Establishment of ligament-like tissue and tight epithelial seal on chemically modified titanium surfaces
| Project/Area Number |
22592191
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Health Sciences University of Hokkaido |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
ENDO Kazuhiko 北海道医療大学, 歯学部, 教授 (70168821)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | ジルコニア / チタン / ヒト歯根膜細胞 / ヒト歯肉上皮細胞 / ヒト歯根膜由来細胞 |
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| Research Abstract |
We have performed studies aiming at improving the defense ability for bacterial infection of peri-implant soft tissues by establishing the periodontal ligament-like tissues around the titanium implant. It was indicated in the study that (i) FGF-2 was effective in culturing periodontal ligament stem cells, which are considered to be inevitable for establishingperiodontal ligament-like tissues around dental implants, and that (ii) titanium surfaceimmobilized with type I collagen was suitable for developing periodontal ligament-like tissues on the surface.
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Report
(4 results)
Research Products
(14 results)
