Alteration of tumor immunity and anti-cancer drug / hormone sensitivity accompanied by MMR mechanism abnormality in endometrial cancer

• Project/Area Number: 22591867
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Obstetrics and gynecology
• Research Institution: Keio University
• Principal Investigator: SUSUMU Nobuyuki 慶應義塾大学, 医学部, 講師 (90206459)
• Co-Investigator(Renkei-kenkyūsha): BANNO Kouji 慶應義塾大学, 医学部, 講師 (70265875) ; HIRASAWA Akira 慶應義塾大学, 医学部, 助教 (90296658) ; YAMAGAMI Wataru 慶應義塾大学, 医学部, 助教 (30348718)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: 婦人科腫瘍学 / 子宮内膜癌 / 腫瘍免疫 / MMR機構 / ホルモン感受性 / 黄体ホルモン療法

Research Abstract

We detected that those cases with endometrial cancer with many infiltrative regulatory T cells (Treg) were significantly poorly-differentiated or advanced-stage cancer and had poor prognosis, and that those cases with high Treg/CD8 ratio had poor prognosi

Research Products

• [Journal Article] The origin of stroma surrounding epithelial ovarian cancer cells. (2013)
  • Author(s): Akahane T, Hirasawa A, Susumu N, et al.
  • Journal Title: Int J Gynecol Pathol Volume: 32 Issue: 1 Pages: 26-30
  • DOI: 10.1097/pgp.0b013e3182518533
  • Peer Reviewed
• [Journal Article] Endocervical glandular neoplasia associated with lobular endocervical glandular hyperplasia is HPV-independent and correlates with carbonic anhydrase-IX expression: a Gynaecological Oncology Group Study. (2013)
  • Author(s): Liao SY, Rodgers WH, Susumu N, et al
  • Journal Title: Br J Cancer Volume: 108 Issue: 3 Pages: 613-620
  • DOI: 10.1038/bjc.2012.578
  • Peer Reviewed
• [Journal Article] MicroRNAs in endometrial cancer. (2013)
  • Author(s): Banno K, Yanokura M, Kisu I, Yamagami W, Susumu N, Aoki D
  • Journal Title: International journal of clinical oncology Volume: 18 Issue: 2 Pages: 186-192
  • DOI: 10.1007/s10147-013-0526-9
  • NAID: 10031176254
  • Peer Reviewed
• [Journal Article] Experience of Risk-reducingSalpingo-oophorectomy for a BRCA1 Mutation Carrier and Establishment of a System Performing a Preventive Surgery for Hereditary Breast and Ovarian Cancer Syndrome in Japan: Our Challenges for the Future (2013)
  • Author(s): Hirasawa A, Masuda K, Susumu N, et al
  • Journal Title: Jpn J Clin Oncol. Volume: 13
  • Peer Reviewed
• [Journal Article] New candidate therapeutic agents for endometrial cancer: potential for clinical practice (review). (2013)
  • Author(s): Umene K
  • Journal Title: Oncol Rep Volume: 29 Issue: 3 Pages: 855-860
  • DOI: 10.3892/or.2013.2221
  • Peer Reviewed
• [Journal Article] Progestin therapy for endometrial cancer: the potential of fourth-generation progestin (review) (2012)
  • Author(s): Banno K, Kisu I, Susumu N, et al.
