Research Abstract |
Decreased lumbar intervertebral disc (IVD) nutrition is a possible cause for IVD degeneration. Narrowing of the nutrition canal possibly leads to IVD degeneration; however, 3D nutrition canal microstructure has not been analyzed in a quantitative manner. This study aimed to characterize the normal 3D microstructure of nutrition canal of the rabbit lumbar vertebral endplate using a high-resolution micro-CT technique. The present study demonstrated a nutrition canal 3D network which consisted of vertical and horizontal canals. This study showed existence of horizontal canals interconnecting the vertical canals. Although the horizontal canal’s role is yet to be analyzed, the horizontal canals appear to contribute fluid flows within the endplate.
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