Effect of functional monomers and photo-initiators in dental adhesive: molecular level analysis

• Project/Area Number: 22592120
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Conservative dentistry
• Research Institution: Okayama University
• Principal Investigator: OGAWA Tatsuyuki 岡山大学, 医歯(薬)学総合研究科, 助手 (10346421)
• Co-Investigator(Kenkyū-buntansha): YOSHIDA Yasuhiro 岡山大学, 大学院医歯薬学総合研究科, 准教授 (90281162)
• Project Period (FY): 2010-04-01 – 2014-03-31
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
• Keywords: 保存修復学 / 機能性モノマー / 光重合開始剤 / アパタイト / エナメル質 / 象牙質 / 歯学 / 接着 / 界面 / 10-MDP

Research Abstract

Dental self-etch adhesives contain functional monomers and photoinitiator system for polymerization. Few studies have investigated the effect of the functional monomer and polymerization system on the polymerization efficiency of the adhesive. We tested the effect of different functional monomers and photo-initiator systems on the degree of conversion of different adhesive formulations. Our study showed the polymerization conversion of an adhesive can be affected by the functional monomer, but this depends on the photo-initiator system used. This results might be useful for developing new adhesives.

Research Products

• [Journal Article] Novel fluoro-carbon functional monomer for dental bonding (2014)
  • Author(s): Yoshihara K, Yoshida Y, Hayakawa S, Nagaoka N, Kamenoue S, Okihara T, Ogawa T, Nakamura M, Osaka A, Van Meerbeek B
  • Journal Title: J Dent Res Volume: 93(2) Issue: 2 Pages: 189-94
  • DOI: 10.1177/0022034513514447
  • Peer Reviewed
• [Journal Article] Bone tissue response to implant surfaces functionalized with phosphate-containing polymers (2014)
  • Author(s): Cardoso MV, Chaudhari A, Yoshida Y, Van Meerbeek B, Naert I, Duyck J
  • Journal Title: Clin Oral Implants Res Volume: 25(1) Issue: 1 Pages: 91-100
  • DOI: 10.1111/clr.12053
  • Peer Reviewed
• [Journal Article] Adhesive interfacial interaction affected by different carbon-chain monomers (2013)
  • Author(s): Yoshihara K, Yoshida Y, Nagaoka N, Hayakawa S, Okihara T, De Munck J, Maruo Y, Nishigawa G, Minagi S, Osaka A, Van Meerbeek B
  • Journal Title: Dent Mater Volume: 29(8) Issue: 8 Pages: 888-97
  • DOI: 10.1016/j.dental.2013.05.006
  • Peer Reviewed
• [Journal Article] HEMA inhibits interfacial nano-layering of the functional monomer MDP (2012)
  • Author(s): Yoshida Y, Yoshihara K, Hayakawa S, Nagaoka N, Okihara T, Matsumoto T, Minagi S, Osaka A, Van Landuyt K, Van Meerbeek B
  • Journal Title: J Dent Res Volume: 91(11) Issue: 11 Pages: 1060-5
  • DOI: 10.1177/0022034512460396
  • Peer Reviewed
• [Journal Article] Self-assembled Nano-layering at the Adhesive Interface (2012)
  • Author(s): Y.Yoshida
  • Journal Title: Journal of Dental Research Volume: 91 Issue: 4 Pages: 376-381
  • DOI: 10.1177/0022034512437375
  • Peer Reviewed
• [Journal Article] X-ray diffraction analysis of three-dimensional self-reinforcing monomer and its chemical interaction with tooth and hydroxyapatite (2012)
  • Author(s): Yoshida Y, Yoshihara K, Nagaoka N, Hanabusa M, Matsumoto T, Momoi Y
  • Journal Title: Dent Mater J Volume: 31(4) Pages: 697-702
  • NAID: 10030502018
  • Peer Reviewed
• [Journal Article] Effects of functional monomers and photo-initiators on the degree of conversion of a dental adhesive (2012)
  • Author(s): Oguri M, Yoshida Y, Yoshihara K, Miyauchi T, Nakamura Y, Shimoda S, Hanabusa M, Momoi Y, Van Meerbeek B
  • Journal Title: Acta Biomater Volume: 8(5) Issue: 5 Pages: 1928-34
  • DOI: 10.1016/j.actbio.2012.01.013
  • Peer Reviewed
• [Journal Article] Nano-layering of phosphoric-acid ester monomer at enamel and dentin (2011)
  • Author(s): Yoshihara, K., Yoshida, Y., et al
  • Journal Title: Acta Biomaterialia Volume: 7 Issue: 8 Pages: 3187-3195