  • Journal Title: Int J Oncol. Volume: 40 Pages: 1755-1762
  • DOI: 10.3892/ijo.2012.1384
  • Peer Reviewed
• [Journal Article] Epigenetics and genetics in endometrial cancer: new carcinogenic mechanisms and relationship with clinical practice. (2012)
  • Author(s): Banno K, Kisu I, Yanokura M, Masuda K, Ueki A, Kobayashi Y, Susumu N, Aoki D
  • Journal Title: Epigenomics Volume: 4 Issue: 2 Pages: 147-162
  • DOI: 10.2217/epi.12.13
  • Peer Reviewed
• [Journal Article] Endometrial Cancer and Hypermethylation: Regulation of DNA and MicroRNA by Epigenetics. (2012)
  • Author(s): Banno K, Kisu I, Yanokura M, Masuda K, Kobayashi Y, Ueki A, Tsuji K, Yamagami W, Nomura H, Susumu N, Aoki D
  • Journal Title: Biochemistry Research International Volume: 2012 Pages: 738274-738274
  • DOI: 10.1155/2012/738274
  • Peer Reviewed
• [Journal Article] Epimutation and cancer: a new carcinogenic mechanism of Lynch syndrome (Review) (2012)
  • Author(s): Banno K, Kisu I , Susumu N, et al
  • Journal Title: Int J Oncol. Volume: 41 Pages: 793-797
  • Peer Reviewed
• [Journal Article] Relationship of lower uterine segment cancer with Lynch syndrome: a novel case with an hMLH1 germline mutation (2012)
  • Author(s): Masuda K, Banno K, Susumu N, et al
  • Journal Title: Oncol Rep Volume: 28 Issue: 5 Pages: 1537-1543
  • DOI: 10.3892/or.2012.2008
  • Peer Reviewed
• [Journal Article] Lobular endocervical glandular hyperplasia and peritoneal pigmentation associated with Peutz-Jeghers syndrome due to a germline mutation of STK11 (2012)
  • Author(s): Hirasawa A, Akahane T, Susumu N, et al
  • Journal Title: Ann Oncol. Volume: 23 Issue: 11 Pages: 2990-2992
  • DOI: 10.1093/annonc/mds492
  • Peer Reviewed
• [Journal Article] Preoperative and intraoperative assessment of myometrial invasion in endometrial cancer: comparison of magnetic resonance imaging and frozen sections. (2012)
  • Author(s): Kisu I, Banno K, Susumu N, et al.
  • Journal Title: Acta Obstet Gynecol Scand Volume: 16 Issue: 5 Pages: 525-535
  • DOI: 10.1111/aogs.12048
  • Peer Reviewed
• [Journal Article] Narrow band imaging in gynecology: a new diagnostic approach with improved visual identification (Review) (2012)
  • Author(s): Kisu I, Banno K, Susumu N, et al
  • Journal Title: Int J Oncol. Volume: 40 Pages: 350-356
  • DOI: 10.3892/ijo.2011.1226
  • Peer Reviewed
• [Journal Article] Role of circulating free alu DNA in endometrial cancer (2012)
  • Author(s): Tanaka H, Tsuda H, Susumu N, et al.
  • Journal Title: Int J Gynecol Cancer Volume: 22 Issue: 1 Pages: 82-86
  • DOI: 10.1097/igc.0b013e3182328c94
  • Peer Reviewed
• [Journal Article] Expression profiles of carcinosarcoma of the uterine corpus-are these similar to carcinoma or sarcoma? (2012)
  • Author(s): Chiyoda T, Tsuda H, Susumu N, et al.
  • Journal Title: Genes Chromosomes Cancer Volume: 51 Issue: 3 Pages: 229-239
  • DOI: 10.1002/gcc.20947
  • Peer Reviewed
• [Journal Article] Biomarkers in endometrial cancer: Possible clinical applications (Review). (2012)
  • Author(s): Banno K
  • Journal Title: Oncol Lett Volume: 3 Pages: 1175-1180
