| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Research Abstract |
We investigated factors that affect the healing of full-thickness cutaneous wounds in mice. Estrogen was effective for wound healing in ovariectomized mouse, but not in male mouse. There is room for further investigation on whether it is effective only in females. The effect of isoflavone on wound healing was not clear. It was also unclear whether obesity caused a delay of wound healing because the obese mice dramatically lost weight after wounding. It is thus necessary to re-examine models of obesity. Inhibition of lymphangiogenesis seemed to delay the healing. Since the effect of honey on wounds or burn wounds depended on the type of honey, it is necessary to evaluate several kinds of honey.
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