  • DOI: 10.1016/j.actbio.2011.04.026
  • Peer Reviewed
• [Journal Article] Nano-layering of phosphoric-acid ester monomer at enamel and dentin (2011)
  • Author(s): Yoshihara, K., Yoshida, Y., et al
  • Journal Title: Journal of Dental Research Volume: 90 Issue: 5 Pages: 602-606
  • DOI: 10.1177/0022034510397197
  • Peer Reviewed
• [Journal Article] State of the art of self-etch adhesives (2011)
  • Author(s): Van Meerbeek B, Yoshihara K, Yoshida Y, Mine A, De Munck J, Van Landuyt KL
  • Journal Title: Dent Mater Volume: 27(1) Issue: 1 Pages: 17-28
  • DOI: 10.1016/j.dental.2010.10.023
• [Journal Article] Enamel-smear compromises bonding by mild self-etch adhesives (2010)
  • Author(s): M ine A, De Munck J, Vivan Cardoso M, Van Landuyt KL, Poitevin A, Kuboki T, Yoshida Y, Suzuki K, Van Meerbeek B
  • Journal Title: J Dent Res Volume: 89(12) Issue: 12 Pages: 1505-9
  • DOI: 10.1177/0022034510384871
  • Peer Reviewed
• [Journal Article] Nano-controlled molecular interaction at adhesive interfaces for hard tissue reconstruction (2010)
  • Author(s): Yoshihara K, Yoshida Y, Nagaoka N, Fukegawa D, Hayakawa S, Mine A, Nakamura M, Minagi S, Osaka A, Suzuki K, Van Meerbeek B
  • Journal Title: Acta Biomater Volume: 6(9) Issue: 9 Pages: 3573-82
  • DOI: 10.1016/j.actbio.2010.03.024
  • Peer Reviewed
• [Journal Article] TEM characterization of a silorane composite bonded to enamel/dentin (2010)
  • Author(s): Mine A, De Munck J, Van Ende A, Cardoso MV, Kuboki T, Yoshida Y, Van Meerbeek B
  • Journal Title: Dent Mater Volume: 26(6) Issue: 6 Pages: 524-32
  • DOI: 10.1016/j.dental.2010.01.010
  • Peer Reviewed
• [Presentation] Competition of osteoblasts and fibroblasts at early stages of osseointegration (2013)
  • Author(s): Yoshihara K, Yoshida Y, Harimoto K, Nagaoka N, Tagawa Y, Van Meerbeek B
  • Organizer: CED-IADR
  • Place of Presentation: Florence, Italy
• [Presentation] Potential Interference of Functional Monomers with Polymerization Efficiency of Adhesives (2013)
  • Author(s): Hanabusa M, Yoshida Y, Yoshihara K, Okihara T, Momoi Y, Van Meerbeek B
  • Organizer: IADR/AADR/CADR General Session and Exhibition
  • Place of Presentation: Seattle, USA
• [Presentation] Modern Adhesive Approaches for Durable Bonding to Tooth Tissue (2013)
  • Author(s): Van Meerbeek B, Yoshihara K, Van Landuyt K, De Munck J, Yoshida Y
  • Organizer: IADR/AADR/CADR General Session and Exhibition
  • Place of Presentation: Seattle, USA
• [Presentation] Nano-layering of two Phosphoric-acid monomer containg self-etch adhesives bonded to dentin (2012)
  • Author(s): Yoshihara K, Nagaoka N, Van Landuyt K, Yoshida Y, Van Meerbeek B
  • Organizer: AODES Meeting
  • Place of Presentation: Leuven - Belgium
  • Year and Date: 2012-05-11
• [Presentation] Effect of HEMA on bonding efficiency of 10-MDP to hydroxyapatite (2011)
  • Author(s): Yoshihara K, Yoshida Y, Hayakawa S, Nagaoka N, Van Landuyt KL, Osaka A, Suzuki K, Minagi S, Van Meerbeek B
  • Organizer: CED-IADR
  • Place of Presentation: Budapest, Hungary
• [Presentation] The Basics of Adhesion to Enamel and Dentin According to the AD Concept (2011)
  • Author(s): Van Meerbeek B, Yoshihara K, De Munck J, Van Landuyt KL, Yoshida Y
  • Organizer: CED-IADR
  • Place of Presentation: Budapest, Hungary
• [Presentation] Chemical Interaction of Novel Functional Monomers with Hydroxyapatite and Dentin (2010)
  • Author(s): Yoshihara K, Van Languyt KL, Yoshida Y, Nagaoka N, Hayakawa S, Osaka A, Suzuki K, Van Meerbeek, Minagi S
  • Organizer: 88th General Session & Exhibition of the IADR
  • Place of Presentation: Barcelona, Spain
• [Presentation] 接着技術の応用による医用材料の高機能化 (2010)
  • Author(s): 吉田靖弘
  • Organizer: 日本歯科保存学2010年度会秋季学術大会(第133回)・第12回日韓歯科保存学会学術大会 シンポジウムII
  • Place of Presentation: 岐阜