Neuroprotective effect of an antioxidant, lutein in the retina of a murine model of diabetes.
| Project/Area Number |
22591950
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Ophthalmology
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| Research Institution | Keio University |
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Principal Investigator |
SASAKI Mariko 慶應義塾大学, 医学部, 特任助教 (60276342)
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| Co-Investigator(Kenkyū-buntansha) |
OZAWA Yoko 慶應義塾大学, 医学部, 講師 (90265885)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 網膜神経保護 / 抗酸化剤 / ルテイン / 糖尿病 / 網膜神経変性 / 酸化ストレス / 神経保護 / 網膜 |
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| Research Abstract |
Diabetic retinopathy is a progressive neurodegenerative disease, but the underlying mechanism is still obscure. Here, we focused on oxidative stress in the retina, and analysed its influence on retinal neurodegeneration, using an antioxidant, lutein. Lute
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Report
(4 results)
Research Products
(13 results)
