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Analysis of newly formed neural circuit after cross-link operation for facial nerve palsy -with decellularized nerve graft-

Research Project

Project/Area Number 22591993
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Plastic surgery
Research InstitutionKobe University

Principal Investigator

HASHIKAWA Kazunobu  神戸大学, 医学部附属病院, 特命講師 (90403237)

Co-Investigator(Kenkyū-buntansha) SAKAKIBARA Shunsuke  神戸大学, 医学研究科, 特命助教 (50444592)
田原 真也  神戸大学, 医学部附属病院, 教授 (60207206)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywordsマイクロサージェリー学 / 神経再生 / 神経グラフト / 顔面神経 / クロスリンク / 顔面神経麻痺 / マイクロサージャリー / 人工神経
Research Abstract

Cross-link operation is the one of the clinical operation for facial nerve palsy. We planned to administrate the acellular nerve graft for rat cross-link model and compare the three method for decellularization, hyper osmotic method, detergent method, and freeze and thaw method. In our result, hyper osmotic method isthe one of the option for cross-link nerve graft for rat model.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (22 results)

All 2013 2012 2011 2010

All Journal Article (11 results) (of which Peer Reviewed: 11 results) Presentation (11 results)

  • [Journal Article] Classification and Terminology of Reanimation Techniques for the Paralyzed Face:"Jump Graft"and "Cross-link"2012

    • Author(s)
      Kazunobu Hashikawa
    • Journal Title

      Facial N Res Jpn

      Volume: 32 Pages: 38-40

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Immediate Facial Nerve Reconstruction with End-to-side Neurorrhaphy following Tumor Resection:Ten Consecutive Cases of End-to-side Loop Graft2012

    • Author(s)
      Kazunobu Hashikawa,Shunsuke Sakakibara
    • Journal Title

      Facial N Res Jpn

      Volume: 32 Pages: 26-28

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of reinnervation for preservation of denervated muscle volume with motor and sensory nerve: an experimental study2012

    • Author(s)
      Omori M, Sakakibara S, Hashikawa K, Terashi H, Tahara S, Sugiyama D.
    • Journal Title

      J Plast Reconstr Aesthet Surg

      Volume: 65 Pages: 943-949

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Immediate Facial Nerve Reconstruction with End―to―side Neurorrhaphy following Tumor Resection:Ten Consecutive Cases of End―to―side Loop Graft2012

    • Author(s)
      Kazunobu Hashikawa
    • Journal Title

      Facial N Res Jpn

      Volume: 32 Pages: 26-28

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of reinnervation for preservation of denervated muscle volume with motor and sensory nerve : An experimental study2012

    • Author(s)
      Makoto Omori, et al
    • Journal Title

      J Plast Reconstr Aesthet Sure

      Volume: (In press)(掲載確定)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 顔面神経麻痺に対する顔面-舌下神経クロスリンク手術と術後リハビリテーション2011

    • Author(s)
      橋川和信、榊原俊介、田原真也
    • Journal Title

      日本マイクロサージャリー学会会誌

      Volume: 24巻 3号 Pages: 267-274

    • NAID

      130004843216

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Brow Lift via an Infrabrow Approach for Facial Palsy2011

    • Author(s)
      Kasunobu Hashikawa, Shunsuke Sakakibara
    • Journal Title

      Facial N Res Jpn

      Volume: 31 Pages: 136-138

    • NAID

      10027667990

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Brow Lift via an Infrabrow Approach for Facial Palsy2011

    • Author(s)
      Kazunobu Hashikawa, et al
    • Journal Title

      Facial Nerve Research

      Volume: 31 Pages: 136-138

    • NAID

      10027667990

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 顔面神経麻痺後遺症に対する顔面-舌下神経クロスリンク手術と術後リハビリテーション2011

    • Author(s)
      橋川和信
    • Journal Title

      日本マイクロ会誌

      Volume: 24 Pages: 267-74

    • Related Report
      2011 Annual Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Therapeutic Tactics for Facial Palsy Around the Eye2010

    • Author(s)
      Kazunobu Hashikawa
    • Journal Title

      Facial N Res Jpn

      Volume: 30 Pages: 7-9

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 顔面神経麻痺の目もとに対する治療タクティクス2010

    • Author(s)
      橋川和信
    • Journal Title

      Facial Nerve Research.

      Volume: 30 Pages: 7-9

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] シンポジウムI Bell 麻痺・Hunt 症候群の新しい治療戦略2013

    • Author(s)
      橋川和信
    • Organizer
      第36回日本顔面神経研究会
    • Place of Presentation
      那覇
    • Related Report
      2012 Annual Research Report
  • [Presentation] 顔面神経麻痺に対する形成外科手術2011

    • Author(s)
      橋川 和信
    • Organizer
      平成 23 年度日本形成外科学会秋季学術講習会
    • Place of Presentation
      東京
    • Year and Date
      2011-10-05
    • Related Report
      2012 Final Research Report
  • [Presentation] 顔面神経麻痺に対する形成外科手術2011

    • Author(s)
      橋川和信
    • Organizer
      平成23年度日本形成外科学会秋季学術講習会
    • Place of Presentation
      ハイアットリージェンシー東京(東東都)(招待講演)
    • Year and Date
      2011-10-05
    • Related Report
      2011 Annual Research Report
  • [Presentation] 顔面神経麻痺に対する眉毛下アプローチ眉毛挙上術2011

    • Author(s)
      橋川 和信
    • Organizer
      第29回日本頭蓋顎顔面外科学会学術集会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] 陳旧性顔面神経麻痺に対する顔面神経-舌下神経クロスリンク手術:長期観察例の検討2011

    • Author(s)
      橋川 和信
    • Organizer
      第38回日本マイクロサージャリー学会学術集会
    • Place of Presentation
      新潟
    • Related Report
      2012 Final Research Report
  • [Presentation] 顔面神経麻痺に対する眉毛下切開・眉毛挙上術2011

    • Author(s)
      橋川 和信
    • Organizer
      第34回日本顔面神経研究会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] 顔面神経麻痺に対する眉毛下切開・眉毛挙上術2011

    • Author(s)
      橋川和信
    • Organizer
      第34回日本顔面神経研究会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 陳旧性顔面神経麻痺に対する顔面神経-舌下神経クロスリンク手術:長期観察例の検討2011

    • Author(s)
      橋川和信
    • Organizer
      第38回日本マイクロサージャリー学会学術集会
    • Place of Presentation
      朱鷺メッセ(新潟県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 顔面神経麻痺に対する眉毛下アプローチ眉毛挙上術2011

    • Author(s)
      橋川和信
    • Organizer
      第29回日本頭蓋顎顔面外科学会学術集会
    • Place of Presentation
      グランドプリンスホテル高輪(東京都)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 顔面神経麻痺の目もとに対する治療タクティクス2010

    • Author(s)
      橋川 和信
    • Organizer
      第33回日本顔面神経研究会
    • Place of Presentation
      福岡
    • Related Report
      2012 Final Research Report
  • [Presentation] 顔面神経麻痺の目もとに対する治療タクティクス2010

    • Author(s)
      橋川和信
    • Organizer
      第33回日本顔面神経研究会
    • Place of Presentation
      福岡大学8号館 831号教室(福岡県)(招待講演)
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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