  • Peer Reviewed
• [Journal Article] Epimutation and cancer: a new carcinogenic mechanism of Lynch syndrome (Review). (2012)
  • Author(s): Banno K
  • Journal Title: Int J Oncol Volume: 10.3892/ijo.2012.1528. Issue: 3 Pages: 793-797
  • DOI: 10.3892/ijo.2012.1528
  • Peer Reviewed
• [Journal Article] Retrospective study comparing irinotecan and pegylated liposomal doxorubicin in treatment of recurrent platinum-refractory/resistant epithelial ovarian cancer. (2012)
  • Author(s): Nomura H
  • Journal Title: Eur J Gynaecol Oncol Volume: 33 Pages: 86-89
  • Peer Reviewed
• [Journal Article] Association of epigenetic inactivation of the WRN gene with anticancer drug sensitivity in cervical cancer cells. (2012)
  • Author(s): Masuda K
  • Journal Title: Oncol Rep Volume: 28 Issue: 4 Pages: 1146-1152
  • DOI: 10.3892/or.2012.1912
  • Peer Reviewed
• [Journal Article] Immunofluorescence-Detected Infiltration of CD4+FOXP3+ Regulatory T Cells is Relevant to the Prognosis of Patients With Endometrial Cancer. (2011)
  • Author(s): Yamagami W, Susumu N, Tanaka H,et al
  • Journal Title: Int J Gynecol Cancer Volume: 22 Pages: 1628-1634
  • Peer Reviewed
• [Journal Article] Overexpression of cofilin 1 can predict progression-free survival in patients with epithelial ovarian cancer receiving standard therapy (2011)
  • Author(s): Nishimura S, Tsuda H, Susumu N, et al
  • Journal Title: Hum Pathol Volume: 42 Issue: 4 Pages: 516-521
  • DOI: 10.1016/j.humpath.2010.07.019
  • Peer Reviewed
• [Journal Article] Complete remission of recurrent and refractory uterine epithelioid leiomyosarcoma using weekly administration of bevacizumab and temozolomide (2011)
  • Author(s): Takano M, Kikuchi Y, Susumu N, et al
  • Journal Title: Eur J Obstet Gynecol Reprod Biol. Volume: 157 Issue: 2 Pages: 236-268
  • DOI: 10.1016/j.ejogrb.2011.02.020
  • Peer Reviewed
• [Journal Article] Expression of hypoxia-inducible 2 (HIG2) protein in uterine cancer (2011)
  • Author(s): Nishimura S, Tsuda H, Susumu N, et al
  • Journal Title: Eur J Gynaecol Oncol Volume: 32 Pages: 146-149
  • Peer Reviewed
• [Journal Article] The chemosensitivity of nodal metastases in recurrent epithelial ovarian cancer (2011)
  • Author(s): Kataoka F, Tsuda H, Susumu N, et al.
  • Journal Title: Eur J Gynaecol Oncol. Volume: 32 Pages: 160-163
  • Peer Reviewed
• [Journal Article] Preoperative differential diagnosis of minimal deviation adenocarcinoma and lobular end cervical glandular hyperplasia of the uterine cervix : a multicenter study of clinico pathology and magnetic resonance imaging findings (2011)
  • Author(s): Takatsu A, Shiozawa T, Miyamoto T, Kurosawa K, Kashima H, Yamada T, Kaku T, Mikami Y, Kiyokawa T, Tsuda H, Ishii K, Togashi K, Koyama T, Fujinaga Y, Kadoya M, Hashi A, Susumu N, Konishi I.
  • Journal Title: Int J Gynecol Cancer Volume: 21(7) Issue: 7 Pages: 1287-96
  • DOI: 10.1097/igc.0b013e31821f746c
  • Peer Reviewed
• [Journal Article] Magnifying hysteroscopy with narrow-band imaging for visualization of endometrial lesions. (2011)
  • Author(s): Kisu I, Banno K, Susumu N, et al.
