Study of the treatment of oral malignant tumor using nanotechnology

• Project/Area Number: 22592104
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Pathobiological dentistry/Dental radiology
• Research Institution: Kanagawa Dental College
• Principal Investigator: MIYOSHI Yoshiko 神奈川歯科大学, 歯学部, 講師 (70288075)
• Co-Investigator(Kenkyū-buntansha): KUBOTA Nobuhisa 神奈川歯科大学, 歯学部, 講師 (20234495) ; SUZUKI Kenzi 神奈川歯科大学, 歯学部, 講師 (80350536)
• Co-Investigator(Renkei-kenkyūsha): KUBOTA Yoshinobu 横浜市立大学, 医学部, 教授 (10106312)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
• Keywords: 実験腫瘍学 / 光触媒酸化チタン / ナノテクノロジー / 口腔悪性腫瘍 / 癌治療 / 光照射

Research Abstract

Photo catalyst titanium oxide (TiO2) is a reaction chemically. TiO2 have the strong oxidation power on the surface by light irradiation. Application to new cancer treatment is expected. Already, The human bladder bladder cancer cell have been identified the cell killing effect by the interaction of light and TiO2. Study of clinical application of these is recommended. TiO2 and the light irradiation are promising for superficial cancer treatment. We have to clarify the mechanism and conditions and the possibility of treatmentwith light irradiation effect and TiO2 using nano technology in malignant oral area tumors.

Research Products

• [Presentation] IADR/AADR/CADR General Session & Exhibition 91st General Session & Exhibition of the International Association for DentalResearch (IADR) (2013)
  • Author(s): Y. MIYOSHI , N. KUBOTA1, K. SUZUKI,and K. TSUKINOKI
  • Organizer: the 42nd Annual Meeting of the American Association for Dental Research (AADR) and the 37th Annual Meeting of theCanadian Association for Dental Research (CADR)
  • Place of Presentation: The Washington State Convention Center, 800Convention Place, Seattle, Washington,98101, USA.
• [Presentation] Study to treat locally oral tumors using titanium oxide (2013)
  • Author(s): OY. MIYOSHI^1, N. KUBOTA^1, K. SUZUKI^2, K. TSUKINOKI^3
  • Organizer: IADR/AADR/CADR General Session & Exhibition 91st General Session & Exhibition of the International Association for DentalResearch (IADR), which will be held in conjunction with the 42nd Annual Meeting of the American Association for Dental Research (AADR) and the 37th Annual Meeting of the Canadian Associati on for Dental Research (CADR).
  • Place of Presentation: The Washington State Convention Center, 800Convention Place, Seattle, Washington, 98101, USA.