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Reevaluation of α-tricalcium phosphate foam which is not suitable for bone substitute material

Research Project

Project/Area Number 22592184
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Dental engineering/Regenerative dentistry
Research InstitutionYamaguchi University

Principal Investigator

UDOH Koh-ichi  山口大学, 大学院・理工学研究科, 准教授 (60145266)

Co-Investigator(Kenkyū-buntansha) UEYAMA Yoshiya  山口大学, 大学院医学系研究科, 教授 (00168668)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywordsα型リン酸三カルシウム / 骨補填材 / 足場材 / フォーム / 骨補填剤 / リン酸カルシウム / リン酸三カルシウム / 3次元連通気孔
Research Abstract

Fully interconnected -TCP foam was able to be fabricated using the polyurethane foam method, whereby polyurethane foam coated with -TCP slurry was sintered at 1,450 1,550°C and that no quenching was performed. The -TCP foam had extremely high porosity ranging between 90 and 95% and exhibited reasonable compressive strength ranging between 50 and 250 kPa. Based on these initial findings, it is highly recommended that in vivo evaluation be carried out to explore the possibility and suitability of -TCP foam as a bone substitute and/or scaffolding material for tissue engineering.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (6 results)

All 2012 2011 2010

All Journal Article (6 results) (of which Peer Reviewed: 6 results)

  • [Journal Article] The enhancement of tumor radioresponse by combined treatment with cepharanthine is accompanied by the inhibition of DNA damage repair and the induction of apoptosis in oral squamous cell carcinoma2012

    • Author(s)
      Harada T, Harada K, Ueyama Y
    • Journal Title

      Int J Oncol

      Volume: 41 Pages: 565-572

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 口腔扁平上皮癌における分子標的薬Bortezomib とTS-1 の併用効果についての基礎的研究2011

    • Author(s)
      原田豊子, 原田耕志, 上山吉哉
    • Journal Title

      頭頸部

      Volume: 37巻 Pages: 536-541

    • NAID

      10030815616

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of apatite-coated titanium prepared by blast coating and flame spray methods-Evaluation using simulated body fluid and initial histological study2011

    • Author(s)
      Mano T, Ishikawa K, Harada K, Uchida H, Ueyama Y
    • Journal Title

      Dental Materials Journal

      Volume: 30 Pages: 431-437

    • NAID

      10029338467

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of sintering temperature on physical and compositional properties of a-tricalcium phosphate foam2010

    • Author(s)
      Udoh K,Munar M.L, Maruta M, Matsuya S, Ishikawa K
    • Journal Title

      Dent Mater J

      Volume: 29 Pages: 154-159

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of sintering temperature on physical and compositional properties of .ALPHA.-tricalcium phosphate foam2010

    • Author(s)
      K.udoh, ほか4名
    • Journal Title

      Dental Materials Journal

      Volume: 29 Issue: 2 Pages: 154-159

    • DOI

      10.4012/dmj.2009-079

    • NAID

      10026192817

    • ISSN
      0287-4547, 1881-1361
    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of sintering temperature on physical and compositional properties of a-tricalcium phosphate foam2010

    • Author(s)
      K.UDOH, M.L.MUNAR, M.MARUTA, S.MATSUYA, K.ISHIKAWA
    • Journal Title

      Dental Materials Journal

      Volume: 26 Pages: 154-159

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

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