  • Journal Title: Int J Gynaecol Obstet. Volume: 115 Issue: 1 Pages: 74-75
  • DOI: 10.1016/j.ijgo.2011.05.009
  • Peer Reviewed
• [Journal Article] Narrow band imaging hysteroscopy: a comparative study using randomized video images (2011)
  • Author(s): Kisu I, Banno K, Susumu N, et al
  • Journal Title: Int J Oncol. Volume: 39 Pages: 1057-1062
  • DOI: 10.3892/ijo.2011.1131
  • Peer Reviewed
• [Journal Article] Carcinoma of the Lower Uterine Segment (LUS): Clinicopathological Characteristics and Association with Lynch Syndrome (2011)
  • Author(s): Masuda K, Banno K, Susumu N, et al
  • Journal Title: Current Genomics Volume: 12 Pages: 25-29
  • Peer Reviewed
• [Journal Article] miR-152 is a tumor suppressor microRNA that is silenced by DNA hypermethylation in endometrial cancer (2011)
  • Author(s): Tsuruta T, Inazawa J, et al
  • Journal Title: Cancer Res Volume: 71 Issue: 20 Pages: 6450-6462
  • DOI: 10.1158/0008-5472.can-11-0364
  • Peer Reviewed
• [Journal Article] Relationship between DNA Mismatch Repair Deficiency and Endometrial Cancer (2011)
  • Author(s): Masuda K, Banno K, , Susumu N, et al
  • Journal Title: Mol Biol Int. Volume: 2011 Pages: 256063-256063
  • DOI: 10.4061/2011/256063
  • Peer Reviewed
• [Journal Article] Immunofluorescence-Detected Infiltration of CD4+FOXP3+ Regulatory T Cells is Relevant to the Prognosis of Patients With Endometrial Cancer (2011)
  • Author(s): Yamagami W, Susumu N, Tanaka H, et al
  • Journal Title: Int J Gynecol Cancer Volume: 21 Pages: 1628-1634
  • Peer Reviewed
• [Journal Article] Carcinoma of the Lower Uterine Segment (LUS) : Clinicopathological Characteristics and Association with Lynch Syndrome (2011)
  • Author(s): Masuda K, Banno K, Susumu N, et al
  • Journal Title: Current Genomics Volume: 12 Pages: 25-29
  • Peer Reviewed
• [Presentation] 若年子宮体癌および複雑型子宮内膜異型増殖症に対する妊孕性温存療法後のフォローアップにおける子宮内膜細胞診の有用性 (2013)
  • Author(s): 山上 亘、進 伸幸、市川義一、他
  • Organizer: 54回日本婦人科腫瘍学会
  • Place of Presentation: 東京
  • Year and Date: 2013-07-19
• [Presentation] 子宮体癌における妊孕性温存黄体ホルモン療法後の再発予後因子の検討 (2013)
  • Author(s): 進 伸幸、山上 亘、青木大輔、他
  • Organizer: 第54回日本臨床細胞学会春期大会
  • Place of Presentation: 東京
  • Year and Date: 2013-05-31
• [Presentation] 細胞診検体からの遺伝子診断を志向した微量細胞からの遺伝子解析の試み (2013)
  • Author(s): 赤羽智子、平沢 晃、進 伸幸、他
  • Organizer: 第54回日本臨床細胞学会春期大会
  • Place of Presentation: 東京
  • Year and Date: 2013-05-31
• [Presentation] The significance of hysteroscopy in endometrial cancer. Comparison between cytology and histology (2013)
  • Author(s): Takigawa A, Susumu N, Yamagami W, et al
  • Organizer: XVIIIth International Congress of Cytology
  • Place of Presentation: Paris France
  • Year and Date: 2013-05-27
• [Presentation] 高用量黄体ホルモン療法後に妊娠に至った若年性子宮体癌および複雑型子宮内膜異型増殖症43例の妊娠予後と分娩後のサーベイランス (2013)
  • Author(s): 山上 亘、進 伸幸、青木大輔、他
  • Organizer: 第65回日本産科婦人科学会
  • Place of Presentation: 札幌
  • Year and Date: 2013-05-10
