Basic research on the influence of obesity, menopause, lymphatics, and honey on the clean healing of full-thickness cutaneous wounds
| Project/Area Number |
22592363
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Fundamental nursing
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SUGAMA Junko 金沢大学, 保健学系, 教授 (00203307)
KONYA Chizuko 金沢医科大学, 看護学部, 教授 (20303282)
OKUWA Mayumi 金沢大学, 保健学系, 教授 (30303291)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 基礎看護学 / 看護技術 / 看護ケア / 皮膚創傷治癒 / 皮膚熱傷創 / 蜂蜜 / エストロゲン / プラズマ / あかしあ蜂蜜 / 加齢 / 皮膚全層欠損創 / ハイドロコロイドドレッシンング材 / アルゴンガス / 雄マウス / 日本産蜂蜜 / ハイドロコロイド被覆材 / 雌マウス / 皮膚創傷治癒過程 / マウス / インドネシア蜂蜜 / 肥満マウス / 高脂肪食 / 閉経 / 週令 |
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| Research Abstract |
We investigated factors that affect the healing of full-thickness cutaneous wounds in mice. Estrogen was effective for wound healing in ovariectomized mouse, but not in male mouse. There is room for further investigation on whether it is effective only in females. The effect of isoflavone on wound healing was not clear. It was also unclear whether obesity caused a delay of wound healing because the obese mice dramatically lost weight after wounding. It is thus necessary to re-examine models of obesity. Inhibition of lymphangiogenesis seemed to delay the healing. Since the effect of honey on wounds or burn wounds depended on the type of honey, it is necessary to evaluate several kinds of honey.
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Report
(4 results)
Research Products
(60 results)
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[Journal Article] The effect of isoflavone-daidzein oral medication on cutaneous wound healing in female ovariectomized mice2012
Author(s)
Kanae Mukai, Mari Nagasawa, Eri Nakamura, Natsuki Nishida, Ayaka Hori, Yukari Yagi, Aya Yamagishi, Ai Watanabe, Tamae Urai, Kana Takada, Yuriko Hara, Yukari Nakajima, Mayumi Okuwa, Miho Shogenzi, Toshio Nakatani
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Journal Title
Structure and Function(形態・機能)
Volume: 10
Pages: 94-100
NAID
Related Report
Peer Reviewed
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[Presentation] 日本産蜂蜜の皮膚創傷治癒への効果2012
Author(s)
中島由加里, 中野友貴, 木下彩香, 鶴原友輔, 西野華純, 林夏海, 平床幸穂, 不破野苑, 横川吉香, 宮原愛, 望月剛, 村角直子, 大桑麻由美, 安川緑, 中谷壽男
Organizer
第117回日本解剖学会総会・全国学術集会
Place of Presentation
山梨大学(山梨県)
Year and Date
2012-03-26
Related Report
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[Presentation] 雄マウスへのエストロゲン経皮投与が創傷治癒に及ぼす影響2011
Author(s)
中島由加里, 江野有香, 平田真理子, 向井加奈恵, 小堀佐和子, 杉浦綾乃, 竹内麻衣子, 谷口美穂, 谷崎愛, 林明日華, 疋島啓子, 松尾直樹, 和田菜摘, 大桑麻由美, 中谷壽男
Organizer
第41回日本創傷治癒学会
Place of Presentation
ウィンチ愛知(愛知県)
Year and Date
2011-12-06
Related Report
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