• [Presentation] 若年体癌症例に対する高用量黄体ホルモン.. (MPA)療法後の生児獲得率 (2013)
  • Author(s): 滝川 彩、進 伸幸、山上 亘、他
  • Organizer: 第65回日本産科婦人科学会
  • Place of Presentation: 札幌
  • Year and Date: 2013-05-10
• [Presentation] 若年体癌症例に対する高用量黄体ホルモン(MPA)療法後の生児獲得率 (2013)
  • Author(s): 滝川 彩
  • Organizer: 第65回日本産科婦人科学会
  • Place of Presentation: 札幌
• [Presentation] The significance of hysteroscopy in endometrial cancer: Comparison between cytology and histology (2013)
  • Author(s): Takigawa A
  • Organizer: 18th International Congress of Cytology
  • Place of Presentation: Paris, France
• [Presentation] 若年子宮体癌および複雑型子宮内膜異型増殖症に対する妊孕性温存療法後のフォローアップにおける子宮内膜細胞診の有用性 (2013)
  • Author(s): 山上 亘
  • Organizer: 第54回日本婦人科腫瘍学会
  • Place of Presentation: 東京
• [Presentation] 子宮体癌におけるセンチネルリンパ節転移陽性症例の検討 (2013)
  • Author(s): 片岡史夫
  • Organizer: 第54回日本婦人科腫瘍学会
  • Place of Presentation: 東京
• [Presentation] 子宮体癌のセンチネルリンパ節探索における蛍光法の応用 (2013)
  • Author(s): 桑波田美智子
  • Organizer: 第54回日本婦人科腫瘍学会
  • Place of Presentation: 東京
• [Presentation] クリニカルカンファレンス７（腫瘍）：婦人科腫瘍に対する縮小・機能温存治療 (2013)
  • Author(s): 進 伸幸
  • Organizer: 第65回日本産科婦人科学会
  • Place of Presentation: 札幌
  • Invited
• [Presentation] 子宮体癌症例における子宮内膜細胞診偽陰性症例の後方視的検討-臨床医の立場から (2012)
  • Author(s): 山上 亘、進 伸幸、青木大輔、他
  • Organizer: 第51回日本臨床細胞学会秋季大会
  • Place of Presentation: 新潟
  • Year and Date: 2012-11-09
• [Presentation] 当院における子宮体癌 IVb 期症例の臨床病理学的検討 (2012)
  • Author(s): 滝川 彩、山上 亘、進 伸幸、他
  • Organizer: 第124回日本産科婦人科学会関東連合大会
  • Place of Presentation: 甲府
  • Year and Date: 2012-10-28
• [Presentation] Analysis of unsuccessful outcome cases among 165 young patients with endometrial cancer who received fertility-preserving hormonal therapy using medroxyprogesterone acetate (2012)
  • Author(s): Susumu N, Yamagami W, Aoki D, et al.
  • Organizer: XVth International Gynecologic Cancer Society.
  • Place of Presentation: Vancouver, Canada
  • Year and Date: 2012-10-15
• [Presentation] 子宮体癌手術における大網切除の臨床病理学的検討 (2012)
  • Author(s): 坂井健良、山上 亘、進 伸幸、他
  • Organizer: 第52回日本婦人科腫瘍学会
  • Place of Presentation: 東京
  • Year and Date: 2012-07-19
• [Presentation] 若年の子宮内膜異型増殖症症例と類内膜腺癌症例に対する妊孕性温存療法の挑戦 (2012)
  • Author(s): 進 伸幸、山上 亘、青木大輔、他
  • Organizer: 52回日本婦人科腫瘍学会
  • Place of Presentation: 東京
  • Year and Date: 2012-07-19
• [Presentation] 子宮体癌傍大動脈リンパ節単独転移例の検討 (2012)
  • Author(s): 富里祥子、山上 亘、進 伸幸、他
  • Organizer: 第123回日本産科婦人科学会関東連合大会
  • Place of Presentation: 東京
  • Year and Date: 2012-06-17
• [Presentation] メドロキシプロゲステロンアセテート(MPA)療法の非成功例の検討-子宮摘出に至った.. 37例の検討より (2012)
  • Author(s): 進 伸幸、山上 亘、青木大輔、他
  • Organizer: 第64回日本産科婦人科学会
  • Place of Presentation: 神戸
  • Year and Date: 2012-04-13
• [Presentation] Analysis of unsuccessful outcome cases among 165 young patients with endometrial cancer who received fertility-preserving hormonal therapy using medroxyprogesterone acetate (2012)
  • Author(s): Susumu N
  • Organizer: XVth International Gynecologic Cancer Society.
  • Place of Presentation: Vancouver, Canada
• [Presentation] 若年の子宮内膜異型増殖症症例と類内膜腺癌症例に対する妊孕性温存療法の挑戦 (2012)
  • Author(s): 進 伸幸
  • Organizer: 第52回日本婦人科腫瘍学会
  • Place of Presentation: 東京
  • Invited
• [Presentation] メドロキシプロゲステロン(MPA)療法の非成功例の検討 －子宮摘出に至った37例の検討より－ (2012)
  • Author(s): 進 伸幸
  • Organizer: 第64回日本産科婦人科学会
  • Place of Presentation: 神戸
• [Presentation] 子宮体癌症例における子宮内膜細胞診偽陰性症例の後方視的検討－臨床医の立場から－ (2012)
  • Author(s): 山上 亘
  • Organizer: 第51回日本臨床細胞学会秋季大会
  • Place of Presentation: 新潟
  • Invited
• [Presentation] 当院における子宮体癌IVb期症例の臨床病理学的検討 (2012)
  • Author(s): 滝川 彩
  • Organizer: 第124回日本産科婦人科学会関東連合大会
  • Place of Presentation: 甲府
• [Presentation] 早期子宮体癌症例に対するセンチネルナビゲーションシステム(SNNS）の確立に向けて (2012)
  • Author(s): 進 伸幸
  • Organizer: 第52回日本婦人科腫瘍学会
  • Place of Presentation: 東京
  • Invited
• [Presentation] 子宮体癌におけるセンチネルリンパ節ナビゲーションシステム(SNNS）の展開 (2012)
  • Author(s): 進 伸幸
  • Organizer: 第53回日本婦人科腫瘍学会
  • Place of Presentation: 岡山
  • Invited
• [Presentation] 子宮体癌のセンチネルリンパ節探索におけるRI投与方法の検討 (2012)
  • Author(s): 山上 亘
  • Organizer: 第14回センチネルノード研究会
  • Place of Presentation: 名古屋
• [Presentation] 子宮体癌のセンチネルリンパ節探索における「laterality」の検討 (2012)
  • Author(s): 片岡史夫
  • Organizer: 第14回センチネルノード研究会
  • Place of Presentation: 名古屋
• [Presentation] シンポジウム『生殖医療におけるがん・生殖医療の推進ー 若年女性のQOL 向上を目指して』 若年子宮体癌における妊孕性温存療法の治療成績と問題点 腫瘍学的側面からー (2011)
  • Author(s): 進 伸幸、山上 亘、青木大輔、他
  • Organizer: 第56回日本生殖医学会学術講演会・総会
  • Place of Presentation: 横浜
  • Year and Date: 2011-12-09
• [Presentation] シンポジウム『生殖医療におけるがん・生殖医療の推進-若年女性のQOL向上を目指して』若年子宮体癌における妊孕性温存療法の治療成績と問題点-腫瘍学的側面から- (2011)
  • Author(s): 進伸幸、山上亘、市川義一, 他
  • Organizer: 第56回日本生殖医学会学術講演会・総会
  • Place of Presentation: パシフィコ横浜(神奈川県)
  • Year and Date: 2011-12-09
• [Presentation] 若年子宮体癌例の妊孕性温存MPA療法はどこまで継続してよいのか? - 88例の長期予後解析より- (2011)
  • Author(s): 進 伸幸、山上 亘、市川義一、他
  • Organizer: 第50回日本婦人科腫瘍学会
  • Place of Presentation: 福岡
  • Year and Date: 2011-12-05
• [Presentation] 若年子宮体癌例の妊孕性温存MPA療法はどこまで継続してよいのか?-88例の長期予後解析より- (2011)
  • Author(s): 進伸幸、山上亘、市川義一, 他
  • Organizer: 第50回日本婦人科腫瘍学会
  • Place of Presentation: ホテルマリターレ創世久留米(福岡県)
  • Year and Date: 2011-12-05
• [Presentation] How long can young women with endometrial cancer be safely treated with MPA for fertility-preserving? (2011)
  • Author(s): Susumu N, Yamagami Y, Ichikawa Y, et al
  • Organizer: from a retrospective analysis of 88 cases - XVIIth Europeaan Society of Gynecologic Oncology
  • Place of Presentation: Milan, Italy
  • Year and Date: 2011-09-13
• [Presentation] How long can young women with endometrial cancer be safely treated with MPA for fertility-preserving?-from a retrospective analysis of 88 cases- (2011)
  • Author(s): Susumu N, Yamagami Y, Ichikawa Y, et al
  • Organizer: XVIIth Europeaan Society of Gynecologic Oncology
  • Place of Presentation: Milan, Italy
  • Year and Date: 2011-09-13
• [Presentation] 当院における若年子宮体癌における妊孕性温存療法の治療成績 (2011)
  • Author(s): 進 伸幸、山上 亘、青木大輔、他
  • Organizer: 第12回 ホルモンと癌研究会
  • Place of Presentation: 東京
  • Year and Date: 2011-07-15
• [Presentation] 当院における若年子宮体癌における妊孕性温存療法の治療成績 (2011)
  • Author(s): 進伸幸、山上亘、市川義一, 他
  • Organizer: 第12回ホルモンと癌研究会
  • Place of Presentation: 弘済会館(東京都)
  • Year and Date: 2011-07-15
• [Presentation] 当施設における子宮体がん特殊組織型別予後データ. (2010)
  • Author(s): 進 伸幸, 阪埜浩司, 青木大輔、他
  • Organizer: 婦人科がん肉腫研究会
  • Place of Presentation: 佐賀
  • Year and Date: 2010-12-05
• [Presentation] 当施設における子宮体がん特殊組織型別予後データ (2010)
  • Author(s): 進伸幸, 平沢晃, 田中京子, 阪埜浩司, 青木大輔
  • Organizer: 婦人科がん肉腫研究会
  • Place of Presentation: 佐賀市
  • Year and Date: 2010-12-05
• [Presentation] Fertility-preserving high-dose medroxyprogesterone acetate (MPA) therapy for 4 young patients with grade 2 endometrioid adenocarcinoma. (2010)
  • Author(s): Susumu, N., Hirasawa A., Yamagami Y.,et al.
  • Organizer: 13rd Biennial Meeting International Gynecological Cancer Society.
  • Place of Presentation: Prague (Czech Republic)
  • Year and Date: 2010-10-25
• [Presentation] Fertility-preserving high-dose medroxyprogesterone acetate (MPA) therapy for 4 young patients with grade 2 endometrioid adenocarcinoma. (2010)
  • Author(s): Susumu.N., Hirasawa A., Yamagami Y., et al.
  • Organizer: 13rd Biennial Meeting International Gynecological Cancer Society
  • Place of Presentation: Prague (Czech Republic)
  • Year and Date: 2010-10-25
• [Presentation] 子宮体癌治療のUP-DATE(化学療法を中心として) (2010)
  • Author(s): 進伸幸, 野村弘行, 青木大輔
  • Organizer: 化学療法セミナー
  • Place of Presentation: 金沢市(招請講演)
  • Year and Date: 2010-09-19
• [Presentation] 婦人科領域の癌治療の動向 (2010)
  • Author(s): 進伸幸
  • Organizer: 第19回多摩臨床セミナー
  • Place of Presentation: 立川市(招請講演)
  • Year and Date: 2010-05-22
• [Book] 婦人科がん低侵襲手術-動画で学ぶエキスパートのテクニック-- (2012)
  • Author(s): 進 伸幸, 山上 亘, 片岡史夫, 他
  • Publisher: 目地カルレビュー社
• [Book] Cancer of the uterine endometrium (2012)
  • Author(s): Susumu N
  • Total Pages: 182
  • Publisher: InTech, Croatia.
• [Book] 婦人科がん化学療法ハンドブック (2011)
  • Author(s): 進 伸幸, 平沢 晃, 阪埜浩司
  • Publisher: 青木大輔中外医学社
• [Book] Cancer of theuterine endometrium (2011)
  • Author(s): Susumu N, Nomura H, Yamagami W, et al
  • Publisher: Intech, Rijeka, Croatia
• [Book] Cancer of the uterine endometrium (2011)
  • Author(s): Susumu N, Nomura H, Yamagami W, et al
  • Total Pages: 182
  • Publisher: Intech, Rijeka, Croatia
• [Book] 婦人科がん化学療法ハンドブック (2011)
  • Author(s): 進伸幸, 平沢晃, 阪埜浩司, 青木大輔
  • Publisher: 中外医学社
• [Book] IndiaChemotherapeutic strategies for gynecological cancers (2010)
  • Author(s): Susumu N, Saito E, Nomura H, et al
  • Publisher: Transworld reseach network, Kerala